DC9450 |
(R)-Baclofen |
(R)-Baclofen(STX209) is a selective GABAB receptor agonist. |
|
DCE-016 |
Chenodeoxycholic acid |
>98%,Standard References |
|
DC11919 |
Arimoclomol
Featured
|
A nontoxic heat shock protein (HSP) coinducer and potentiator of the heat shock response. |
|
DC11920 |
Arimoclomol maleate
Featured
|
A nontoxic, orally active heat shock protein (HSP) coinducer and potentiator of the heat shock response. |
|
DC11515 |
Azeloprazole |
A novel potent proton pump inhibitor that irreversibly inhibits H+,K+-ATPase activity with IC50 of 0.28 uM. |
|
DC11546 |
Azeloprazole sodium |
A novel potent, orally active proton pump inhibitor that irreversibly inhibits H+,K+-ATPase activity with IC50 of 0.28 uM. |
|
DC11519 |
Ceclazepide |
A potent, selective cholecystokinin receptor CCK2 antagonist for treatment of gastroesophageal reflux disease (GERD).. |
|
DC11688 |
Avacopan
Featured
|
Avacopan is a potent, selective, orally availale C5aR (CD88) inhibitor with IC50 of 0.1 nM. |
|
DC11525 |
Mocravimod |
A synthetic immunosuppressant that functions as a S1P1 receptor agonist. |
|
DC11512 |
Acrizanib
Featured
|
Acrizanib(LHA510) is a potent and selective angiogenesis inhibitor and VEGFR‑2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascular Age-Related Macular Degeneration. |
|
DC8606 |
Alvimopan monohydrate |
Alvimopan(LY 246736; ADL 8-2698) is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery. |
|
DC8605 |
Alvimopan dihydrate |
Alvimopan(LY 246736; ADL 8-2698) is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery. |
|
DC11076 |
Ampreloxetine |
Ampreloxetine (TD-9855) is a potent monoamine reuptake inhibitor with pIC50 of 8.0, 8.6 and 6.8 for human NET, SERT, and DAT, respectively. |
|
DC9034 |
Atomoxetine HCl |
Atomoxetine Hcl(LY 139603; Tomoxetine Hcl) is a potent and selective noradrenalin re-uptake inhibitor (Ki values are 5, 77 and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively). |
|
DC8971 |
Baclofen |
Baclofen is a gamma-amino-butyric acid (GABA) derivative used as a skeletal muscle relaxant. |
|
DC8895 |
benzbromaron
Featured
|
Benzbromarone is a highly effective and well tolerated non-competitive inhibitor of xanthine oxidase, used as an uricosuric agent, used in the treatment of gout. |
|
DC11354 |
Carteolol (hydrochloride) |
Carteolol is an antagonist of β-adrenergic receptors (Kd = 13 nM). |
|
DC4160 |
CB-03-01
Featured
|
CB-03-01 is a steroidal ester, androgen antagonist derived from 11-deoxycortisone, which tightly mimics the profile of an ideal anti-androgen for topical use. |
|
DC9183 |
Clomiphene citrate |
Clomifene Citrate is a selective estrogen receptor modulator. |
|
DCAPI1091 |
Conivaptan hydrochloride
Featured
|
Conivaptan(YM 087) is a non-peptide inhibitor of antidiuretic hormone (vasopressin receptor antagonist) with Ki values of 0.48 and 3.04 nM for rat liver V1A receptor and rat kidney V2 receptor respectively. |
|
DC4132 |
CP-547632
Featured
|
CP-547632 is as a potent inhibitor of the VEGFR-2 and basic fibroblast growth factor (FGF) kinases (IC50 11 and 9 nM, respectively). |
|
DC11082 |
Danicopan (ACH-4471)
Featured
|
Danicopan (ACH-4471, ACH-0144471) is a highly potent, orally active Factor D inhibitor with Kd of 0.54 nM, inhibits the proteolytic activity of purified Factor D against substrate Factor B in complex with C3b, blocking production of Bb fragment IC50 of 15 nM. |
|
DC9116 |
Dantrolene sodium |
Dantrolene sodium is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm. Dantrolene sodium is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction. |
|
DCAPI1107 |
Deferasirox (Exjade)
Featured
|
Deferasirox (Exjade) |
|
DC9604 |
Desogestrel
Featured
|
Desogestrel(Org-2969) is a third-generation 19-nortestosterone derivative progestogen; is contained in many oral contraceptive preparations, both combined (COCs) to ethinyl-estradiol (EE) or alone in a progestin-only pill (POP). |
|
DC8485 |
E-64d(Aloxistatin)
Featured
|
E-64D is an inhibitor of cathepsins B and L; also thought to inhibit calpain,showed a potent activity for COVID-19(SARS-COV-2)with EC50: MERS-COV(1.275),SARS-COV(0.760) |
|
DC10939 |
Edasalonexent |
Edasalonexent (CAT-1004) is a bifunctional, orally administered small molecule that covalently links 2 compounds known to inhibit NF‐κB, salicylic acid and docosahexaenoic acid (DHA). |
|
DC9771 |
ACU4429,ACU 4429,ACU-4429
Featured
|
Emixustat hydrochloride strongly inhibits 11-cis-retinol production with IC50 values of 232 ± 3 nM. |
|
DC10314 |
Emixustat |
Emixustat, a novel visual cycle modulator, is an inhibitor of the visual cycle isomerase with an IC50 value of 4.4 nM in vitro. |
|
DC11433 |
Vatiquinone |
EPI-743 (Vatiquinone,EPI-589) is an orally bioavailable para-benzoquinone for treatment of inherited mitochondrial diseases, an analogue of the antioxidant ubidecarenone. |
|