| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC10824 | ARN-3236 Featured | ARN-3236 is potent, orally active and selective SIK2 inhibitor. ARN-3236 inhibited the growth of 10 ovarian cancer cell lines at an IC50 of 0.8 to 2.6 μmol/L. |
|
| DC10778 | YKL-06-061 Featured | YKL-06-061 is a potent and selective SIK (salt-inducible kinase) inhibitor. |
|
| DC46043 | MRIA9 | MRIA9 is an ATP-competitive, pan Salt-Inducible kinase (SIK) and PAK2/3 inhibitor, with IC50 values of 516 nM, 180 nM and 127 nM for SIK1, SIK2 and SIK3, respectively. |
|
| DC46639 | WH-4-025 Featured | WH-4-025 is a Salt-inducible kinase (SIK) inhibitor (WO2016023014 A2). |
|
| DC72558 | GLPG3970 Featured | GLPG3970 (compound 88) is a first-in-class SIK2/SIK3 inhibitor. GLPG3970 can be used for the research of inflammation and autoimmune disease. |
|
| DC73147 | GLPG3312 | GLPG3312 is a potent and selective pan-SIK inhibitor with IC50 of 2.0/0.7/0.6 nM for SIK1/SIK2/SIK3, respectively. |
|
| DC73148 | JRD-SIK1/2i-4 | JRD-SIK1/2i-4 is a potent, highly selective SIK1/2 inhibitor, modulates innate immune activation and suppress intestinal inflammation. |
|
| DC73149 | SK-124 | SK-124 (SK124) is a potent, selective, orally active SIK2/SIK3 inhibitor with IC50 of 8.8/11.3 nM in cell-based NanoBRET assays, 15-fold selectivity versus SIK1. |
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