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Home > Research Areas > Inflammation/Autoimmune Disease > Dermatitis

Dermatitis

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Cat. No. Product Name Field of Application Chemical Structure
DC10141 E6005 Featured
E6005 potently and selectively inhibited human PDE4 activity with an IC50 of 2.8 nM and suppressed the production of various cytokines from human lymphocytes and monocytes with IC50 values ranging from 0.49 to 3.1 nM.
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DC7815 Crisaborole(AN-2728) Featured
AN-2728 is a topically administered, boron-containing, anti-inflammatory compound that inhibits PDE4 activity and thereby suppresses the release of TNFalpha, IL-12, IL-23 and other cytokines.
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DC10399 PAC-14028
PAC-14028 is a potent and selective transient receptor potential vanilloid type I (TRPV1) antagonist.
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