Home > Inhibitors & Agonists > Nuclear Receptor/Transcription Factor > Glucocorticoid receptor (GR)
Cat. No. Product name CAS No.
DC11517 Benzodrocortisone

A synthetic glucocorticoid corticosteroid..

28956-89-0
DC11541 AZD-9567

AZD-9567 (AZD9567) is a potent, selective, non-steroidal and orally available selective glucocorticoid receptor modulator (SGRM) for treatment of rheumatoid arthritis..

1893415-00-3
DC11542 AZD-9567 monohydrate

AZD-9567 (AZD9567) is a potent, selective, non-steroidal and orally available selective glucocorticoid receptor modulator (SGRM) for treatment of rheumatoid arthritis..

1893415-64-9
DC8694 Cortodoxone

Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone).

152-58-9
DCAPI1355 Loteprednol etabonate

Loteprednol etabonate

82034-46-6
DC11203 ORIC-101

ORIC-101 (ORIC101) is a highly potent, selective steroidal glucocorticoid receptor (GR) antagonist (IC50=5.6 nM) with reduced androgen receptor (AR) agonistic activity.

2222344-98-9
DC28573 BI 653048

BI 653048 is a selective and orally active nonsteroidal glucocorticoid (GC) agonist with an IC50 value of 55 nM. BI 653048 inhibits CP1A2, CYP2D6, CYP2C9, CYP2C19 and CYP3A4 isoforms’ activity and reduces affinity for the hERG ion channel (IC50>30 μM). BI 653048 is extracted from patent WO2005028501A1 (Compound 103), is also a HCV NS3 protease inhibitor that can reduce viral loads infected with the hepatitis C virus.

1198784-72-3
DC40002 Budesonide impurity C

Budesonide impurity C is an impurity of Budesonide. Budesonide, an inhaled glucocortical steroid, is an orally active glucocorticoid receptor agonist.

1040085-99-1
DC40890 21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione

21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione is an intermediate of delta 9,11 steroids synthesis, for example, Vamorolone?(HY-109017). The delta 9,11 steroids are modifications of glucocorticoids and has anti-inflammatory properties. The delta 9,11 steroids are agents for protection against cell damage (lipid peroxidation) and inhibition of neovascularization.

37413-91-5
DC44913 Prednisone acetate

Prednisone acetate (Betapar, Cortan, Deltasone, Fernisone, Meticorten, Prednisone 21-acetate) is a glucocorticoid steroid that can be used as a glucocorticoid receptor agonist with anti-inflammatory and immunomodulating properties.,glucocorticoid receptor [1]()

125-10-0
DC46951 Dazucorilant

Dazucorilant (CORT113176) is a selective and high affinity non-steroidal glucocorticoid receptor (GR) modulator with a Ki value <1 nM in vitro. Dazucorilant can be used for the research of neurological disorders.

1496508-34-9
DC47081 Zavacorilant

Zavacorilant is capable of modulating glucocorticoid receptor (GR).

1781245-13-3
DC47207 Dagrocorat hydrochloride

Dagrocorat (PF-00251802) hydrochloride is an orally active and selective high-affinity partial agonist of the glucocorticoid receptor. Dagrocorat hydrochloride is also a time-dependent reversible inhibitor of CYP3A (IC50=1.3 μM in human liver microsomes) and CYP2D6 (Ki=0.57 μM in human liver microsomes). Dagrocorat hydrochloride can be used for the research of rheumatoid arthritis.

1044535-61-6
DC47633 Glucocorticoids receptor agonist 2

Glucocorticoids receptor agonist 2 is a potent anti-inflammatory, arylpyrazole-based glucocorticoid receptor agonist that does not impair insulin secretion.

614761-20-5
DC47634 Glucocorticoids receptor agonist 1

Glucocorticoids receptor agonist 1 is a potent anti-inflammatory, arylpyrazole-based glucocorticoid receptor agonist that does not impair insulin secretion.

694526-54-0
DC48405 BAY 1003803

BAY 1003803 is a glucocorticoid receptor agonist for the topical treatment of psoriasis or severe atopic dermatitis.

1152781-51-5
DC50226 Hydrocortisone-d3

Hydrocortisone-d3 (Cortisol-d3) is the deuterium labeled Hydrocortisone. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex.

115699-92-8
DC50227 Cortodoxone-d5

Cortodoxone-d5 (11-Deoxycortisol-d5) is the deuterium labeled Cortodoxone.

1258063-56-7
DC50228 Cortodoxone-d2

Cortodoxone-d2 (11-Deoxycortisol-d2) is the deuterium labeled Cortodoxone. Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone).

1271728-08-5
DC50229 Glucocorticoids receptor agonist 3

Glucocorticoids receptor agonist 3 is a potent agonist of glucocorticoids receptor. Glucocorticoids receptor agonist 3 is useful to research diseases, such as obesity, diabetes, and inflammation (extracted from patent WO2000066522A1, compound 345).

305821-96-9
DC70396 Exicorilant

Exicorilant (CORT125281, CORT-125281) is a potent, selective glucocorticoid receptor (GR) antagonist, exhibits no cross-reactivity for the PR and AR receptors.

1781244-77-6
DC70563 LEO 134310

LEO 134310 (LP 0155) is a non-steroidal, potent and selective glucocorticoid receptor (GR) agonist (EC50=2 nM, hPBMC).LEO 134310 is rapidly deactivated in the blood resulting in low systemic exposure and a higher therapeutic index in the TPA-induced skin inflammation mouse model compared with betamethasone valerate (BMV) and clobetasol propionate (CP).LEO 134310 displays high selectivity for GR in a panel of nuclear receptors, including the mineralocorticoid receptor (MR).LEO 134310 exhibits full efficacy on GR transactivation and transrepression.LEO 134310 may be suitable for long-term topical treatment of inflammatory skin diseases.

2089130-74-3
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