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| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC11704 | CFI-401870 | A potent, selective, orally active Mps1 (TTK) inhibitor with IC50 of 3.1 nM. |
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| DC11677 | CCT-271850 | A potent, selective, orally bioavailable Mps1 kinase inhibitor with IC50 of 11 nM. |
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| DC7072 | AZ3146 Featured | AZ3146 is a potent and selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50 = 35 nM); less potent to FAK, JNK1, JNK2, and Kit. |
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| DC9679 | BAY1217389 Featured | BAY1217389 is an orally bioavailable, selective inhibitor of the serine/threonine kinase monopolar spindle 1 (Mps1, TTK), with potential antineoplastic activity. |
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| DC7470 | MPI-0479605 Featured | MPI-0479605 is an ATP competitive and selective inhibitor of mitotic kinase Mps1 with IC50 of 1.8 nM, >40-fold selectivity over other kinases. |
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| DC8119 | Mps1-IN-2 Featured | Mps1-IN-2 is a potent Mps1 kianse inhibitor with IC50 value of 145 nM. |
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| DC5087 | Mps1-IN-1 | Mps1-IN-1 is a highly potent and selectibe Mpsl inhibitor with IC50 of 367 nM; >1000-fold selectivity relative to the 352 member kinase panel with the major exceptions of Alk and Ltk. |
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| DC7866 | NMS-P715 Featured | NMS-P715 is the first selective, ATP-competitive and orally bioavailable MPS1 small-molecule inhibitor(IC50=8 nM); selectively reduces cancer cell proliferation, leaving normal cells almost unaffected. |
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| DC28264 | TC-Mps1-12 | TC-Mps1-12 is a potent and selective monopolar spindle 1 (Mps1) inhibitor, with an IC50 of 6.4 nM. |
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| DC70063 | CFI-402257(luvixasertib) Featured | CFI-402257(luvixasertib) is a potent and selective Mps1/TTK kinase inhibitor with Ki of 0.1 nM and cellular Mps1 EC50 of 6.5 nM. |
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| DC73202 | SYL1073 | SYL1073 is a potent, selective and covalent Threonine tyrosine kinase (TTK) inhibitor with IC50 of of 16 nM. |
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