| DC11563 |
E3 Ligand-Linker Conjugate 2 |
An E3 ligand- Linker Conjugate for PROTAC.. |
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| DC11575 |
E3 Ligand-Linker Conjugate 9
Featured
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An E3 ligase ligand-linker conjugate for PROTAC. |
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| DC11572 |
E3 Ligand-Linker Conjugate 6
Featured
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An E3 ligase ligand-linker conjugate for PROTAC.. |
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| DC11573 |
E3 Ligand-Linker Conjugate 7
Featured
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An E3 ligase ligand-linker conjugate for PROTAC.. |
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| DC11574 |
E3 Ligand-Linker Conjugate 8
Featured
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An E3 ligase ligand-linker conjugate for PROTAC.. |
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| DC11576 |
E3 Ligand-Linker Conjugate 10 |
An E3 ligase ligand-linker conjugate for PROTAC.. |
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| DC22869 |
E3 Ligand-Linker Conjugate 3(E3 Ligase Ligand-Linker Conjugates 19)
Featured
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An E3 ligase ligand-linker conjugate for PROTAC. |
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| DC11569 |
E3 Ligand-Linker Conjugate 4 |
An E3 ligase ligand-linker conjugate for PROTAC... |
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| DC11570 |
E3 Ligand-Linker Conjugate 5 |
E3 Ligand-Linker Conjugate 5 is an E3 ligase ligand-linker conjugate for PROTAC.. |
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| DC12141 |
E3 Ligase Ligand-Linker Conjugates 22
Featured
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E3 Ligase Ligand-Linker Conjugates 22 incorporates an E3 ligase ligand and a linker, can be used for the treatment of EZH2-mediated cancer. |
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| DC12092 |
E3 Ligase Ligand-Linker Conjugates 23 TFA |
E3 Ligase Ligand-Linker Conjugates 23 (TFA) is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology. |
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| DC12181 |
E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate |
E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology. |
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| DC28314 |
Aminooxy-PEG2-azide |
Aminooxy-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Aminooxy-PEG2-azide is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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| DC28514 |
THP-PEG6-OH |
THP-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. THP-PEG6-OH is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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| DC28580 |
NH2-PEG5-OH |
NH2-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH2-PEG5-OH is also a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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| DC28654 |
NH2-PEG6-Boc
Featured
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NH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH2-PEG6-Boc is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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| DC28662 |
Amino-PEG4-CH2COOH |
Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Amino-PEG4-CH2COOH is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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| DC28664 |
Azido-PEG6-alcohol |
Azido-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG6-alcohol is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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| DC28686 |
Azido-PEG4-C2-acid |
Azido-PEG4-C2-acid a PEG-based PROTAC linker can be used in the synthesis of vRucaparib-TP4. Azido-PEG4-C2-acid is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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| DC29016 |
NH2-PEG2-C2-Boc |
NH2-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH2-PEG2-C2-Boc is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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| DC29019 |
N3-PEG3-CH2CH2COOH |
N3-PEG3-CH2CH2COOH a PEG-based PROTAC linker can be used in the synthesis of BI-3663, BI-4216 and BI-0319. Azido-PEG3-acid is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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| DC29164 |
Amino-PEG4-alcohol |
Amino-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Amino-PEG4-alcohol is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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| DC29204 |
Boc-NH-PEG4-CH2CH2COOH |
Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. Boc-NH-PEG4-CH2CH2COOH is also a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC). |
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| DC33611 |
PSMA-617 Linker
Featured
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Vipivotide tetraxetan Ligand-Linker Conjugate (PSMA-617 Ligand-Linker Conjugate) is composed of a linker and Glutamate-urea-Lysine, can be used to synthesize Vipivotide tetraxetan (PSMA-617). Glutamate-urea-Lysine is is the selective pharmacophore to bind to prostate specific membrane antigen (PSMA).
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| DC39625 |
(S,R,S)-AHPC-PEG4-NH2 hydrochloride
Featured
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VH 032 Linker 2 is a derivative of the proteolysis-targeting chimera technology (PROTAC) building block VHL ligand 1. |
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| DC40302 |
Lenalidomide-C5-NH2 hydrochloride |
Lenalidomide-C5-NH2 hydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-NH2 can be connected to the ligand for protein by a linker to form PROTACs, such as MDM2 PROTAC degrader. |
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| DC40349 |
VHL Ligand-Linker Conjugates 15 |
VHL Ligand-Linker Conjugates 15 incorporates an VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. VHL Ligand-Linker Conjugates 15 can be used to design PROTACs. |
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| DC40421 |
Pomalidomide-amido-PEG3-C2-NH2 |
Pomalidomide-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 22) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology. |
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| DC40422 |
Pomalidomide-amido-C1-Br |
Pomalidomide-amido-C1-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker. Pomalidomide-amido-C1-Br can be used to design a B-Raf PROTAC degrader PROTAC B-Raf degrader 1. PROTAC B-Raf degrader 1 has anti-cancer activity.
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| DC40428 |
Pomalidomide 4'-alkylC5-acid |
Pomalidomide 4'-alkylC5-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a PEG linker used in PROTAC technology. |
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