| DC11650 |
Ro5-4864
Featured
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A potent, selective ligand for the mitochondrial translocator protein 18kDa (TSPO/PBR). |
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| DC11640 |
PK-11195
Featured
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PK 11195 is a ligand of translocator protein. It targets Leishmania chemotherapy (IC50s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis, L. major and L. braziliensis, respectively). |
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| DC9259 |
DAA1106
Featured
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DAA1106 is a potent and selective ligand for peripheral benzodiazepine receptors, in mitochondrial fractions of the rat brain. |
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| DC70409 |
FGIN-1-27
Featured
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FGIN-1-27 is an anxiolytic compound that acts as a selective agonist at the peripheral benzodiazepine receptor (TSPO).FGIN-1-27 inhibited Th17 cell differentiation, significantly downregulated the expression of RORγt target genes, notably Il17a, Il17f, Il23r, Ltb4r1,Ccr6.FGIN-1-27 protected mice against EAE, induced amino acid starvation response (AAR), FGIN-1-27 produced anti-anxiety and anti-panic effects in non-mammalian models. |
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