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Pyruvate Dehydrogenase Kinase (PDK)

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Cat. No. Product Name Field of Application Chemical Structure
DC29230 Sodium dichloroacetate Sodium dichloroacetate is a metabolic regulator in cancer cells' mitochondria with anticancer activity. Sodium dichloroacetate inhibits PDHK, resulting in decreased lactic acid in the tumor microenvironment. Sodium dichloroacetate increases reactive oxygen species (ROS) generation and promotes cancer cell apoptosis. Sodium dichloroacetate also works as NKCC inhibitor.
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