DC11514 |
Atogepant |
A potent, selective and orally available CGRP receptor antagonist for the prevention of migraine.
Migraine. |
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DC11239 |
AMG-333
Featured
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AMG 333 is a potent and highly selective TRPM8 antagonist with an IC50 of 13 nM. |
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DC8323 |
Eletriptan HBr
Featured
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Eletriptan HBr is an orally active, selective 5-HT1B/1D receptor agonist. |
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DC9398 |
MK-0974 |
MK-0974(Telcagepant) is a highly potent, selective, and orally bioavailable CGRP receptor antagonist with Ki values of 0.77 nM and 1.2 nM for human and rhesus CGRP receptors respectively; displays >1500-fold lower affinity for the canine and rat receptors |
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