| DC8275 |
Apilimod
Featured
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Apilimod(STA 5326) is a potent IL-12/IL-23 inhibitor, IL-12 production in cultures of IFN-r/LPS–stimulated human PBMCs is strongly inhibited by STA-5326 with an IC50 of 10 nM. |
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| DC7922 |
APY0201
Featured
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APY0201 is a potent, highly selective PIKfyve kinase inhibitor. |
|
| DC7343 |
YM201636
Featured
|
YM201636 is a selective PIKfyve inhibitor with IC50 of 33 nM, less potent to p110α. |
|
| DC47381 |
MOMIPP
Featured
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MOMIPP, a macropinocytosis inducer, is a PIKfyve inhibitor. MOMIPP penetrates the blood-brain barrier (BBB). |
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| DC74271 |
HZX-02-059 |
HZX-02-059 is a PIKfyve and tubulin dual-target inhibitor with high affinity for PIKfyve (Kd=10.4 nM), HZX-02-059 is a potent methuosis inducer, shows both in vitro and in vivo anti-tumor activity against TNBC. |
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