| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC11982 | CX815 | A novel potent, selective CXCR2 inhibitor with IC50 of 0.4 nM. |
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| DC11981 | CX4152 | A novel potent, selective CXCR2 inhibitor with IC50 of 7.6 nM. |
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| DC11743 | BMS-681 | A potent and orally bioavailable dual antagonist of CCR2 and CCR5 with binding IC50 of 0.7 nM and 2.4 nM, respectively. |
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| DC11699 | VUF11403 | A potent CXCR7 (ACKR3) agonist.. |
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| DC11976 | SX-576 | A potent, equipotent CXCR1 and CXCR2 antagonist with IC50 of 31 nM and 21 nM, respectively. |
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| DC11979 | SB 332235 | A potent, selective and competitive CXCR2 inhibitor that selectively inhibits CXCR2-mediated recruitment of β-arrestin-2 with pKi of 8.92. |
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| DC11700 | Chalcone 4 hydrate | A potent, selective inhibitor of CXCL12 binding to CXCR4 and CXCR7 with IC50 of 200 nM. |
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| DC11745 | BMS-22 | A potent, selective, allosteric CCR2 antagonist with binding IC50 of 5.1 nM. |
|
| DC11744 | CCR2-RA-[R] | A potent, selective, allosteric CCR2 antagonist with IC50 of 103 nM.. |
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| DC11746 | JNJ-27141491 | A potent, selective, noncompetitive, orally active CCR2 antagonist with IC50 of 172 nM. |
|
| DC11978 | SB 265610 Featured | SB-265610 is a selective, competitive, nonpeptide and allosteric CXCR2 antagonist. |
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| DC11983 | CX797 | A potent, specfic CXCR2 antagonist that inhibits IL8 down-regulation of forskolin-induced cAMP with IC50 of 7.79 uM. |
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| DC11977 | SX-517 | A potent, specific, noncompetitive dual CXCR1 and CXCR2 antagonist with IC50 of 38 nM (vs. CXCL1) and 36 nM (vs. CXCL8), respectively. |
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| DC11698 | α-NETA | A small molecule CMKLR1 antagonist that inhibits chemerin-stimulated β-arrestin2 association with CMKLR1 (EC50=9.7 nM). |
|
| DC11686 | (R)-CCX-777 | A small-molecule partial agonist of CXCR7 (ACKR3).. |
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| DC11687 | (S)-CCX-777 | A small-molecule partial agonist of CXCR7 (ACKR3).. |
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| DC11685 | CCX-777 | A small-molecule partial agonist of CXCR7 (ACKR3).. |
|
| DC5056 | AMD3465 Featured | AMD3465 is a Potent, selective CXCR4 antagonist; exhibits 8-fold higher affinity than AMD 3100 (Cat.No. 3299). Inhibits SDF-1α-ligand binding (Ki = 41.7 nM). |
|
| DC9878 | ATI-2341 | ATI-2341, pepducin targeting the C-X-C chemokine receptor type 4 (CXCR4), is an allosteric agonist activating the inhibitory heterotrimeric G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization. |
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| DC11147 | AZ084 | AZ084 (AZ-084) is a potent, selective, allosteric, orally available CCR8 antagonist with Ki of 0.9 nM. |
|
| DC11975 | AZ 10397767 | AZ10397767 is a potent, selective CXCR2 inhibitor that inhibits CXCL8 binding to CXCR2 with pIC50 of 9.0. |
|
| DC10724 | AZD2098 Featured | AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor, used for asthma research. |
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| DC10773 | AZD5069 Featured | AZD-5069 is a potent and selective CXCR2 antagonist with the potential to inhibit neutrophil migration into the airways in patients with COPD. |
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| DC11003 | BL5923 | BL5923 (BL-5923) is a potent, highly specific, orally available inhibitor of CCR1 with IC50 of 20.4 and 22.8 nM for human and mouse CCR1, resepctively. |
|
| DC7675 | BX-471（ZK 811752） Featured | BX471 is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1); exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. |
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| DC11204 | CCR6 inhibitor 35 | CCR6 inhibitor 35 is a potent and selective CCR6 inhibitor with IC50 of 6.0 nM (hCCR6). |
|
| DC10206 | CCX140 | CCX140 is a potent CCR2 antagonist. |
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| DC11980 | CX 4338 | CX 4338 (CX4338, CX-4338) is a potent, selective CXCR2 inhibitor that selectively inhibits CXCR2-mediated recruitment of β-arrestin-2 with IC50 of 6.3 uM. |
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| DC10203 | CXCR2-IN-1 | CXCR2-IN-1 is a central nervous system penetrant CXCR2 antagonists with a pIC50 of 9.3. |
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| DC9689 | Danirixin (GSK1325756) Featured | Danirixin(GSK1325756) is a selective CXCR2 antagonist. |
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