| DC5060 |
(+)PD 128907 |
(+)PD 128907 is a potent D3 dopamine receptor agonist (Ki = 2.3 nM). Displays 18 - 200-fold selectivity over other dopamine receptor subtypes. |
|
| DCAPI1411 |
Bisoprolol Fumarate
Featured
|
(±)-Bisoprolol hemifumarate is a selective β1-AR adrenergic antagonist. Possesses β1/β2 selectivity of approximately 100-fold and a Kd of 2-3 nM at the β1-AR (β1 receptor). |
|
| DC10094 |
(±)-SLV319(Ibipinabant)
Featured
|
(±)-SLV 319 is a potent and selective CB1 receptor antagonist (Ki = 7.8 nM). Exhibits 1000-fold selectivity for CB1 over CB2 receptors. |
|
| DC10160 |
(1R,2S)-VU0155041 |
(1R,2S)-VU0155041, Cis regioisomer of VU0155041, is a partial mGluR4 agonist with an EC50 of 2.35 μM. |
-VU0155041 .gif)
|
| DC8964 |
Phenylephrine hydrochloride |
(R)-(-)-Phenylephrine hydrochloride is a phenylephrine (PE) and an α1-adrenoceptor agonist |
|
| DC11364 |
Levocetirizine；(R)-Cetirizine (hydrochloride) |
(R)-Cetirizine is the (R)-enantiomer of the histamine H1 receptor antagonist and second generation antihistamine cetirizine. |
|
| DC9137 |
Timolol Maleate
Featured
|
(S)-Timolol maleate, is a potent non-selective β-adrenergic receptor antagonist (Ki values are 1.97 and 2.0 nM for β1 and β2 receptor subtypes respectively). |
|
| DCZ-156 |
UR-144 |
>98%,Standard References |
|
| DCZ-059 |
L-Stepholidine
Featured
|
Stepholidine s a naturally occurring chemical compound found in the herb Stephania intermedia. Stepholidine is a dual D2 receptor antagonist and D1 receptor agonist, and has shown antipsychotic activity in animal studies. |
|
| DC10090 |
4-P-PDOT
Featured
|
4-P-PDOT is a slelctive MT2 melatonin receptor antagonist 300 fold selective for MT2 (MEL-1B-R) vs MT1 (MEL-1A-R) melatonin receptor subtype. |
|
| DC10689 |
4P-PDOT
Featured
|
4P-PDOT, also known as 4-phenyl-2- propionamidotetralin, is a MT2-receptor-specific antagonist. MT2 melatonin receptor may be a novel target for analgesic drug development. |
|
| DC10877 |
5,3-AB-CHMFUPPYCA
Featured
|
5,3-AB-CHMFUPPYCA is an analytical reference standard that is structurally classified as a synthetic cannabinoid. |
|
| DC7494 |
SB-242084 HCl
Featured
|
5-HT2C receptor antagonist that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2Breceptors respectively. Also displays selectivity over a range of other 5-HT, dopamine and adrenergic receptors. Brain penetrant; exerts anxiolytic-like activity. |
|
| DC7925 |
GTPL-5846 (6-OAU)
Featured
|
6-OAU(GTPL5846; 6-n-octylaminouracil) is a surrogate agonist of GPR84; activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105 nM in the PI assay. |
|
| DC10537 |
8-OH-DPAT
Featured
|
8-OH-DPAT is a research chemical of the aminotetralin chemical class and has been widely used to study the function of the 5-HT1A receptor. |
|
| DC7289 |
Imiloxan |
A moderately potent, but highly selective α2-adrenoceptor antagonist, the only reported selective antagonist at the α2B-adrenoceptor not having potent α1-adrenoceptor antagonist activity. |
|
| DCAPI1496 |
Ambrisentan
Featured
|
A nonpeptide endothelin ETA receptor antagonist. Antihypertensive. |
|
| DC11523 |
Landipirdine |
A novel 5-HT receptor antagonist for the treatment of Parkinson's disease.. |
|
| DC11994 |
ZQ-16 |
A novel potent and selective agonist of GPR84 that induces calcium response with EC50 of 0.213 uM. |
|
| DC11982 |
CX815 |
A novel potent, selective CXCR2 inhibitor with IC50 of 0.4 nM. |
|
| DC11981 |
CX4152 |
A novel potent, selective CXCR2 inhibitor with IC50 of 7.6 nM. |
|
| DC11605 |
ONO-0300302 |
A novel potent, slow tight binding LPA1 receptor antagonist with IC50 of 86 nM, Kd of 0.34 nM. |
|
| DC11974 |
L 741742 hydrochloride |
A potent and highly selective D4 dopamine receptor antagonist with Ki of 3.5 nM, >200-fold selectivity over D2 and D3 receptors. |
|
| DC11743 |
BMS-681 |
A potent and orally bioavailable dual antagonist of CCR2 and CCR5 with binding IC50 of 0.7 nM and 2.4 nM, respectively. |
|
| DC11705 |
GPR30 inhibitor G1
Featured
|
A potent and selective GPER/GPR30 agonist with Ki of 11 nM, EC50 of 2 nM. |
|
| DC11699 |
VUF11403 |
A potent CXCR7 (ACKR3) agonist.. |
|
| DC11976 |
SX-576 |
A potent, equipotent CXCR1 and CXCR2 antagonist with IC50 of 31 nM and 21 nM, respectively. |
|
| DC11903 |
NBUMP |
A potent, highly selective 5-HT1A receptor partial agonist with Ki of 0.1 nM, displays 460- and 260-fold selectivity for 5-HT1A over the α1-adrenergic and D2 receptors, respectively.. |
|
| DC11609 |
VU6010608 |
A potent, highly selective, CNS penetrant mGlu7 negative allosteric modulator with IC50 of 0.76 uM. |
|
| DC11758 |
PB 28 dihydrochloride
Featured
|
A potent, mixed sigma2 agonist and sigma1 antagonist with Ki of 0.28 and 13.0 nM, respectively. |
|
