Cat. No. | Product name | CAS No. |
DC9962 |
YM-58483
Featured
YM-58483 is the first selective and potent inhibitor of CRAC channels and subsequent Ca2+ signals. |
223499-30-7 |
DC40200 |
RO2959 monohydrochloride
RO2959 monohydrochloride is a potent and selective CRAC channel inhibitor with an IC50 of 402 nM. RO2959 monohydrochloride is a potent blocker of store operated calcium entry (SOCE) mediated by Orai1/Stim1 channels with an IC50 of 25 nM. RO2959 monohydrochloride is also a potent inhibitor of human IL-2 production, and potently blocks T cell receptor triggered gene expression and T cell functional pathways. |
2309172-44-7 |
DC70467 |
GSK-5498A
GSK-5498A is a potent, selective small molecule blocker of Calcium-Release Activated Calcium (CRAC) channel with IC50 of 1 uM; completely inhibits calcium influx through CRAC channels, inhibits mediator release from mast cells, and pro-inflammatory cytokine release from T-cells from multiple human and rat preparations. |
1253186-49-0 |