Home > Inhibitors & Agonists > Cytoskeleton/Cell Adhesion Molecules > Myosin
Cat. No. Product name CAS No.
DC7818 (-)Blebbistatin Featured

(-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM, does not inhibit myosin light chain kinase, inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly.

856925-71-8
DC11524 Mavacamten(MYK-461) Featured

Mavacamten(MYK-461)is a small molecule that reduces contractility by decreasing the ATPase activity of the cardiac myosin heavy chain.

1642288-47-8
DC28106 ML-9 Free Base

ML-9 (Free Base) is a selective and potent inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK) and stromal interaction molecule 1 (STIM1) activity. ML-9 (Free Base) inhibits inhibits MLCK, PKA and PKC activity with Ki values of 4, 32 and 54 μM, respectively. ML-9 (Free Base) induces autophagy by stimulating autophagosome formation and inhibiting their degradation.

110448-31-2
DC47557 Aficamten

Aficamten (CK-274) is a novel cardiac myosin inhibitor with an IC50 of 1.4 μM. Aficamten can be used for the research of hypertrophic cardiomyopathy (HCM).

2364554-48-1
DC47558 MT-134

MT-134 is a SkMII-specific inhibitor and has excellent exposure in muscles.

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