Cat. No. | Product name | CAS No. |
DC10625 |
(+)-Bicuculline
Featured
(+)-Bicuculline is a competitive antagonist of GABAA receptors with IC50 of 2 μM, also blocks Ca(2+)-activated potassium channels. |
485-49-4 |
DC9450 |
(R)-Baclofen
(R)-Baclofen(STX209) is a selective GABAB receptor agonist. |
69308-37-8 |
DC9026 |
Afloqualone
Afloqualone is a agonist of GABA receptor . |
56287-74-2 |
DC9764 |
Afoxolaner
Featured
Afoxolaner is an isoxazoline that inhibits insect and acarine ligand-gated chloride channels, in particular those gated by the neurotransmitter gamma-aminobutyric acid (GABA), blocking pre and post synaptic transfer of chloride ions across cell membranes. |
1093861-60-9 |
DC10311 |
Allopregnanolone
Featured
Allopregnanolone is a progesterone metabolite. Allopregnanolone is an allosteric modulator of the GABA receptor. |
516-54-1 |
DC11657 |
PPT
An allosteric GABAA receptor modulator that strongly suppresses GABA-induced chloride currents... |
263717-53-9 |
DC8971 |
Baclofen
Baclofen is a gamma-amino-butyric acid (GABA) derivative used as a skeletal muscle relaxant. |
1134-47-0 |
DC9935 |
Basmisanil(RG1662)
Featured
Basmisanil is a highly selective inverse agonist/negative allosteric modulator of α5 subunit-containing GABAA receptors which is under development by Roche for the treatment of cognitive impairment associated with Down syndrome. |
1159600-41-5 |
DC10843 |
CGP 52432
Featured
CGP 52432 is a potent, selective GABAB receptor antagonist (IC50 = 85 nM). |
139667-74-6 |
DC12100 |
Cirsimaritin
Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors, with antidepressant, anxiolytic and antinociceptive activities. |
6601-62-3 |
DC7009 |
CNS-7056
CNS 7056 is a new short-acting sedative/anaesthetic that acts on GABAA receptors in the brain. |
308242-62-8 |
DC8706 |
Emamectin Benzoate
Emamectin Benzoate works as a chloride channel activator by binding gamma aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropods. |
155569-91-8 |
DC8821 |
Etifoxine Hydrochloride
Featured
Etifoxine Hydrochloride is a psychotropic agent with anxiolytic and anticonvulsant activity. Etifoxine Hydrochloride is an activator of GABAA R β2 and GABAA R β3. |
56776-32-0 |
DC11309 |
Fipronil
Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 and 1,600 nM for cockroach and rat receptors, respectively). |
120068-37-3 |
DC9451 |
Flumazenil
Flumazenil(Ro 15-1788) is a benzodiazepine antagonist, non-selective for α1, α2, α3 or α5-containing GABAA receptors. |
78755-81-4 |
DC10158 |
Fluralaner
Featured
Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels. |
864731-61-3 |
DC9381 |
Gabapentin (hydrochloride)
Gabapentin (Neurontin) is a pharmaceutical drug, specifically a GABA analog. |
60142-95-2 |
DC8954 |
Gabapentin
Featured
Gabapentin (Neurontin) is a pharmaceutical drug, specifically a GABA analog. It was originally developed to treat epilepsy, and currently is also used to relieve neuropathic pain. |
60142-96-3 |
DC11090 |
GR3027
Featured
GR3027 (Golexanolone) is a GABA-A receptor modulating steroid antagonist that selectively antagonizes the enhanced activation of GABAA receptors by neurosteroids such as allopregnanolone and THDOC. |
2089238-18-4 |
DC11118 |
HZ-166
HZ-166 (HZ166) is a GABAA receptor subtype-selective benzodiazepine site ligand with preferential activity at α2- and α3-GABA(A) receptors. |
612527-56-7 |
DC4137 |
Indiplon
Featured
Indiplon is a novel sedative-hypnotic recently approved for the treatment of insomnia. |
325715-02-4 |
DC10853 |
LAU159
Featured
LAU159 is a novelα6β3γ2 GABAA receptor inhibitor. |
2055050-87-6 |