| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC11823 | BMS-929075 | A highly potent, selective, orally bioavailable HCV NS5B polymerase inhibitor with IC50 of 9, 4, and 18 nM for GT1a, GT1b, and GT1b-C316N mutant in HCV replicon assay, respectively. |
|
| DC11825 | MK-8876 | A novel, broadly acting non-nucleoside inhibitor of HCV NS5B polymerase with IC50 of 3 nM and 2 nM for GT1b and GT2a, respectively. |
|
| DC11731 | Ruzasvir | A potent, pan-genotype HCV NS5A inhibitor with replicon EC90 of 0.003, 0.016, 0.067, 0.036, 0.007, and 0.007 nM for GT1a, GT1a L31V, GT1a Y93H, GT2b, GT3a, and Gt4a, respectively.. |
|
| DC7541 | Balapiravir | Balapiravir (R1626, Ro 4588161) is the prodrug of a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R1479, RG1479). |
|
| DC5077 | Boceprevir(EBP 520; SCH 503034 ) Featured | Boceprevir(EBP 520; SCH 503034 ) is useful for Anti HCV. |
|
| DC7387 | Clemizole Hydrochloride Featured | Clemizole is a H1 histamine receptor antagonist.Recently, researchers have identified that clemizole hydrochloride can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication. |
|
| DC8832 | Clemizole (free base) Featured | Clemizole is a H1 histamine receptor antagonist.Recently, researchers have identified that clemizole hydrochloride can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication. |
|
| DC11081 | Coblopasvir | Coblopasvir (KW136, KW-136) is a novel HCV NS5A inhibitor under development for treatment of HCV infection.. |
|
| DC9510 | CTS-1027 | CTS-1027 is a potent small molecule inhibitor of MMPs(IC50=0.4 nM/0.6 nM for MMP2/MMP13); >1,000 fold selectivity over MMP1. |
|
| DC7394 | Daclatasvir dihydrochloride (BMS-790052) Featured | Daclatasvir (BMS-790052) is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture. |
|
| DC8238 | Danoprevir Featured | Danoprevir is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM, inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A. |
|
| DC10818 | ABT-493(Glecaprevir) Featured | Glecaprevir is a novel HCV NS3/4A protease inhibitor, with IC50 values ranging from 3.5 to 11.3 nM. |
|
| DC11494 | INX-08189 | INX-08189 is a phosphoramidate prodrug of O-6-methyl-2-C-methyl guanosine, potent inhibitor of HCV NS5B polymerase with IC50 of 10 nM in replicon assay. |
|
| DC7609 | Isatoribine | Isatoribine is a selective agonist of TLR7 |
|
| DC11419 | Merimepodib Featured | Merimepodib(VX-497) is a novel noncompetitive inhibitor of IMPDH (Inosine monophosphate dehydrogenase). |
|
| DC8178 | Beclabuvir(BMS-791325) | non-nucleoside inhibitor of the NS5B |
|
| DC8183 | Paritaprevir(Veruprevir ABT-450) Featured | NS3/4A protease inhibitor |
|
| DC10728 | Pibrentasvir(ABT-530) Featured | Pibrentasvir is a novel and pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with EC50s ranging from 1.4 to 5.0 pM against HCV replicons containing NS5A from genotypes 1 to 6. |
|
| DC4121 | PSI6130 Featured | PSI-6130(R 1656) is a Hepatitis C Virus Nucleoside Inhibitor. PSI-6130(R 1656) is useful for Antiviral agents. |
|
| DC9462 | R-7128(Mericitabine) Featured | R-7128(Mericitabine) is a selective nucleoside analog inhibitor of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, with activity across all HCV genotypes. |
|
| DC8190 | Ravidasvir hydrochloride (PPI-668) Featured | Ravidasvir(PPI-668) is a NS5A Inhibitor. |
|
| DC8612 | Simeprevir(TMC-435) | Simeprevir (TMC 435350) is a potent inhibitor of HCV NS3/4A protease (Ki = 0.36 nM) and viral replication (replicon EC50 = 7.8 nM). |
|
| DC1008 | Telaprevir (VX-950) Featured | Telaprevir (VX-950) is an HCV NS3-4A serine protease inhibitor with IC50 of 0.35 μM. |
|
| DC10104 | VX222(Lomibuvir) Featured | VCH-222(Lomibuvir) is a novel, potent and selective inhibitor of HCV polymerase with IC50 of 0.94-1.2 μM, 15.3-fold less effective for mutant M423T, and 108-fold less effective for mutant I482L. |
|
| DC9751 | Velpatasvir(GS5816) Featured | Velpatasvir(GS-5816) is a potent and selective Hepatitis C virus NS5A inhibitor. |
|
