Cat. No. | Product name | CAS No. |
DC5114 |
Apixaban (BMS 562247-01)
Featured
Apixaban is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively. |
503612-47-3 |
DC8004 |
AZD6482
Featured
AZD6482 is a PI3Kβ inhibitor with IC50 of 10 nM, 8-, 87- and 109-fold more selective to PI3Kβ than PI3Kδ, PI3Kα and PI3Kγ. |
1173900-33-8 |
DC7373 |
Betrixaban
Featured
Betrixaban (PRT-054021) is a highly potent, selective, and orally efficacious factor Xa inhibitor with IC50 of 1.2 nM(inhibition of Factor 10a). |
330942-05-7 |
DCAPI1112 |
BIBR 953(Dabigatran)
Featured
BIBR 953 (Dabigatran, Pradaxa) is a highly selective, reversible, and potent thrombin inhibitor and is orally available as the prodrug, dabigatran etexilate. |
211914-51-1 |
DC1010 |
BIBR-1048 (Dabigatran etexilate)
Featured
BIBR-1048 (Dabigatran) is an anticoagulant from the class of the direct thrombin inhibitors. |
211915-06-9 |
DC11923 |
BMS-986120
BMS-986120 (BMS986120) is a potent, selective, orally bioavailable, and reversible PAR4 antagonist with Kd of 0.098 nM for human PAR4. |
1478712-37-6 |
DC7005 |
Cangrelor free acid
Featured
Cangrelor is a P2Y12 inhibitor, and was approved in June 2015 as an antiplatelet drug for intravenous application. Cangrelor is a high-affinity, reversible inhibitor of P2Y12 receptors that causes almost complete inhibition of ADP-induced platelet aggregate. It is a modified ATP derivative stable to enzymatic degradation. It does not require metabolic conversion to an active metabolite. This allows cangrelor’s immediate effect after infusion, and the therapeutic effects can be maintained with continuous infusion. |
163706-06-7 |
DC3147 |
Clopidogrel hydrogensulfate
Clopidogrel (Plavix) is an oral, thienopyridine class antiplatelet agent. |
120202-66-6 |
DCAPI1417 |
Clopidogrel
Clopidogrel is an irreversible inhibitor of the P2Y12 receptor, which is responsible for initiating signal transduction via a GPCR. The signal cascade initiates platelet aggregation and thus clopidogrel has the effect of “thinning” the blood. |
113665-84-2 |
DC8913 |
Dabigatran etexilate mesylate
Featured
Dabigatran etexilate mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM. |
872728-81-9 |
DC8533 |
E5555 hydrobromide
E5555 shows potent inhibitory effects on human platelet aggregation induced by thrombin and TRAP with IC values of 0.064 and 0.031 μM respectively. |
474550-69-1 |
DC8305 |
Edoxaban
Featured
Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention |
480449-71-6 |
DC8793 |
Edoxaban tosylate monohydrate
Featured
Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention |
1229194-11-9 |
DC7772 |
Elinogrel
Elinogrel is a reversible P2Y12 receptor antagonist for the treatment of acute coronary syndrome and prevention of secondary thrombotic events. |
936500-94-6 |
DC9443 |
Otamixaban
Otamixaban(FXV673) is a potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa. |
193153-04-7 |
DC10500 |
PF-06282999
Featured
PF-06282999 is a potent and selective myeloperoxidase inhibitor which is potential useful for the treatment of cardiovascular diseases. |
1435467-37-0 |
DC5108 |
BAY 59-7939 (Rivaroxaban)
Featured
Rivaroxaban (Xarelto; BAY 59-7939) is a novel, oral, direct Factor Xa (FXa) inhibitor in late-stage development for the prevention and treatment of thromboembolic disorders. |
366789-02-8 |
DC1101 |
Ticagrelor (Brilinta,AZD6140)
Featured
Ticagrelor is the first reversibly binding oral P2Y12 receptor antagonist, also inhibits CYP2C9 and 4-hydroxylation with IC50 of 10.5 μM and 8.2 μM respectively. |
274693-27-5 |
DC9489 |
Tirofiban (hydrochloride monohydrate)
Featured
Tirofiban hydrochloride monohydrate is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist |
150915-40-5 |
DC7327 |
Tirofiban(L700462;MK383)
Featured
Tirofiban(L700462;MK383) is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist. |
144494-65-5 |
DC8860 |
Vorapaxar
Featured
Vorapaxar (SCH 530348) is a potent and orally active thrombin receptor (PAR-1) antagonist with Ki of 8.1 nM. |
618385-01-6 |