Cat. No. | Product name | CAS No. |
DC11823 |
BMS-929075
A highly potent, selective, orally bioavailable HCV NS5B polymerase inhibitor with IC50 of 9, 4, and 18 nM for GT1a, GT1b, and GT1b-C316N mutant in HCV replicon assay, respectively. |
1217338-97-0 |
DC11825 |
MK-8876
A novel, broadly acting non-nucleoside inhibitor of HCV NS5B polymerase with IC50 of 3 nM and 2 nM for GT1b and GT2a, respectively. |
1426960-33-9 |
DC11731 |
Ruzasvir
A potent, pan-genotype HCV NS5A inhibitor with replicon EC90 of 0.003, 0.016, 0.067, 0.036, 0.007, and 0.007 nM for GT1a, GT1a L31V, GT1a Y93H, GT2b, GT3a, and Gt4a, respectively.. |
1613081-64-3 |
DC7541 |
Balapiravir
Balapiravir (R1626, Ro 4588161) is the prodrug of a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R1479, RG1479). |
690270-29-2 |
DC5077 |
Boceprevir(EBP 520; SCH 503034 )
Featured
Boceprevir(EBP 520; SCH 503034 ) is useful for Anti HCV. |
394730-60-0 |
DC11081 |
Coblopasvir
Coblopasvir (KW136, KW-136) is a novel HCV NS5A inhibitor under development for treatment of HCV infection.. |
1312608-46-0 |
DC11214 |
Cyclophilin inhibitor C31
Cyclophilin inhibitor C31 (SMCypI C31) is a small-molecule cyclophilin (CypA) inhibitor (SMCypI) with PPIase inhibition IC50 of 0.1 uM, displays anti-HCV activity (HCV Gt1b replicon EC50=0.4 uM) and disrupts the CypA-NS5A interaction. |
|
DC7394 |
Daclatasvir dihydrochloride (BMS-790052)
Featured
Daclatasvir (BMS-790052) is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture. |
1009119-65-6 |
DC8238 |
Danoprevir
Featured
Danoprevir is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM, inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A. |
850876-88-9 |
DC10818 |
ABT-493(Glecaprevir)
Featured
Glecaprevir is a novel HCV NS3/4A protease inhibitor, with IC50 values ranging from 3.5 to 11.3 nM. |
1365970-03-1 |
DC11494 |
INX-08189
INX-08189 is a phosphoramidate prodrug of O-6-methyl-2-C-methyl guanosine, potent inhibitor of HCV NS5B polymerase with IC50 of 10 nM in replicon assay. |
1234490-83-5 |
DC8178 |
Beclabuvir(BMS-791325)
non-nucleoside inhibitor of the NS5B |
958002-33-0 |
DC8183 |
Paritaprevir(Veruprevir ABT-450)
Featured
NS3/4A protease inhibitor |
1216941-48-8 |
DC10728 |
Pibrentasvir(ABT-530)
Featured
Pibrentasvir is a novel and pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with EC50s ranging from 1.4 to 5.0 pM against HCV replicons containing NS5A from genotypes 1 to 6. |
1353900-92-1 |
DC4121 |
PSI6130
Featured
PSI-6130(R 1656) is a Hepatitis C Virus Nucleoside Inhibitor. PSI-6130(R 1656) is useful for Antiviral agents. |
817204-33-4 |
DC9462 |
R-7128(Mericitabine)
Featured
R-7128(Mericitabine) is a selective nucleoside analog inhibitor of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, with activity across all HCV genotypes. |
940908-79-2 |
DC8190 |
Ravidasvir hydrochloride (PPI-668)
Featured
Ravidasvir(PPI-668) is a NS5A Inhibitor. |
1303533-81-4 |
DC8612 |
Simeprevir(TMC-435)
Simeprevir (TMC 435350) is a potent inhibitor of HCV NS3/4A protease (Ki = 0.36 nM) and viral replication (replicon EC50 = 7.8 nM). |
923604-59-5 |
DC9463 |
Tegobuvir (GS-9190; GS 333126)
Featured
Tegobuvir (GS-9190; GS 333126) is a non-nucleoside nonstructural protein (NS)5B polymerase inhibitor. |
1000787-75-6 |
DC1008 |
Telaprevir (VX-950)
Featured
Telaprevir (VX-950) is an HCV NS3-4A serine protease inhibitor with IC50 of 0.35 μM. |
402957-28-2 |
DC10104 |
VX222(Lomibuvir)
Featured
VCH-222(Lomibuvir) is a novel, potent and selective inhibitor of HCV polymerase with IC50 of 0.94-1.2 μM, 15.3-fold less effective for mutant M423T, and 108-fold less effective for mutant I482L. |
1026785-59-0 |
DC9751 |
Velpatasvir(GS5816)
Featured
Velpatasvir(GS-5816) is a potent and selective Hepatitis C virus NS5A inhibitor. |
1377049-84-7 |