| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC11439 | Nemorexant Featured | ACT-541468 is a dual orexin receptor antagonist. |
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| DC7692 | Almorexant HCl (Act-078573) Featured | Almorexant(ACT078573) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM for OX1 and OX2, respectively. |
|
| DC11028 | EMD-281014 hydrochloride | EMD-281014 hydrochloride is a potent, highly selective 5-HT2A antagonist with Ki of 0.87 nM, displays little to no affinity for 5-HT2C receptors (Ki=557 nM), human D2 receptors and IKr channels. |
|
| DC11027 | EMD-281014 | EMD-281014 is a potent, highly selective 5-HT2A antagonist with Ki of 0.87 nM, displays little to no affinity for 5-HT2C receptors (Ki=557 nM), human D2 receptors and IKr channels. |
|
| DC11090 | GR3027 Featured | GR3027 (Golexanolone) is a GABA-A receptor modulating steroid antagonist that selectively antagonizes the enhanced activation of GABAA receptors by neurosteroids such as allopregnanolone and THDOC. |
|
| DC4137 | Indiplon Featured | Indiplon is a novel sedative-hypnotic recently approved for the treatment of insomnia. |
|
| DC8173 | Lemborexant(E2006) Featured | Lemborexant (E-2006) is a dual antagonist of the orexin OX1 and OX2 receptors which is under development for treatment of insomnia. |
|
| DC8642 | Lorediplon Featured | Lorediplon is a new GABAA modulator Drug for treatment of insomnia. |
|
| DC9966 | MK-1064 Featured | MK-1064 is a selective orexin 2 receptor antagonist (2-SORA) for the research of insomnia. |
|
| DC7646 | MK3697 | MK-3697 is a third insomnia drug, currently being developed by Merck. MK-3697 is a potent and selective Orexin receptor antagonist with Ki = 0.95 nM. |
|
| DC9465 | Pitolisant (hydrochloride) Featured | Pitolisant Hcl(BF2.649;Ciproxidine ) is a novel, potent, and selective nonimidazole inverse agonist at the recombinant human H3 receptor (Ki=0.16 nM). |
|
| DC11529 | Solriamfetol hydrochloride Featured | Solriamfetol hydrochloride (JZP-110, R-228060, ADX-N05, YKP-10A) is a norepinephrine-dopamine reuptake inhibitor that inhibits dopamine and norepinephrine transporter with IC50 of 2.9 and 4.4 uM, respectively. |
|
| DC5017 | Suvorexant Featured | Suvorexant (MK-4305) is a potent, selective, and orally bioavailable antagonist of OX1R and OX2R currently under clinical investigation as a novel therapy for insomnia.Suvorexant is an analytical reference standard categorized as a diazepane sedative.Formulations containing suvorexant show abuse potential similar to zolpidem in recreational polydrug users with a history of sedative and psychedelic drug use.2 Suvorexant is regulated as a Schedule IV compound in the United States. This product is intended for use in analytical forensic applications. |
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