| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC7494 | SB-242084 HCl Featured | 5-HT2C receptor antagonist that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2Breceptors respectively. Also displays selectivity over a range of other 5-HT, dopamine and adrenergic receptors. Brain penetrant; exerts anxiolytic-like activity. |
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| DC10537 | 8-OH-DPAT Featured | 8-OH-DPAT is a research chemical of the aminotetralin chemical class and has been widely used to study the function of the 5-HT1A receptor. |
|
| DC11523 | Landipirdine | A novel 5-HT receptor antagonist for the treatment of Parkinson's disease.. |
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| DC11903 | NBUMP | A potent, highly selective 5-HT1A receptor partial agonist with Ki of 0.1 nM, displays 460- and 260-fold selectivity for 5-HT1A over the α1-adrenergic and D2 receptors, respectively.. |
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| DC8284 | Almotriptan Malate(PNU180638) Featured | Almotriptan Malate is a 5-HT1B/1D-receptor agonist used to treat migraine. |
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| DC10234 | Alosetron Hydrochloride | Alosetron Hydrochloride is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. |
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| DC9147 | Aripiprazole | Aripiprazole(Abilify) is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM. |
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| DC11399 | AVN-492 Featured | AVN-492 is a very specific and highly-selective antagonist with picomolar affinity to 5-HT6R (Ki=91 pM). |
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| DCAPI1427 | Azasetron HCL | Azasetron Hydrochloride is a 5-HT3 receptor antagonist which is used as an anti-emetic. |
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| DC12290 | Befiradol hydrochloride (F 13640 hydrochloride) | Befiradol hydrochloride is a selective 5-HT1A receptor agonist. |
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| DC7087 | Blonanserin(AD-5423) | Blonanserin(AD-5423) is a D2/5-HT2 receptor antagonist, atypical antipsychotic. |
|
| DC7888 | BRL54443 | BRL 54443 is a 5-HT1E and 5-HT1F receptor agonist with pKi of 8.7 and 9.25, respectively, with a weak binding affinity for 5-HT1A, 5-HT1B, 5-HT1D receptors. |
|
| DC7091 | BRL-15572 dihydrochloride | BRL-15572 2Hcl is a 5-HT1D receptor antagonist with pKi of 7.9, also shows a considerable affinity at 5-HT1A and 5-HT2B receptors, exhibiting 60-fold selectivity over 5-HT1B receptor. |
|
| DC9317 | CP-809101 (hydrochloride) | CP-809101 Hcl is a potent and selective 5-HT2C receptor agonist with pEC50 of 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors respectively. |
|
| DC9323 | Dalasetron (Mesylate hydrate) | Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. |
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| DC8323 | Eletriptan HBr Featured | Eletriptan HBr is an orally active, selective 5-HT1B/1D receptor agonist. |
|
| DC11028 | EMD-281014 hydrochloride | EMD-281014 hydrochloride is a potent, highly selective 5-HT2A antagonist with Ki of 0.87 nM, displays little to no affinity for 5-HT2C receptors (Ki=557 nM), human D2 receptors and IKr channels. |
|
| DC11027 | EMD-281014 | EMD-281014 is a potent, highly selective 5-HT2A antagonist with Ki of 0.87 nM, displays little to no affinity for 5-HT2C receptors (Ki=557 nM), human D2 receptors and IKr channels. |
|
| DC9260 | Eptapirone Featured | Eptapirone (F-11,440) is a very potent and highly selective 5-HT1A receptor full agonist of the azapirone family. |
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| DC9080 | Granisetron HCl | Granisetron Hcl(BRL 43694A) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. |
|
| DC9705 | GSK163090 Featured | GSK163090 is a potent, selective, and orally active 5-HT1A/B/D receptor antagonist with pKi of 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3, respectively. |
|
| DCAPI1055 | Iloperidone (Fanapt) | Iloperidone (Fanapt) |
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| DC9006 | Lamotrigine | Lamotrigine(BW430C) is a novel anticonvulsant drug for inhibition of 5-HT and sodium channel. |
|
| DC7710 | Lasmiditan (COL-144; LY573144) Featured | Lasmiditan (COL-144; LY573144) is a high-affinity, highly selective 5-HT1F receptor agonist(Ki=2.1 nM), compared with Ki of 1043 nM and 1357 nM at the 5-HT(1B) and 5-HT(1D) receptors, respectively. |
|
| DC7583 | Idalopirdine(Lu-AE-58054) Featured | Lu AE58054 is an in-vitro potency and selectivity, in-vivo binding affinity and effect of the 5-HT(6)R antagonist with a Ki value of 0.83 nM. |
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| DC11422 | Lumateperone Tosylate Featured | Lumateperone Tosylate is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a SERT blocker (Ki = 61 nM). |
|
| DC3173 | Lurasidone HCl Featured | Lurasidone is an atypical antipsychotic, inhibits Dopamine D2, 5-HT2A, 5-HT7, 5-HT1A and noradrenaline α2C with IC50 of 1.68 nM, 2.03 nM, 0.495 nM, 6.75 nM and 10.8 nM, respectively. |
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| DC3174 | lurasidone | Lurasidone is a novel psychotropic agent that has been shown in studies of cloned human receptors to be an antagonist at the 5-HT2A receptor. |
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| DC7884 | LY310762 Featured | LY310762 is a 5-HT1D receptor antagonist with Ki of 249 nM, having a weaker affinity for 5-HT1B receptor. |
|
| DC10712 | LY334370 Featured | LY334370 is a selective 5-HT1F receptor agonist with a Ki of 1.6 nM. |
|
