| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC11822 | YD-277 | A novel small molecule KLF5 inhibitor derived from ML264, demonstrates >10-fold enhanced efficacy in multiple cancer cell lines with IC50 of 1.5-10 uM. |
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| DC9682 | ML-264 Featured | ML264 is a novel small molecule inhibitor of Krüppel-like factor 5 (KLF5). |
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| DC39108 | SR18662 Featured | SR18662 is an optimized compund based on ML264 that inhibits Krüppel-like factor 5 (KLF5) with IC50 of 4.4 nM. SR18662 reduces the viability of multiple colorectal cancer cell lines. SR18662 induces apoptosis. |
|
| DC48418 | SR15006 Featured | SR15006 is a inhibitor of Krüppel-like factor 5 (KLF5) with an IC50 of 41.6 nM in DLD-1/pGL4.18hKLF5p cells). |
|
| DC73843 | NC114 | NC114 is a small molecule targeting cancer-associated KLF5 transcription factor, decreases the KLF protein but not mRNA levels of KLF in vitro. |
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