Home > Inhibitors & Agonists > Nuclear Receptor/Transcription Factor > IRE1
Cat. No. Product name CAS No.
DC10037 4μ8C Featured

4μ8C is a potent and selective IRE1 Rnase inhibitor with IC50 of 76 nM.

14003-96-4
DC7358 APY29 Featured

APY29 is an allosteric modulator of IRE1α; inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.

1216665-49-4
DC10544 MKC3946 Featured

MKC3946 is a potent and soluble IRE1α inhibitor, used for cancer research.

1093119-54-0
DC8413 STF-083010 Featured

STF-083010 is a specific IRE1α endonuclease inhibitor.

307543-71-1
DC48263 IRE1α kinase-IN-6

IRE1α kinase-IN-6 is a potent IRE1α inhibitor with an IC50 value of 4.4 nM.

2715123-88-7
DC70125 GSK2850163

A novel potent IRE1α-selective kinase inhibitor that inhibits both the kinase and RNase activities of IRE1α with IC50 of 20 nM and 200 nM, respectively; binds to pIRE1α and inhibits XBP 1 splicing; only weakly inhibits Ron (IC50= 4.4 uM) and FGFR1 V561M (IC50=17 uM) in a panel of 284 kinases.

2121989-91-9
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