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| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC10187 | 666-15 Featured | 666-15 is a potent and selective CREB inhibitor with an IC50 of 81 nM. |
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| DC10654 | KG-501(Naphthol AS-E phosphate) Featured | KG-501 is a small molecule inhibitor of Aldolase, Histochemical substrate for alkaline phosphatases. |
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| DC7554 | SGC-CBP30 Featured | SGC-CBP30 is a potent CREBBP/EP300 inhibitor with IC50 of 21 nM and 38 nM, respectively. |
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| DC70208 | Artepillin C | Artepillin C (CREB-CRTC2 inhibitor APC) is an inhibitor of CREB/CRTC2 interaction (IC50=24.5 uM), dissociates the CREB/CRTC2 complex, directly binds to CREB with Kd of 3.2 uM.CREB-CRTC2 inhibitor APC inhibits CRTC2 interacting with CREB-ZIP and reduces acetyltransferase activity of CBP by binding with CREB protein directly.Artepillin C attenuated gluconeogenesis in primary hepatocytes, reduced glucose output from primary hepatocytes induced by glucagon, remarkably decreased the mRNA accumulation of G6pc, Pck1, and Pgc-1α induced by glucagon in primary hepatocytes.|Artepillin C could ameliorate hyperlipidemia in obese mice. |
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| DC73817 | ATF3W-aeg peptide Featured | ATF3W-aeg peptide is a selective, peptide inhibitor of activating transcription factor 3 (ATF3) with high affinity (Kd=151 nM), increases CCL4 expression levels in human macrophages. |
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