DCS-091 |
Cephalomannine |
>98%,Standard References |
|
DCC-002 |
Vinblastine |
>98%,Standard References |
|
DCAPI1525 |
5-Azacytidine
Featured
|
5-Azacytidine is a potent growth inhibitor and a cytotoxic agent. 5-Azacytidine acts as a demethylating agent by inhibiting DNA methyltransferase (Dnmt), forming covalent adducts with cellular DNMT1 depleting enzyme activity. 5-Azacytidine also improves t |
|
DC8944 |
5-Fluorouracil |
5-Fluorouracil is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. |
|
DC11932 |
GPX-150 |
A doxorubicin analog that demonstrates anti-cancer activity without cardiotoxicity, does not inhibit topoisomerase IIβ activity at 100 uM. |
|
DC8923 |
AS-1413(Amonafide) |
Amonafide(AS1413) produces protein-associated DNA-strand breaks through a topoisomerase II-mediated reaction, but does not produce topoisomerase I-mediated DNA cleavage. |
|
DC9832 |
Betulinic acid
Featured
|
Betulinic acid, a pentacyclic triterpene, selectively induces apoptosis in tumor cells, also is a inhibitor of HIV-1 with EC50 of 1.4 μ M. |
|
DC4186 |
Cabazitaxel |
Cabazitaxel (Jevtana, XRP6258) is a semi-synthetic derivative of a natural taxoid. |
|
DC9095 |
Carboplatin
Featured
|
Carboplatin is a chemotherapy drug by binding to DNA and interfering with the cell's repair mechanism. |
|
DC2099 |
cis-Diaminedichloroplatinum
Featured
|
Cisplatin is an inorganic platinum agent (cis-diamminedichloroplatinum) with antineoplastic activity. |
|
DC9013 |
Cyclophosphamide
Featured
|
Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities. |
|
DC7069 |
Daunorubicin HCL
Featured
|
Daunorubicin HCl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM. |
|
DCAPI1475 |
Dexrazoxane Hydrochloride |
Dexrazoxane Hydrochloride |
|
DC11192 |
Elacytarabine |
Elacytarabine (CP-4055, CP4055) is a fatty acid derivative of cytarabine with potential antineoplastic activity. |
|
DC5882 |
Fosbretabulin disodium
Featured
|
Fosbretabulin disodium(CA 4DP; CA 4P) is a microtubule destabilizing drug, a type of vascular-targeting agent, a drug designed to damage the vasculature (blood vessels) of cancer tumors causing central necrosis. |
|
DC2108 |
Gemcitabine free base |
Gemcitabine(Gemzar) belongs to the group of medicines called antimetabolites. |
|
DC8946 |
Gimeracil |
Gimeracil(Gimestat) is an inhibitor of dihydropyrimidine dehydrogenase (DPYD), which degrades pyrimidine including 5-fluorouracil in the blood; inhibits homologous recombination. |
|
DC8111 |
Idarubicin Hydrochloride
Featured
|
Idarubicin Hcl is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. |
|
DC9014 |
Ifosfamide |
Ifosfamide is a nitrogen mustard alkylating agent used in the treatment of cancer. |
|
DC10406 |
Imisopasem manganese |
Imisopasem manganese (M40403) is a stable non-peptidyl mimetic of manganese superoxide MnSOD. |
|
DC9050 |
Melphalan
Featured
|
Melphalan(Sarcolysin; L-PAM) is a chemotherapy drug belonging to the class of nitrogen mustard alkylating agents; attaches the alkyl group to the guanine base of DNA. |
|
DC4182 |
Temozolomide
Featured
|
Methazolastone (Temozolomide, Temodar, Temodal) is a DNA damage inducer. |
|
DC9298 |
thiotepa
Featured
|
N,N’N’-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group. |
|
DC7023 |
Ombrabulin
Featured
|
Ombrabulin (AVE8062) hydrochloride is a synthetic derivative of CA-4-P, which inhibits growth in a large number of drug-resistant animal tumors and carcinogen-induced tumors. |
|
DC5885 |
Oxaliplatin
Featured
|
Oxaliplatin is a second generation potent platinum-based anti-neoplastic agent that is believed to form inter- and intrastrand DNA adducts which activate signaling pathways culminating in apoptosis. The development of Oxaliplatin was inspired from the eff |
|
DC8149 |
Pemetrexed disodium
Featured
|
Pemetrexed disodium is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively. |
|
DC9359 |
Pralatrexate
Featured
|
Pralatrexate(Folotyn) is an antifolate, and structurally a folate analog. |
|
DC8940 |
Raltitrexed
Featured
|
Raltitrexed(ZD1694), an inhibitor of thymidylate synthase, is an antimetabolite drug used in cancer chemotherapy. |
|
DC7762 |
RX-3117
Featured
|
RX-3117 is an orally available and potent DNA synthesis inhibitor with potential antineoplastic activity. |
|
DC10444 |
Sapacitabine (CYC682)
Featured
|
Sapacitabine is an orally bioavailable pyrimidine analogue prodrug with potential antineoplastic activity. |
|