Cat. No. | Product name | CAS No. |
DC10037 |
4μ8C
Featured
4μ8C is a potent and selective IRE1 Rnase inhibitor with IC50 of 76 nM. |
14003-96-4 |
DC7358 |
APY29
Featured
APY29 is an allosteric modulator of IRE1α; inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity. |
1216665-49-4 |
DC10544 |
MKC3946
Featured
MKC3946 is a potent and soluble IRE1α inhibitor, used for cancer research. |
1093119-54-0 |
DC8413 |
STF-083010
Featured
STF-083010 is a specific IRE1α endonuclease inhibitor. |
307543-71-1 |
DC48263 |
IRE1α kinase-IN-6
IRE1α kinase-IN-6 is a potent IRE1α inhibitor with an IC50 value of 4.4 nM. |
2715123-88-7 |
DC70125 |
GSK2850163
A novel potent IRE1α-selective kinase inhibitor that inhibits both the kinase and RNase activities of IRE1α with IC50 of 20 nM and 200 nM, respectively; binds to pIRE1α and inhibits XBP 1 splicing; only weakly inhibits Ron (IC50= 4.4 uM) and FGFR1 V561M (IC50=17 uM) in a panel of 284 kinases. |
2121989-91-9 |