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Chemotherapeutic Agents

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Cat. No. Product Name Field of Application Chemical Structure
DCS-091 Cephalomannine >98%,Standard References
DCC-002 Vinblastine >98%,Standard References
DCAPI1525 5-Azacytidine Featured 5-Azacytidine is a potent growth inhibitor and a cytotoxic agent. 5-Azacytidine acts as a demethylating agent by inhibiting DNA methyltransferase (Dnmt), forming covalent adducts with cellular DNMT1 depleting enzyme activity. 5-Azacytidine also improves t
DC8944 5-Fluorouracil 5-Fluorouracil is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools.
DC11932 GPX-150 A doxorubicin analog that demonstrates anti-cancer activity without cardiotoxicity, does not inhibit topoisomerase IIβ activity at 100 uM.
DC8923 AS-1413(Amonafide) Amonafide(AS1413) produces protein-associated DNA-strand breaks through a topoisomerase II-mediated reaction, but does not produce topoisomerase I-mediated DNA cleavage.
DC9832 Betulinic acid Featured Betulinic acid, a pentacyclic triterpene, selectively induces apoptosis in tumor cells, also is a inhibitor of HIV-1 with EC50 of 1.4 μ M.
DC4186 Cabazitaxel Cabazitaxel (Jevtana, XRP6258) is a semi-synthetic derivative of a natural taxoid.
DC9095 Carboplatin Featured Carboplatin is a chemotherapy drug by binding to DNA and interfering with the cell's repair mechanism.
DC2099 cis-Diaminedichloroplatinum Featured Cisplatin is an inorganic platinum agent (cis-diamminedichloroplatinum) with antineoplastic activity.
DC9013 Cyclophosphamide Featured Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.
DC7069 Daunorubicin HCL Featured Daunorubicin HCl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM.
DCAPI1475 Dexrazoxane Hydrochloride Dexrazoxane Hydrochloride
DC11192 Elacytarabine Elacytarabine (CP-4055, CP4055) is a fatty acid derivative of cytarabine with potential antineoplastic activity.
DC5882 Fosbretabulin disodium Featured Fosbretabulin disodium(CA 4DP; CA 4P) is a microtubule destabilizing drug, a type of vascular-targeting agent, a drug designed to damage the vasculature (blood vessels) of cancer tumors causing central necrosis.
DC2108 Gemcitabine free base Gemcitabine(Gemzar) belongs to the group of medicines called antimetabolites.
DC8946 Gimeracil Gimeracil(Gimestat) is an inhibitor of dihydropyrimidine dehydrogenase (DPYD), which degrades pyrimidine including 5-fluorouracil in the blood; inhibits homologous recombination.
DC8111 Idarubicin Hydrochloride Featured Idarubicin Hcl is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor.
DC9014 Ifosfamide Ifosfamide is a nitrogen mustard alkylating agent used in the treatment of cancer.
DC10406 Imisopasem manganese Imisopasem manganese (M40403) is a stable non-peptidyl mimetic of manganese superoxide MnSOD.
DC9050 Melphalan Featured Melphalan(Sarcolysin; L-PAM) is a chemotherapy drug belonging to the class of nitrogen mustard alkylating agents; attaches the alkyl group to the guanine base of DNA.
DC4182 Temozolomide Featured Methazolastone (Temozolomide, Temodar, Temodal) is a DNA damage inducer.
DC9298 thiotepa Featured N,N’N’-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group.
DC7023 Ombrabulin Featured Ombrabulin (AVE8062) hydrochloride is a synthetic derivative of CA-4-P, which inhibits growth in a large number of drug-resistant animal tumors and carcinogen-induced tumors.
DC5885 Oxaliplatin Featured Oxaliplatin is a second generation potent platinum-based anti-neoplastic agent that is believed to form inter- and intrastrand DNA adducts which activate signaling pathways culminating in apoptosis. The development of Oxaliplatin was inspired from the eff
DC8149 Pemetrexed disodium Featured Pemetrexed disodium is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively.
DC9359 Pralatrexate Featured Pralatrexate(Folotyn) is an antifolate, and structurally a folate analog.
DC8940 Raltitrexed Featured Raltitrexed(ZD1694), an inhibitor of thymidylate synthase, is an antimetabolite drug used in cancer chemotherapy.
DC7762 RX-3117 Featured RX-3117 is an orally available and potent DNA synthesis inhibitor with potential antineoplastic activity.
DC10444 Sapacitabine (CYC682) Featured Sapacitabine is an orally bioavailable pyrimidine analogue prodrug with potential antineoplastic activity.
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