| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC11564 | CDK9-PROTAC | A heterobifunctional small molecule PROTAC capable of cereblon mediated proteasomal degradation of CDK9. |
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| DC11590 | Homo-PROTAC pVHL30 degrader 1 Featured | CM-11 is a homo-PROTAC, bivalent small-molecule dimerizer of the VHL E3 ubiquitin ligase to induce self-degradation. |
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| DC11867 | TBK1 PROTAC 1 | A novel potent, selective TBK1 PROTAC with DC50 of 12 nM, selectively degrades TBK1 with excellent selectivity against a related kinase IKKε. |
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| DC11562 | Sirt2-PROTAC-1 | A novel SirReal-based PROTAC that induces isotype-selective Sirt2 degradation (IC50=0.25 uM).. |
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| DC11591 | Bis-PEG4-acid | A PEG linker for PROTAC.. |
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| DC11592 | Bis-PEG5-acid | A PEG linker for PROTAC.. |
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| DC11593 | Bis-PEG6-acid | A PEG linker for PROTAC.. |
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| DC11583 | N3-PEG2-CH2COOH | A PEG2 linker for PROTAC.. |
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| DC11577 | N3-PEG3-CH2COOH | A PEG3 linker for PROTAC.. |
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| DC11582 | N3-PEG4-CH2COOH | A PEG4 linker for PROTAC.. |
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| DC11578 | VHL Ligand 3 Featured | A VHL ligand for PROTAC.. |
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| DC11581 | VHL Ligand 4 | A VHL ligand for PROTAC.. |
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| DC11580 | VHL-2 | A VHL ligand for PROTAC.. |
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| DC12702 | A1874 Featured | A1874 (A-1874) is a nutlin-based and BRD4-degrading PROTAC with DC50 of 32 nM (induce BRD4 degradation in cells). |
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| DCAPI1328 | Alprostadil(Caverject) Featured | Alprostadil(Caverject) is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases. |
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| DC11563 | E3 Ligand-Linker Conjugate 2 | An E3 ligand- Linker Conjugate for PROTAC.. |
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| DC11575 | E3 Ligand-Linker Conjugate 9 Featured | An E3 ligase ligand-linker conjugate for PROTAC. |
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| DC11572 | E3 Ligand-Linker Conjugate 6 Featured | An E3 ligase ligand-linker conjugate for PROTAC.. |
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| DC11573 | E3 Ligand-Linker Conjugate 7 Featured | An E3 ligase ligand-linker conjugate for PROTAC.. |
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| DC11574 | E3 Ligand-Linker Conjugate 8 Featured | An E3 ligase ligand-linker conjugate for PROTAC.. |
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| DC11576 | E3 Ligand-Linker Conjugate 10 | An E3 ligase ligand-linker conjugate for PROTAC.. |
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| DC22869 | E3 Ligand-Linker Conjugate 3(E3 Ligase Ligand-Linker Conjugates 19) Featured | An E3 ligase ligand-linker conjugate for PROTAC. |
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| DC11569 | E3 Ligand-Linker Conjugate 4 | An E3 ligase ligand-linker conjugate for PROTAC... |
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| DC10334 | ARV-771 Featured | ARV-771 is a potent bromodomain and extra-terminal (BET) proteins degrader with Kd values of 4.7, 7.6, 7.6 nM against bromodomain 2, 3 and 4, respectively. |
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| DC12024 | ARV-825 Featured | ARV-825 is a BRD4 Inhibitor based on PROTAC technology. ARV-825 binds to BD1 and BD2 of BRD4 with Kds of 90 and 28 nM, respectively. |
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| DC11566 | BETd-260 Featured | BETd-260 (ZBC260, BETd260) is a novel PROTAC BET degrader that tether HJB97 to a ligand for the E3 ubiquitin ligase VHL. |
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| DC11567 | BETd-260 trifluoroacetate | BETd-260 trifluoroacetate (ZBC260, BETd 260 TFA) is a novel PROTAC BET degrader that tether HJB97 to a ligand for the E3 ubiquitin ligase VHL. |
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| DC10997 | BRD4 degrader AT1 | BRD4 degrader AT1 is a highly selective Brd4 degrader based on PROTAC technology, with a Kd of 44 nM for Brd4BD2 in cells. |
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| DC12380 | BSJ-03-123 Featured | BSJ-03-123 is a potent, CDK6-selective small-molecule degrader (PROTAC) that uniquely enables rapid pharmacological interrogation of CDK6-dependent functions. |
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| DC11065 | BTK PROTAC 10 | BTK PROTAC 10 is a novel potent PROTAC for BTK with DC50 of 1.1 nM in cultured Ramos cells. |
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