Cat. No. | Product name | CAS No. |
DC5060 |
(+)PD 128907
(+)PD 128907 is a potent D3 dopamine receptor agonist (Ki = 2.3 nM). Displays 18 - 200-fold selectivity over other dopamine receptor subtypes. |
300576-59-4 |
DCZ-059 |
L-Stepholidine
Featured
Stepholidine s a naturally occurring chemical compound found in the herb Stephania intermedia. Stepholidine is a dual D2 receptor antagonist and D1 receptor agonist, and has shown antipsychotic activity in animal studies. |
16562-13-3 |
DC11974 |
L 741742 hydrochloride
A potent and highly selective D4 dopamine receptor antagonist with Ki of 3.5 nM, >200-fold selectivity over D2 and D3 receptors. |
874882-93-6 |
DC12015 |
SKF 83566 hydrobromide
A potent, selective dopamine D1 receptor antagonist with Ki of 0.56 nM. |
108179-91-5 |
DC11973 |
A-412997
A potent, selective dopamine D4 receptor agonist with Ki of 12.1 and 7.9 nM for rat and human D4 receptors, respectively. |
1347744-96-0 |
DC11667 |
PF-592379
A potent, selective, orally active agonist of dopamine D3 receptor with EC50 of 21 nM. |
710655-15-5 |
DC11972 |
PNU 96415E
A potential antipsychotic agent that binds selectively to D4 and 5-HT2A receptors with Ki of 3.0 and 5.8 nM, respectively. |
170856-41-4 |
DC8713 |
Azaperone
Azaperone acts as a dopamine antagonist but also has some antihistaminic and anticholinergic properties. Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic drug with sedative and antiemetic effects, which is used mainly as a tranquilizer in |
1649-18-9 |
DC8883 |
BP897
Featured
BP897 is a partially selective D3 dopamine receptor agonist. |
314776-92-6 |
DC8286 |
Brexpiprazole(OPC34712)
Featured
Brexpiprazole is a novel D2 dopamine partial agonist. |
913611-97-9 |
DC9423 |
Cabergoline
Cabergoline, an ergot derivative, is a potent dopamine receptor agonist on D2 receptors. |
81409-90-7 |
DC8054 |
Cariprazine (RGH-188)
Featured
Cariprazine (RGH-188) is a novel putative antipsychotic drug that exerts partial agonism at dopamine D2/D3 receptors, with preferential binding to D3 receptors, and partial agonism at serotonin 5-HT1A receptors. |
839712-12-8 |
DC7991 |
8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e](1,4)diazepine N-oxide
Featured
Clozapine N-oxide is a major metabolite of Clozapine noted to decrease SR-2A (5-HT2 serotonin receptor) density in vitro. |
34233-69-7 |
DC9067 |
Clozapine
Clozapine(HF 1854) is a 5-HT2A/2C and dopamine receptor blocker with Ki values of 21, 170, 170, 230 and 330 nM for D4, D3, D1, D2 and D5 receptors respectively. |
5786-21-0 |
DC11124 |
D-520
D-520 is a potent, multifunctional D2/D3 agonist with Ki of 41.8 /0.35 nM, modulates aggregation of alpha-synuclein (αSN) and reduces toxicity of preformed aggregates of αSN. |
1619269-47-4 |
DC11103 |
Tavapadon
Featured
Tavapadon is a potent, orally-bioavailable, selective partial agonist of the dopamine D1 and D5 receptors. |
1643489-24-0 |
DC9164 |
Flupenthixol dihydrochloride
Featured
Flupenthixol dihydrochloride is a typical antipsychotic of the thioxanthene class that acts as an antagonist at dopamine D2 receptors (Ki = 0.38 nM) and an inverse agonist at serotonin 5-HT2A receptors (Ki = 7 nM).1 It has also been identified as an inhib |
51529-01-2 |
DC11165 |
MLS6585
MLS6585 is a novel positive allosteric modulator of the D1 dopamine receptor, potentiatse dopamine-stimulated G-protein- and β-arrestin-mediated signaling and increase the affinity of dopamine for the D1 receptor with low micromolar potencies.. |
389080-71-1 |
DC12351 |
NMI 8739
NMI 8739 is a dopamine D2 autoreceptor agonist, which is an amine conjugate of the DHA carrier and the neurotransmitter dopamine. |
129024-87-9 |
DC9134 |
Paliperidone
Paliperidone (9-hydroxyrisperidone) is a dopamine antagonist of the atypical antipsychotic class of medications. |
144598-75-4 |
DC9675 |
Pardoprunox.HCl(SLV-308)
Featured
Pardoprunox hydrochloride is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A receptor (pKi = 8.5) full agonist. |
269718-83-4 |
DC6911 |
pardoprunox (SLV308)
Featured
Pardoprunox(SLV-308) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist; D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist (IA = 50% and 67%, respectively) and 5-HT1A receptor (pKi = 8.5) full agonist (IA |
269718-84-5 |