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| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC7656 | Ro 61-8048 Featured | Ro 61-8048 is a potent and competitive kynurenine 3-hydroxylase inhibitor (Ki = 4.8 nM, IC50 = 37 nM). |
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| DC70126 | GSK 366 | A novel potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50 of 2.3 nM and 0.7 nM for human KMO and Pf-KMO, respectively. |
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| DC70127 | GSK 065 | A novel potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50 of 4.5 nM. |
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| DC70449 | GSK180 | GSK180 (GSK-180) is a potent and specific inhibitor of kynurenine-3-monooxygenase (KMO) with IC50 of 6 nM, shows negligible activity against other enzymes on the tryptophan pathway; inhibits the convertion of kynurenine to 3-hydroxykynurenine with IC50 of 2.0 uM in cell-based assays; prevents multiple organ failure in rodent models of acute pancreatitis. |
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