| DCS-019 |
(-)-Huperzine A |
>98%,Standard References |
|
| DC11538 |
AD-35 |
A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates. |
|
| DC11539 |
AD-35 hydrochloride |
A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates. |
|
| DC11537 |
AD-35 phosphate |
A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates. |
|
| DC8798 |
Acotiamide
Featured
|
Acotiamide acts as an acetylcholinesterase inhibitor |
|
| DC11361 |
Dipivefrin (hydrochloride) |
Dipivefrin is a prodrug of epinephrine that is hydrolyzed by cholinesterase and other esterases in the cornea to epinephrine. |
|
| DC3155 |
Donepezil hydrochloride
Featured
|
Donepezil is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM , respectively. |
|
| DC9102 |
Donepezil |
Donepezil(E 2020) is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM, respectively. |
|
| DC7861 |
(-)-Narwedine
Featured
|
Galantamine(Narwedin) is a competitive and reversible cholinesterase(AChE) inhibitor. |
|
| DC9090 |
Galanthamine hydrobromide |
Galanthamine hydrobromide is a long-acting, centrally active acetylcholinesterase(AChE) inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. |
|
| DC9329 |
(±)-Huperzine A |
Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD). |
|
| DC12118 |
Luteolin-3-O-beta-D-glucuronide |
Luteolin-3-O-beta-D-glucuronide is a luteolin glucosiduronic acid consisting of luteolin having a beta-D-glucosiduronic acid residue attached at the 3'-position. |
|
| DCAPI1460 |
Naratriptan hydrochloride |
Naratriptan Hydrochloride is a triptan drug which is used for the treatment of migraine headaches. |
|
| DC9046 |
Neostigmine bromide |
Neostigmine Bromide is a cholinesterase inhibitor used in the treatment of myasthenia gravis. |
|
| DCAPI1543 |
Neostigmine Methylsulfate |
Neostigmine Methyl Sulfate is a reversible acetylcholinesterase inhibitor. This compound blocks the breakdown of acetylcholine in the synaptic space, leading to prolonged signaling and thus increased muscle contractions. |
|
| DCAPI1435 |
Rivastigmine tartrate |
Rivastigmine hydrogen tartrate is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer’s type and Parkinson's disease. |
|
| DC9125 |
Sumatriptan succinate |
Sumatriptan succinate is a serotonin1 (5-HT1) receptor agonist, which is effective in the acute treatment of migraine headache. |
|
| DC9976 |
(+)-Narwedine
Featured
|
(+)-Narwedine. Galantamine(Narwedin) is a competitive and reversible cholinesterase(AChE) inhibitor. |
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|
| DC28158 |
Phenserine |
Phenserine ((-)-Eseroline phenylcarbamate) is a derivative of Physostigmine and is a potent, noncompetitive, long-acting and selective AChE inhibitor. Phenserine reduces β-amyloid precursor protein (APP) and β-amyloid peptide (Aβ) formation. Phenserine improves cognitive performance and attenuates the progression of Alzheimer's disease. |
|
| DC29172 |
Obidoxime dichloride
Featured
|
Obidoxime dichloride is a non-full spectrum oxime agent and can be used as an antidote for organophosphate nerve agent poisoning. Obidoxime dichloride reactivates sarin-inhibited acetylcholinesterase (AChE) and reduces acute toxicity of sarin-evaluated. |
|
| DC40081 |
Ebeiedinone |
Ebeiedinone, a steroidal alkaloid from Fritillaria species, inhibits the bioactivity of human whole blood cholinesterase (ChE) at the concentration of 0.1 mM, with the inhibitory effects of 69.0%. |
|
| DC40256 |
Pirimicarb |
Pirimicarb is a fast-acting selective carbamate insecticide on a wide range of crops including cereals, sugar beet, potatoes, fruits and vegetables. Pirimicarb is an AChE inhibitor and an acaricide. |
|
| DC40309 |
Huperzine C |
Huperzine C is an alkaloid isolated from Huperzia serrate. Huperzine C is an acetylcholinesterase (AChE) inhibotor, with an IC50 of 0.6 μM. Huperzine C can be used for the research of Alzheimer’s Disease. |
|
| DC40528 |
Dihydro Donepezil |
Dihydro Donepezil (Dihydro E2020) is a metabolite of Donepezil. Donepezil is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bAChE and hAChE, respectively. |
|
| DC40730 |
Rivastigmine carbamate impurity |
Rivastigmine carbamate impurity (3-Nitrophenyl ethyl(methyl)carbamate) is an impurity of Rivastigmine. Rivastigmine is an orally active and potent cholinesterase (ChE) inhibitor and inhibits butyrylcholinesterase (BChE) and acetylcholinesteras (AChE) with IC50s of 0.037 μM, 4.15 μM, respectively. |
|
| DC40996 |
Chlorpyrifos-oxon |
Chlorpyrifos-oxon, an active metabolite of Chlorpyrifos, is a potent phosphorylating agent that potently inhibits AChE. Chlorpyrifos-oxon can induce cross-linking between subunits of tubulin and disrupt microtubule function. |
|
| DC41201 |
Acephate |
Acephate is an anticholinesterase insecticide that produces cholinotoxicity. Acephate displays weak inhibition of rat AChE but potently inhibits cockroach AChE. |
|
| DC41298 |
Jatrorrhizine hydroxide |
Jatrorrhizine?hydroxide is an alkaloid isolated from?Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities. Jatrorrhizine hydroxide is a potent and orally active inhibitor of?AChE?(IC50=872 nM) over >115-fold selectivity for BuChE. Jatrorrhizine hydroxide reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters. |
|
| DC41303 |
Vomifoliol |
Vomifoliol, a compound related to abscisie acid (ABA), has a modified 2,4-pentadiene side chain and has activity equal to that displayed by ABA. Vomifoliol exhibits antiacetylcholinesterase activity and displays moderate antileishmanial activity. |
|
| DC41322 |
Picfeltarraegenin X |
Picfeltarraenin X, a triterpenoid isolated from Picria fel-terrae Lour, is an AChE inhibitor. |
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