Cat. No. | Product name | CAS No. |
DC7818 |
(-)Blebbistatin
Featured
(-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM, does not inhibit myosin light chain kinase, inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. |
856925-71-8 |
DC11524 |
Mavacamten(MYK-461)
Featured
Mavacamten(MYK-461)is a small molecule that reduces contractility by decreasing the ATPase activity of the cardiac myosin heavy chain. |
1642288-47-8 |
DC28106 |
ML-9 Free Base
ML-9 (Free Base) is a selective and potent inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK) and stromal interaction molecule 1 (STIM1) activity. ML-9 (Free Base) inhibits inhibits MLCK, PKA and PKC activity with Ki values of 4, 32 and 54 μM, respectively. ML-9 (Free Base) induces autophagy by stimulating autophagosome formation and inhibiting their degradation. |
110448-31-2 |
DC47557 |
Aficamten
Aficamten (CK-274) is a novel cardiac myosin inhibitor with an IC50 of 1.4 μM. Aficamten can be used for the research of hypertrophic cardiomyopathy (HCM). |
2364554-48-1 |
DC47558 |
MT-134
MT-134 is a SkMII-specific inhibitor and has excellent exposure in muscles. |