| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC8275 | Apilimod Featured | Apilimod(STA 5326) is a potent IL-12/IL-23 inhibitor, IL-12 production in cultures of IFN-r/LPS–stimulated human PBMCs is strongly inhibited by STA-5326 with an IC50 of 10 nM. |
|
| DC7922 | APY0201 Featured | APY0201 is a potent, highly selective PIKfyve kinase inhibitor. |
|
| DC7343 | YM201636 Featured | YM201636 is a selective PIKfyve inhibitor with IC50 of 33 nM, less potent to p110α. |
|
| DC47381 | MOMIPP Featured | MOMIPP, a macropinocytosis inducer, is a PIKfyve inhibitor. MOMIPP penetrates the blood-brain barrier (BBB). |
|
| DC74271 | HZX-02-059 | HZX-02-059 is a PIKfyve and tubulin dual-target inhibitor with high affinity for PIKfyve (Kd=10.4 nM), HZX-02-059 is a potent methuosis inducer, shows both in vitro and in vivo anti-tumor activity against TNBC. |
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