Home > Inhibitors & Agonists > Antibiotics and Antivirals > Bacterial
Cat. No. Product name CAS No.
DC11768 TAM-16

A benzofuran class inhibitor of M. tuberculosis Pks13 (Polyketide Synthase 13).

2030241-59-7
DC11534 Sudoterb Featured

A novel anti-TB agent that has an MIC range of 0.06-0.5 ug/mL..

676266-31-2
DC11535 Sudoterb dihydrchloride

A novel anti-TB agent that has an MIC range of 0.06-0.5 ug/mL..

1044503-04-9
DC10513 AFN-1252(Debio 1452) Featured

AFN-1252(Debio 1452) is a potent inhibitor of enoyl-acyl carrier protein reductase (FabI), inhibited all clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis at concentrations of ≤0.12 μg/ml.

620175-39-5
DC9827 AN3365(Epetraborole) Featured

AN3365 is a first-in-class antibiotic that demonstrates potent activity across a wide spectrum of Gram-negative bacteria, including those resistant to many other antibiotics.

1234563-16-6
DC10552 AU1235 Featured

AU1235 is an adamantyl urea inhibitor of Mycobacterium tuberculosis.

1338780-86-1
DCAPI1362 Azithromycin (Zithromax)

Azithromycin (Zithromax)

83905-01-5
DC8809 Bedaquiline fumarate Featured

Bedaquiline fumarate(TMC207; R207910) is an anti-tuberculosis drug which selectively inhibit the mycobacterial energy metabolism i.e. ATP synthesis and found to be effective against all states of Mycobacterium tuberculosis.

845533-86-0
DC4143 Besifloxacin HCl Featured

Besifloxacin HCl is a fourth-generation fluoroquinolone antibiotic.

405165-61-9
DC10393 Bicyclomycin benzoate

Bicyclomycin benzoate is an antibiotic exhibiting activity against a broad spectrum of Gram-negative bacteria and against the Gram-positive bacterium.

37134-40-0
DC9853 BM212 Featured

BM-212 is a potent antimycobacterial agent and MmpL3 inhibitor.

146204-42-4
DCAPI1024 Cefditoren pivoxil

Cefditoren pivoxil

117467-28-4
DC8937 Clarithromycin

Clarithromycin is a macrolide antibiotic and a CYP3A4 inhibitor.

81103-11-9
DC11061 ClpP inhibitor M21

ClpP inhibitor M21 is a noncompetitive inhibitor of ClpP with IC50 of 41.42 uM, inhibits ClpP cleavage of SUc-LY-AMC substrate in a peptidase assay.

1151944-58-9
DCAPI1493 Dalbavacin Featured

Dalbavancin, a semisynthetic lipoglycopeptide being developed for the treatment of skin and skin structure infections (SSSIs), has a half-life of 5 to 7 days in humans and offers promise for a convenient weekly dosing regimen.

171500-79-1
DC7764 Delamanid (OPC-67683) Featured

Delamanid (OPC-67683) is an experimental drug for the treatment of multi-drug-resistant tuberculosis.

681492-22-8
DC10612 Delpazolid (LCB01-0371) Featured

Delpazolid (LCB01-0371) is a new oxazolidinone with cyclic amidrazone.

1219707-39-7
DC9949 DprE1-IN-2 Featured

DprE1-IN-2 is a potent DprE1 inhibitor.

1615713-87-5
DC8440 Erythromycin Cyclocarbonate Featured

Erythromycin Cyclocarbonate, derivative of Erythromycin, inhibits protein synthesis of bacteria by binding to the 50S ribosome.

55224-05-0
DC9350 Faropenem daloxate

Faropenem daloxate is the first oral penem in a new class of beta-lactam antibiotics.

141702-36-5
DC1057 Fidaxomicin (Dificid) Featured

Fidaxomicin, is an antibiotic that belongs to the class of macrocylic antibiotics.

873857-62-6
DC8847 Finafloxacin (BAY35-3377) Featured

Finafloxacin is a fluoroquinolone antimicrobial agent that exhibits optimum efficacy in slightly acidic environments.

209342-40-5
DC8047 VRT-1353385

For the detailed information of VRT-1353385, the solubility of VRT-1353385 in water, the solubility of VRT-1353385 in DMSO, the solubility of VRT-1353385 in PBS buffer, the animal experiment (test) of VRT-1353385, the cell expriment (test) of VRT-1353385, the in vivo, in vitro and clinical trial test of VRT-1353385, the EC50, IC50,and affinity,of VRT-1353385, For the detailed information of VRT-1353385, the solubility of VRT-1353385 in water, the solubility of VRT-1353385 in DMSO, the solubility of VRT-1353385 in PBS buffer, the animal experiment (test) of VRT-1353385, the cell expriment (test) of VRT-1353385, the in vivo, in vitro and clinical trial test of VRT-1353385, the EC50, IC50,and affinity,of VRT-1353385, Please contact DC Chemicals..

1616113-45-1
DC10307 Framycetin

Framycetin (Fradiomycin B; Neomycin B) is an aminoglycoside antibiotic. It inhibits hammerhead ribozyme with a Ki of 13.5 μM.

119-04-0
DC8929 Garenoxacin

Garenoxacin is a quinolone antibiotic for the treatment of Gram-positive and Gram-negative bacterial infections.

194804-75-6
DC8893 Garenoxacin Mesylate hydrate

Garenoxacin mesylate hydrate is a novel oral des-fluoro(6) quinolone with potent antimicrobial activity, against common respiratory pathogens, including resistant strains.

223652-90-2
DC10161 Gepotidacin Featured

Gepotidacin (GSK2140944) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor.

1075236-89-3
DC10567 KKL-10 Featured

KKL-10 is a small-molecule ribosome rescue inhibitor with broad-spectrum antimicrobial activity against bacteria.

952849-76-2
DC8775 LED209

LED209 is a potent QseC inhibitor that blocks both norepinephrine- and epinephrine-triggered QseC-dependent virulence gene expression at 5 pM in vitro.

245342-14-7
DC8928 Minocycline hydrochloride Featured

Minocycline is a tetracycline antibiotic with neuroprotective, antiapoptotic, anti-inflammatory and antimicrobial effects.

13614-98-7
DC4226 Moxifloxacin hydrochloride Featured

Moxifloxacin(Avelox, Avalox) is a fourth generation synthetic fluoroquinolone antibacterial agent.

186826-86-8
DC11273 Murepavadin (POL7080) Featured

Murepavadin is a novel class of highly specific outer membrane protein targeting antibiotic to treat resistant Pseudomonas infections.

944252-63-5
DCAPI1293 Nanchangmycin

Nanchangmycin (dianemycin) is a polyether antibiotic with similar structure to dianemycin and is very active against a broad spectrum of harmful nematodes and insects but not for for mammals and plants.

65101-87-3
DC11016 NOSO-502

NOSO-502 (NOSO502) is a novel inhibitor of bacterial translation, has MIC values of 0.5-4 ug/ml against standard Enterobacteriaceae strains and carbapenem-resistant Enterobacteriaceae (CRE) isolates that produce KPC, AmpC, or OXA enzymes and metallo-β-lactamases.

1894081-09-4
DC7625 PA-824(Pretomanid) Featured

PA-824 is an anti-tuberculosis drug for tuberculosis with MIC less than 2.8 μM.Phase 2.

187235-37-6
DC9723 PBTZ169 Featured

PBTZ169 is a decaprenyl-phosphoribose-epimerase (DprE1) inhibitor.

1377239-83-2
DC10441 Relebactam Featured

Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases [ESBLs] and KPC) and class C (AmpC) enzymes.

1174018-99-5
DC4148 Retapamulin

Retapamulin is a topical antibiotic, which binds to both E. coli and S. aureus ribosomes with similar potencies with Kd of 3 nM.

224452-66-8
DCAPI1325 Rifabutin (Mycobutin)

Rifabutin (Mycobutin)

72559-06-9
DC8032 Solithromycin Featured

Solithromycin is a novel ketolide antibiotic.

760981-83-7
DC10733 Sutezolid (PNU-100480) Featured

Sutezolid (PNU-100480) is an oxazolidinone antimicrobial being developed for the treatment of tuberculosis.

168828-58-8
DC7940 TBA-354

TBA-354 is a potent anti-tuberculosis compound; maintains activity against Mycobacterium tuberculosis H37Rv isogenic monoresistant strains and clinical drug-sensitive and drug-resistant isolates.

1257426-19-9
DC8336 Tizoxanide Featured

Tizoxanide is a potent inhibitor of hepatitis B virus and hepatitis C virus.

173903-47-4
DC10265 Tubercidin Featured

Tubercidin, an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhibits antifungal and antiviral activities.

69-33-0
DC10286 Vaborbactam Featured

Vaborbactam is a cyclic boronic acid pharmacophore β-lactamase inhibitor.

1360457-46-0
DC8115 Vancomycin hydrochloride Featured

Vancomycin hydrochloride in stock,price: 500 USD/100mg. 0

1404-93-9
DC10497 VXc-486 Featured

VXc-486 is active against drug-resistant isolates, has bactericidal activity, and kills intracellular and dormant M. tuberculosis bacteria in a low-oxygen environment.

1384984-18-2
DC7532 Walrycin-B Featured

Walrycin B is a novel antibacterial compound specifically targeting the essential WalR response regulator.

878419-78-4
DC11277 Zoliflodacin(AZD0914) Featured

Zoliflodacin (ETX0914;AZD0914) is a novel spiropyrimidinetrione bacterial DNA gyrase/topoisomerase inhibitor.

1620458-09-4
DC11102 Taniborbactam

1613267-49-4
DC10109 Q203 Featured

Q203 is a promising new clinical candidate for the treatment of tuberculosis.

1334719-95-7
DC28080 Ro 20-0657/000 Featured

Ro 20-0657/000 is a metabolite of Trimethoprim. Trimethoprim is a dihydrofolate reductase inhibitor, used as an antibacterial agent in human and veterinary medicine.

29606-06-2
DC28108 Flurofamide

Flurofamide is a potent bacterial urease inhibitor with potential clinical utility in the treatment of infection induced urinary stones.

70788-28-2
DC28191 Cefathiamidine

Cefathiamidine is a first-generation cephalosporin antibacterial agent and is used to treat infections caused by susceptible bacteria. Cefathiamidine exhibits a wide spectrum of antimicrobial activity against bacteria. Cefathiamidine is used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis.

33075-00-2
DC28215 A40926 Featured

A40926, the precursor of Dalbavancin, is a second-generation glycopeptide antibiotic. A40926 inhibits gram-positive bacteria, and is very active against Neisseria gonorrhoeae.

102961-72-8
DC28229 Cefodizime Featured

Cefodizime is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime has no renal toxic effect, good tolerance and immune regulation activity, and has the potential for severe infections of the respiratory and urinary tracts.

69739-16-8
DC28258 BM635 hydrochloride

BM635 hydrochloride is a MmpL3 inhibitor with outstanding anti-mycobacterial activity. BM635 hydrochloride has an MIC50 of 0.08 μM against M.tuberculosis H37Rv. BM635 hydrochloride doubles the in vivo exposure with respect to the free base BM635.

DC28259 BM635 mesylate

BM635 mesylate is a MmpL3 inhibitor with outstanding anti-mycobacterial activity. BM635 mesylate has a MIC50 of 0.6 μM against M. tuberculosis  H37Rv. BM635 mesylate significantly improves the bioavailability compared to free-base BM635.

DC28282 (3R,4R)-A2-32-01

(3R,4R)-A2-32-01 (compound 2), an anti-virulence drug, is a specific caseinolytic protein proteases (ClpP) inhibitor with an EC50 of 4.5 μM, and shows a tolerable cytotoxicity.

1359752-95-6
DC28403 Psicofuranine

Psicofuramine a nucleoside antibiotic and has the inhibition of xanthosine 5'-phosphate aminase. Psicofuranine also specifically inhibits GMP synthase, and interrupts parasite growth. Psicofuranine exhibits a dose-dependent inhibition of P. falciparum growth.

1874-54-0
DC28542 Ramoplanin

Ramoplanin is a broad-spectrum lipoglycodepsipeptide antibiotic derived from the Actinoplanes spp with with activity against gram-positive bacteria.

76168-82-6
DC28605 Benzothiohydrazide

Benzothiohydrazide is an analogue of anti–tubercular agent Isoniazid. Benzothiohydrazide exhibits anti–tubercular activity, with MICs of 132 μM and 264 μM for M. tuberculosis wild type (H37Rv) and clinical mutant strains (IC1 and IC2).

20605-40-7
DC28625 Sapienic acid

Sapienic acid is a fatty acid commonly found on the skin and in mucosa. Sapienic acid has variable antimicrobial activities against Gram-positive and Gram-negative bacteria found on the skin and in the oral cavity. Sapienic acid is active against Streptococcus sanguinis, Streptococcus mitis and Fusobacterium nucleatum with MBC values of 31.3 μg/mL, 375.0 μg/mL and 93.8 μg/mL, respectively.

17004-51-2
DC28626 Sapienic acid sodium

Sapienic acid sodium is a fatty acid commonly found on the skin and in mucosa. Sapienic acid sodium has variable antimicrobial activities against Gram-positive and Gram-negative bacteria found on the skin and in the oral cavity. Sapienic acid sodium is active against Streptococcus sanguinis, Streptococcus mitis and Fusobacterium nucleatum with MBC values of 31.3 μg/mL, 375.0 μg/mL and 93.8 μg/mL, respectively.

217477-25-3
DC28678 MAC-545496 Featured

MAC-545496 is a nanomolar inhibitor of glycopeptide-resistance-associated protein R (GraR). MAC-545496 displays strong binding affinity to the full-length GraR protein (Kd ≤ 0.1 nM). MAC-545496 is an antivirulence agent that reverses β-lactam resistance in Methicillin-resistant strains (MRSA).

838810-96-1
DC28735 PK150 Featured

PK150, an analogue of Sorafenib, shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations. PK150 inhibits Gram-positive Methicillin-sensitive S. aureus (MSSA), Methicillin-resistant S. aureus

2165324-62-7
DC28764 Glyceryl monocaprate

Glyceryl monocaprate (Monolaurin) is a 1-monoglyceride of capric acid against gram-positive bacterial infections. Glyceryl monocaprate (Monolaurin) has inhibitory effect on Herpes Simplex Virus (HSV) and offers an effective treatment for herpes labialiss.

26402-22-2
DC28779 Cefcapene pivoxil hydrochloride

Cefcapene pivoxil hydrochloride, an antibiotic, is an orally active and potent 3rd-generation cephalosporin with a wide spectrum of anti-bacterial activity.Cefcapene pivoxil hydrochloride has the potential for the palmoplantar pustulosis (PPP) treatment.

147816-23-7
DC28904 pVXc-​486

pVXc-486 is an orally active and potent phosphate prodrug of VXc-486. pVXc-486 has potent bactericidal activities in vivo.

1384984-20-6
DC28906 BSH-IN-1

BSH-IN-1 is a potent and covalent inhibitor of gut bacterial recombinant bile salt hydrolases (BSHs) with IC50s of 108 nM and 427 nM for B. longum BSH (Gram positive) and B. theta BSH (Gram negative), respectively.

DC28931 Gut restricted-7

Gut restricted-7 (GR-7) is a potent, covalent and orally active pan-bile salt hydrolase (BSH) inhibitor. Gut restricted-7 decreases gut bacterial BSHs and decreases deconjugated bile acid levels in feces of mice.

DC28952 LtaS-IN-1

LtaS-IN-1 (compound 1771) is a potent small-molecule inhibitor of Lipoteichoic acid (LTA) synthesis in multidrug-resistant (MDR) E. faecium and by altering the cell wall morphology. LtaS-IN-1 alone inhibits Enterococcus.spp 28 strains with varying MIC values ranging from 0.5 μg/mL to 64 μg/mL. LtaS-IN-1 combination with antibiotics abolishs multidrug-resistant E. faecium growth almost completely.

877950-01-1
DC29004 Sulfaclozine sodium

Sulfaclozine sodium (Sulfachloropyrazine sodium) is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine sodium is commonly used for the treatment of various poultry diseases (particularly, collibacteriosis, fowl cholera and coccidiosis).

23307-72-4
DC29037 Rosoxacin

Rosoxacin (Acrosoxacin) is a potent and orally active quinolone antibiotic. Rosoxacin (Acrosoxacin) has antibacterial activities against a broad spectrum of Gram negative bacteria including Neisseria gonorrhoeae (MIC90=0.03mg/ml). Rosoxacin has the potential for urinary tract infections treatment.

40034-42-2
DC29038 Clavulanate lithium

Clavulanate lithium is a potent β-lactamase inhibitor and acts as an antibiotic.

61177-44-4
DC29042 Sulfamethoxazole sodium

Sulfamethoxazole sodium (Ro 4-2130 sodium) is a sulfonamide bacteriostatic antibiotic. Sulfamethoxazole sodium is used to treat various urinary tract pathogens and in combination with Trimethoprim is considered the gold standard in the treatment of urinary tract infections (UTIs).

4563-84-2
DC29047 Enrofloxacin monohydrochloride

Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) is an effective antibiotic with an MIC90 of 0.312 μg/mL for Mycoplasma bovis.

93106-59-3
DC29073 Tiamulin

Tiamulin (Thiamutilin) is a diterpenic veterinary drug widely used in swine for the control of infectious diseases, including swine dysentery and enzootic pneumonia.

55297-95-5
DC29093 Magainin 1 TFA

Magainin 1 TFA is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis. Magainin 1 TFA exhibits antibiotic activity against numerous Gram-negative and Gram-positive bacteria.

DC29094 PGLa TFA

PGLa TFA, a 21-residue peptide, is an antimicrobial peptide. PGLa TFA is a member of the magainin family of antibiotic peptides found in frog skin and its secretions.

DC29123 SPR741 TFA

SPR741 TFA (NAB741 TFA) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 TFA increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infections. SPR741 TFA inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 TFA.

DC29124 SPR741 acetate

SPR741 acetate (NAB741 acetate) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 acetate increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infections. SPR741 acetate inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 acetate.

DC29152 Globomycin

Globomycin is a lipopeptide antibiotic and a signal peptidase II (LspA) inhibitor. Globomycin inhibits processing of the prolipoprotein by binding irreversibly to the peptidase. Globomycin has toxic for the mollicute Spiroplasma melliferum with a MIC in the range 6.25-12.5 μM.

67076-74-8
DC31051 GSK-1322322

A novel antibacterial agent that targets bacterial peptide deformylase.

1152107-25-9
DC31052 GSK-729

A potent, small molecule inhibitor of Mycobacterium tuberculosis enoyl-coenzyme A (CoA) hydratase EchA6 with IC50 of 1.8 uM, but not the MmpL3.

1260243-45-5
DC31056 GSK 951A

A small molecule with bactericidal efficacy against Mycobacterium tuberculosis with H37Rv MIC of 0.16 uM.

1403602-33-4
DC40057 Dicresulene diammonium

Dicresulene diammonium is an impurity of Policresulen, an organic acid with hemostatic, antimicrobial and antiviral activities.

DC40067 Cefteram pivoxil

Cefteram pivoxil (Ro 19-5248), an orally active cephalosporin antibiotic, is used for bacterial infections.

82547-81-7
DC40069 Polymyxin B nonapeptide TFA

Polymyxin B nonapeptide TFA is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. Polymyxin B nonapeptide TFA is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing their outer membranes.

2220175-42-6
DC40091 Potassium guaiacolsulfonate hemihydrate

Potassium guaiacolsulfonate hemihydrate is an orally active expectorant used for acute respiratory tract infections. Potassium guaiacolsulfonate hemihydrate helps loosen mucus and used for a cough caused by the common cold, infections or allergies in combination with other drugs.

78247-49-1
DC40116 Demecycline

Demecycline, a tetracycline antibiotic, is the C6-demethylated derivative of Tetracycline against bacterial infections including pneumonia and other respiratory tract infections.

987-02-0
DC40138 Chrysomycin B

Chrysomycin B is an antibiotic isolated from a strain of Streptomyces. Chrysomycin B causes DNA damage in the human lung adenocarcinoma A549 cell line and inhibits topoisomerase II. Chrysomycin B suppresses the growth of transplantable tumors in mice.

83852-56-6
DC40217 Metronidazole acetic acid Featured

Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa.

1010-93-1
DC40219 VU0420373

VU0420373 is a potent heme sensor system (HssRS) activator with an EC50 of 10.7 μM and a pEC50 of 4.97. VU0420373 induces heme biosynthesis, and is toxic to fermenting S. aureus.

38376-29-3
DC40220 Bisdionin C

Bisdionin C is a potent GH18 chitinases inhibitor, with an IC50 of 0.2 μM for A. fumigatus ChiB1 (AfChiB1). Bisdionin C inhibits HCHT (human macrophage chitotriosidase) and acidic mammalian chitinase (AMCase) with IC50s of 8.3 and 3.4 μM, respectively.

74857-22-0
DC40243 N-(Hydroxymethyl)nicotinamide

N-(Hydroxymethyl)nicotinamide is an antimicrobic agent.

3569-99-1
DC40253 12-Oxo phytodienoic acid

12-Oxo phytodienoic acid is a biologically active, immediate precursor of 7-epi jasmonic acid. 12-Oxo phytodienoic acid appears to play an independent role in mediating resistance to pathogens and pests.

85551-10-6
DC40267 Alafosfalin

Alafosfalin is an inhibitor of cell wall biosynthesis. Alafosfalin is a phosphonodipeptide with antibacterial properties.

60668-24-8
DC40271 N-Acetyltyramine

N-Acetyltyramine is a quorum-sensing inhibitor (QSI) compound produced by V. alginolyticus M3-10. N-Acetyltyramine is capable of inhibiting the QS of C. violaceum ATCC 12472. N-acetyltyramine reverses resistance in Doxorubicin-resistant leukemia P388 cells.

1202-66-0
DC40279 Difloxacin

Difloxacin is an antimicrobial agent.

98106-17-3
DC40280 Difloxacin D3 hydrochloride trihydrate

Difloxacin D3 hydrochloride trihydrate is a deuterium labeled Difloxacin. Difloxacin is an antimicrobial agent.

DC40327 N-Octanoyl-L-homoserine lactone

N-octanoyl-L-Homoserine lactone is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. N-octanoyl-L-Homoserine lactone can be used for the infection prevention and regulation of virulence in general and in cystic fibro.

147852-84-4
DC40342 Actinomycin X2

Actinomycin X2 (Actinomycin V), produced by many Streptomyces sp., shows strong inhibition of MRSA with a minimum inhibitory concentration (MIC) value of 0.25 μg/mL. Actinomycin X2 can be used for cancer and bacterial infection.

18865-48-0
DC40347 2-Mercaptopyridine N-oxide sodium

2-Mercaptopyridine N-oxide sodium has bactericidal effect and is against a standard strain of Mycobacterium tuberculosis H37Rv (ATCC 27294) with MIC90 of 7.20 μM. 2-Mercaptopyridine N-oxide sodium and its complex with iron, gallium, and bismuth have good anti-M. tuberculosis activity. 2-Mercaptopyridine N-oxide sodium has potential for the treatment of tuberculosis.

3811-73-2
DC40365 Tirandamycin A

Tirandamycin A, an antibiotic, is a bacterial RNA polymerase inhibitor. Tirandamycin A has antiamoebic and antibacterial properties.

34429-70-4
DC40382 Benzyldodecyldimethylammonium chloride dihydrate

Benzyldodecyldimethylammonium chloride dihydrate is a quaternary ammonium compound (QAC) and can be used as a biocide to target antibiotic-resistant bacteria, such as methicillin-resistant?Staphylococcus aureus?(MRSA), multidrug-resistant (MDR)?P. aeruginosa?et. al. Benzyldodecyldimethylammonium chloride dihydrate, an antimicrobial agent, bacteriostatic or bactericidal properties depending on the concentration.

147228-80-6
DC40386 Tylvalosin tartrate

Tylvalosin tartrate (Acetylisovaleryltylosin tartrate) is a macrolide antibiotic that can against Gram-positive bacteria.

63428-13-7
DC40389 2'-Hydroxy-2-methoxychalcone

2'-Hydroxy-2-methoxychalcone (compound 3b) is a synthetic chalcone, with antimicrobial activity.

42220-77-9
DC40391 Dehydroacetic acid sodium

Dehydroacetic acid sodium, a pyrone derivative acts as an antibacterial and antifungal agent. Dehydroacetic acid possess phytotoxic activity.

4418-26-2
DC40399 MRL-494 hydrochloride

MRL-494 hydrochloride, an antibacterial agent, is a inhibitor of β-barrel assembly machine A (BamA) impervious to efflux and the outer membrane permeability barrier. MRL-494 hydrochloride can inhibits Gram-positive (MIC of 12.5 μM for Staphylococcus aureus COL) and Gram-negative (MIC of 25 μM for E. coli JCM158) bacterias.

DC40400 SPR206 acetate

SPR206 acetate is a polymyxin analog with antibiotic activity against Gram-negative pathogens, including multidrug-resistant (MDR) variants. SPR206 acetate has an anti-bacterial infection effect by interacting with the bacterium’s outer membrane. The MIC values of SPR206 acetate against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301 are both 0.125 mg/L.

2408422-41-1
DC40418 Bafilomycin C1

Bafilomycin C1 is a macrolide antibiotic isolated from Streptomyces sp. Bafilomycin C1 is a potent, specific and reversible inhibitor of vacuolar-type H+-ATPases (V-ATPases). Bafilomycin C1 inhibits growth of gram-positive bacteria and fungi. Bafilomycin C1 induces cell apoptosis and can be used for the study of hepatocellular carcinoma (HCC).

88979-61-7
DC40486 Mequindox

Mequindox is an antimicrobial agent. Mequindox acts as an inhibitor of DNA synthesis. Mequindox induces genotoxicity and carcinogenicity in mice.

13297-17-1
DC40493 Cefpodoxime proxetil impurity B

Cefpodoxime proxetil impurity B is an impurity of Cefpodoxime proxetil. Cefpodoxime Proxetil is a first oral and broad spectrum antibiotic that belongs to the third generation of cephalosporin.

947692-14-0
DC40646 Senecivernine

Senecivernine, a pyrrolizidine alkaloid isolated from Senecio species, exhibits a weakly mutagenic activity.

72755-25-0
DC40647 Neoabietic acid

Neoabietic acid is an abietic-type acid isolated from the oleoresin and rosin of Pinus palustris. Neoabietic acid is highly susceptible to mineral acid. Neoabietic acid has antibacterial activity in vitro.

471-77-2
DC40714 N-Tetradecanoyl-L-homoserine lactone

N-Tetradecanoyl-L-homoserine lactone is a major chemical modulators of within and between cell communication and regulation. N-Tetradecanoyl-L-homoserine lactone can be used for the study of quorum sensing in vitro.

202284-87-5
DC40718 Pyrrolnitrin Featured

Pyrrolnitrin is an antibiotic isolated from Pseudomonas pyrrocinia. Pyrrolnitrin shows a broad spectrum of antibiotic activity against fungi, yeast and gram-positive bacteria.

1018-71-9
DC40857 N-Acetylmuramic acid-alkyne

N-Acetylmuramic acid-alkyne is a derivative of N-acetylmuramic acid (NAM) component of bacterial peptidoglycans. N-Acetylmuramic acid-alkyne incorporates into bacterial peptidoglycans during biosynthesis. N-Acetylmuramic acid-alkyne can be used for fluorescent labeling of peptidoglycans when 'click'-conjugated to a fluorescent dye.

2245794-65-2
DC40886 Oxazosulfyl

Oxazosulfyl is a potent agricultural fungicide. Oxazosulfyl can be used as an insecticide against major rice pests.

1616678-32-0
DC40924 N-Decanoyl-L-homoserine lactone

N-Decanoyl-L-homoserine lactone is a member of N-acyl-homoserine lactone family. N-Acylhomoserine lactones (AHL) regulate gene expression in Gram-negative bacteria, such as Echerichia and Salmonella, and are involved in quorum sensing, cell to cell communication among bacteria.

177315-87-6
DC40930 Ethylhydrocupreine

Ethylhydrocupreine (Optochin) is a quinine derivate with antimicrobial activity against S. pneumoniae. Ethylhydrocupreine also possesses antimalarial activity against Plasmodium falciparum, with an IC50 of 25.75 nM. Ethylhydrocupreine is a Gallus gallus taste 2 receptors (ggTas2r1, ggTas2r2 and ggTas2r7) agonist.

522-60-1
DC40931 Ethylhydrocupreine hydrochloride

Ethylhydrocupreine hydrochloride (Optochin hydrochloride) is a quinine derivate with antimicrobial activity against S. pneumoniae. Ethylhydrocupreine hydrochloride also possesses antimalarial activity against Plasmodium falciparum, with an IC50 of 25.75 nM. Ethylhydrocupreine hydrochloride is a Gallus gallus taste 2 receptors (ggTas2r1, ggTas2r2 and ggTas2r7) agonist.

3413-58-9
DC40940 Hydroxymetronidazole

Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle.

4812-40-2
DC40941 Triclosan-methyl

Triclosan-methyl is a transformation product of triclosan. Triclosan is a bactericide in personal care products such as toothpaste, shampoos, and soaps. Triclosan is also a stabilizing agent in a multitude of detergents and cosmetics.

4640-01-1
DC40962 Coenzyme FO

Coenzyme FO, a deazaflavin chromophore, acts as an important hydride acceptor/donor in the central methanogenic pathway.

37333-48-5
DC40999 Demethyl linezolid

Demethyl linezolid is a impurity of linezolid. Demethyl linezolid is a useful antimicrobial agent extracted from patent WO1995007271A1, example 9, effective against a number of human and veterinary pathogens.

168828-65-7
DC41073 Avibactam free acid

Avibactam free acid (NXL-104 free acid) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively.

1192500-31-4
DC41076 Spergualin trihydrochloride

Spergualin trihydrochloride is a natural product that first identified as an antibiotic from culture filtrates of Bacillus laterosporus BMG162-aF2.

80952-47-2
DC41131 Brilacidin tetrahydrochloride

Brilacidin tetrahydrochloride (PMX 30063 tetrahydrochloride) is an anti-infective antimicrobial with MIC90s of 1 and 8 μg/mL for Gram-positive bacteria Streptococcus pneumonia and Streptococcus viridans, and MIC90 of 8 and 4 μg/mL for Gram-negative bacteria Haemophilus influenza and Pseudomonas aeruginosa. Brilacidin tetrahydrochloride is a defensin mimetic antibiotic compound.

1224095-99-1
DC41132 Contezolid acefosamil

Contezolid acefosamil (MRX-4) is the orally active prodrug of the active antimicrobial metabolite Contezolid (MRX-I), an oxazolidinone which shows potent in vitro activity against various multidrug-resistant Gram-positive bacteria, including MRSA

1807497-11-5
DC41145 S.pombe lumazine synthase-IN-1

S.pombe lumazine synthase-IN-1 is an inhibitor of lumazine synthases with Ki values of 243 μM and 9.6 μM for Schizosaccharomyces pombe and Mycobacterium tuberculosis lumazine synthases, respectively.

331726-35-3
DC41155 Quinupristin mesylate

Quinupristin mesylate is a streptogramin antibiotic. Quinupristin mesylate blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits.

DC41156 Cilastatin sodium Featured

Cilastatin sodium (MK0791 sodium) is a reversible, competitive renal dehydropeptidase I inhibitor with an IC50 of 0.1 μM. Cilastatin sodium inhibits the bacterial metallob-lactamase enzyme CphA with an IC50 of 178 μM. Cilastatin sodium is an antibacterial adjunct.

81129-83-1
DC41157 Colistin methanesulfonate sodium salt

Colistin methanesulfonate sodium salt exhibits MIC values ranged from 4 to 16 mg/liter against susceptible strains (P. aeruginosa).

8068-28-8
DC41163 Tigecycline hydrate Featured

Tigecycline hydrate is a broad spectrum glycylcycline antibiotic. Tigecycline hydrate is bacteriostatic, that inhibits protein synthesis by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation. Tigecycline hydrate is active against resistant strains of Gram-positive and Gram-negative bacteria.

1229002-07-6
DC41164 Norfloxacin-d5

Norfloxacin-d5 is a deuterium labeled Norfloxacin. Norfloxacin is a fluoroquinolone antibiotic that inhibits the growth of Gram-positive and Gram-negative bacteria (MICs = 4 μg/mL and 1 μg/mL for S. aureus and P. aeruginosa, respectively). Norfloxacin also inhibits the growth S. pseudintermedius, S. aureus, E. coli, Pasturella, and S. canis isolates from dogs (mean MIC50s = 0.25 μg/mL, 1 μg/mL, 0.03 μg/mL, 1 μg/mL, and 1 μg/mL, respectively).

1015856-57-1
DC41166 Cefoperazone dihydrate

Cefoperazone dihydrate, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity.

113826-44-1
DC41167 Erythromycin A dihydrate

Erythromycin dihyrate dihydrate is a macrolide antibiotic produced by actinomycete?Streptomyces erythreus?with a broad spectrum of antimicrobial activity. Erythromycin dihyrate acts by binding to bacterial 50S ribosomal subunits and inhibits?RNA-dependent protein synthesis?by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid.

59319-72-1
DC41168 Chloramphenicol D5

Chloramphenicol D5 is the deuterium labeled Chloramphenicol. Chloramphenicol is a broad-spectrum antibiotic against bacterial infections.

202480-68-0
DC41173 Sulfadimethoxine D6

Sulfadimethoxine D6 is the deuterium labeled Sulfadimethoxine. Sulfadimethoxine is a sulfonamide antibiotic used to treat many infections.

73068-02-7
DC41176 Nalidixic acid sodium salt

Nalidixic acid sodium salt, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria.

3374-05-8
DC41214 Furaltadone

Furaltadone, a nitrofuran drug, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci .

139-91-3
DC41215 Furaltadone L-tartrate

Furaltadone L-tartrate (Altafur L-tartrate), a nitrofuran drug, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci .

14343-71-6
DC41217 Chlorhexidine acetate hydrate

Chlorhexidine acetate hydrate is an antibacterial used as an antiseptic and for other applications. Chlorhexidine acetate hydrate is used to clean the skin after an injury, before surgery, or before an injection. Chlorhexidine acetate hydrate is also used to clean the hands before a procedure.

206986-79-0
DC41218 Cefuroxime

Cefuroxime is an orally active second-generation cephalosporin antibiotic with increased stability to β-lactamase. Cefuroxime has a broad spectrum activity against Gram-positive and Gram-negative bacteria.

55268-75-2
DC41222 Cefixime trihydrate

Cefixime trihydrate (FR-17027 trihydrate) is an antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections.

125110-14-7
DC41223 Halazone

Halazone is an atypical antimicrobial sulfonamide derivative and a carbonic anhydrase II inhibitor with a Kd value of 1.45 μM. Halazone protects sodium channels from inactivation. Halazone is widely used for disinfection of drinking water.

80-13-7
DC41226 Silver sulfadiazine

Silver sulfadiazine (AgSD), a sulfonamide antibiotic, effects a dual inhibitory action on bacterial growth by its sulfa moiety (SD-SDZ) that prevents bacterial folate absorption and subsequent DNA synthesis. The silver that is released from Silver sulfadiazine binds and disrupts the DNA structure, precluding bacterial DNA replication.

22199-08-2
DC41235 Phenoxyethanol Featured

Phenoxyethanol has a broad spectrum of antimicrobial activity against various gram-negative and gram-positive bacteria. Phenoxyethanol is an uncouple agent in oxidative phosphorylation from respiration and competitively inhibits malate dehydrogenase. Phenoxyethanol is used as a preservative in cosmetic, vaccine, and textile, et al.

122-99-6
DC41271 Resorufin pentyl ether

Resorufin pentyl ether (Pentoxyresorufin; 7-Pentoxyphenoxazone) is a Resazurin analogue. Resorufin pentyl ether acts as a substrate to distinguish between different induced cytochromes P-450. Resorufin pentyl ether maintains bactericidal activity against N. gonorrhoeae in vitro.

87687-03-4
DC41306 Sideroxylin

Sideroxylin is a C-methylated flavone isolated from Callistemon lanceolatus and exerts antimicrobial activity against Staphylococcus aureus. Sideroxylin inhibits ovarian cancer cell proliferation and induces apoptosis, causing DNA fragmentation, depolarization of the mitochondrial membrane, the generation of reactive oxygen species (ROS).

3122-87-0
DC41307 Sinapaldehyde

Sinapaldehyde, isolated from the stems of Rhodamnia dumetorum, exhibits moderate antibacterial against Methicillin resistant S. aureus (MRSA) and E. coli with MIC values of 128 and 128 μg/mL.

4206-58-0
DC41309 2,5-Dihydroxybenzaldehyde

2,5-Dihydroxybenzaldehyde (Gentisaldehyde) is a naturally occurring antimicrobial that inhibits the growth of Mycobacterium avium subsp. paratuberculosis. 2,5-Dihydroxybenzaldehyde is active against S. aureus strains with a MIC50 of 500 mg/L.

1194-98-5
DC41320 Isobavachromene

Isobavachromene is an antibacterial agent.

52801-22-6
DC41347 Ombuoside

Ombuoside is a glycoside ombuoside isolated from Gynostemma pentaphyllum.Ombuoside has antimicrobial activity against several strains of gram-positive and gram-negative bacteria and the yeast Candida albicans. Ombuoside has antioxidant effects by scavenging free radicals and ROS.

20188-85-6
DC41349 Neorauflavene

Neorauflavene is a phenolic neorautanenia isoflavanoid isolated from Neorautanenia edulis. Neorauflavene shows antibacterial activities against E. faecalis, S. suis, S. agalactiae, P. aeruginosa, B. subtilis, and R. anatipestifer.

53734-75-1
DC41350 Mucrolidin

Mucrolidin is an eudesmane-type sesquiterpenoid isolated from aerial parts of homalomena occulta. Mucrolidin exhibits weak antibacterial activities when it compares to Rifampicin.

227471-20-7
DC41365 Ermanin

Ermanin is a flavonoid isolated from Tanacetum microphyllum. Ermanin potently inhibits iNOS, COX-2 activities, and inhibits platelet aggregation. Ermanin has anti-inflammatory, anti-tuberculous and anti-viral/bacterial properties.

20869-95-8
DC41368 Ganoderol A

Ganoderol A is a terpenoid extracted from Ganoderma lucidum with antimicrobial activities. Ganoderol A inhibits cholesterol synthesis pathway and has significant anti-inflammatory activity and protection against ultraviolet A (UVA) damage.

104700-97-2
DC41370 Isoastilbin

Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg/mL, and also inhibits tyrosinase activity. Isoastilbin shows neuroprotective, antioxidation, antimicrobial and anti-apoptotic properties and has the potential for Alzheimer’s disease research.

54081-48-0
DC41380 Ginsenoside Rg4

Ginsenoside Rg4 is a major protopanaxatriol type ginsenoside isolated from the leaves of Panax ginseng C. A. Meyer. The protopanaxatriol type ginsenosides (such as Ginsenoside Rg4) exhibits various biological activities including anti-septic, anti-diabetic, wound healing, immune-stimulatory, and anti-antioxidant activity.

126223-28-7
DC41383 Skullcapflavone II

Skullcapflavone II, a flavonoid derived from Scutellaria baicalensis, has anti-inflammatory, anti-microbial activities. Skullcapflavone II regulates osteoclast differentiation, survival, and function. Skullcapflavone II exerts potent antimicrobial activity against M. aurum and M. bovis BCG.

55084-08-7
DC41387 Calcimycin hemimagnesium

Calcimycin (A-23187) hemimagnesium is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin hemimagnesium induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin hemimagnesium inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin hemimagnesium also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin hemimagnesium induces apoptosis.

72124-77-7
DC41395 3-O-Methylellagic acid

3-O-Methylellagic acid is a nature product isolated from Myrciaria cauliflora, with anti-inflammatory activity. 3-O-Methylellagic acid shows an inhibitory effect on glucose transport assay. 3-O-Methylellagic acid has antibacterial activity, with a MIC of 32 μg/mL for Staph. Aureus ATCC 25923.

51768-38-8
DC41396 Levopimaric acid

Levopimaric acid is a type of diterpene resin acid produced by plants. Levopimaric acid induces cancer cell apoptosis and has anticancer, antioxidant, antibacterial and cardiovascular activities.

79-54-9
DC41397 DIMBOA Featured

DIMBOA, an antibiotic, is a benzoxazinoid, part of the chemical defense system of graminaceous plants such as maize, wheat, and rye. DIMBOA possess growth inhibitory properties against many strains of studied bacteria and fungi, such as Staphylococcus aureus, Escherichia coli as well as against Saccharomyces cerevisiae. DIMBOA exhibits a potent free-radical scavenging activity and a weaker iron (III) ions reducing activity. Antioxidant activity.

15893-52-4
DC41404 Neamine

Neamine is a non-toxic derivative derivative of Neomycin and is a broad-spectrum aminoglycoside antibiotic. Neamine is an anti-angiogenesis agent targeting angiogenin. Neamine has potent antibacterial, antitumor and neuroprotective activities.

3947-65-7
DC41414 Isopsoralenoside

Isopsoralenoside is a benzofuran glycoside from Psoralea corylifolia. Isopsoralenoside can be quickly metabolized to Psoralen in digestive tract contents. Isopsoralenoside show estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity.

905954-18-9
DC41415 Norchelerythrine

Norchelerythrine is an alkaloid isolated from the roots of Zanthoxylum capense with antibacterial activity against gram-positive and gram-negative bacteria. Norchelerythrine exhibits inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Enterococcus faecalis and Escherichia coli with MIC values >50 μg/mL.

6900-99-8
DC41421 Pinocembrin chalcone

Pinocembrin chalcone (2',4',6'-Trihydroxychalcone) is an antibacterial compound from Helichrysum Trilineatum. Pinocembrin chalcone can prevent gastric ulcers in rats.

4197-97-1
DC41434 Kipukasin D

Kipukasin D is an natural nucleoside derived from Aspergillus versicolor with antibacterial activity.

948574-00-3
DC41435 Acetylalkannin

Acetylalkannin (Alkannin acetate) is an isohexenylnaphthazarin pigment isolated from Arnebia euchroma with antimicrobial and cytotoxic activities.

34232-27-4
DC41443 5-Desmethylsinensetin

5-desmethylsinensetin, isolated from Stevia satureiifolia var. satureiifolia, possesses antiprotozoal activity. 5-desmethylsinensetin shows IC50 values of 0.4 μg/mL on T. cruzi epimastigotes and 75.1 μg/mL on trypomastigotes, respectively.

21763-80-4
DC41448 Comanthoside B

Comanthoside B is a flavonoid glycoside isolated from the aerial portions of Ruellia tuberosa L. Comanthoside B has anti-inflammatory and antiseptic activities.

70938-60-2
DC41453 Terminolic acid

Terminolic acid is a pentacyclic triterpenoid glucoside isolated from Combretum racemosum. Terminolic acid can inhibit the pro-inflammatory cytokines by binding to receptor active site of IL-1β and IL-6, and enhance anti-inflammatory cytokines by binding to IL-4 receptor binding sites. Terminolic acid also exhibits moderate antibacterial activity.

564-13-6
DC41488 Lehmannine

Lehmannine is a quinolizidine bioalkaloid isolated from S. alopecuroides L, has antibacterial, anti-inflammatory and anti-tumor activities.

58480-54-9
DC41527 Dermaseptin TFA

Dermaseptin TFA, a peptide isolated from frog skin, exhibits potent antimicrobial activity against?bacteria,?fungi, and?protozoa?at micromolar concentration.

DC41548 Lauryl-LF 11

Lauryl-LF 11, N-terminally acylated analogue of LF11, is a peptide with antibacterial activity.

832729-14-3
DC41549 Lauryl-LF 11 TFA

Lauryl-LF 11 TFA, N-terminally acylated analogue of LF11, is a peptide with antibacterial activity.

DC41550 LF11

LF11 is a peptide with antibacterial activity.

832729-13-2
DC41551 LF11 TFA

LF11 TFA is a peptide with antibacterial activity.

DC41597 PBP10

PBP10 is a cell permeable and selective gelsolin-derived peptide inhibitor of formyl peptide receptor 2 (FPR2) over FPR1. PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects.

794466-43-6
DC41598 PBP10 TFA

PBP10 is a cell permeable and selective gelsolin-derived peptide inhibitor of formyl peptide receptor 2 (FPR2) over FPR1. PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects.

DC41838 Bactenecin TFA

Bactenecin TFA (Bactenecin, bovine TFA) is a potent 12-aa looped antimicrobial peptide isolated from bovine neutrophils. Bactenecin TFA inhibits the growth of bacteria and yeast, and kills the fungus Trichophyton rubrum. Bactenecin TFA increass membrane permeability, inhibits the growth and biofilm formation of B. pseudomallei.

DC41845 Temporin A

Temporin A is a short alpha-helical antimicrobial peptide isolated from the skin of the frog Rana temporaria. Temporin A is effective against a broad spectrum of Gram-positive bacteria. Temporin A interacts directly with the cell membrane of the microorganism and it is non-toxic to erythrocytes at concentrations that are antimicrobial. Temporin A also has antifungal activities (against yeast-like Candida albicans).

188713-69-1
DC41846 Cinnamycin

Cinnamycin is tetracyclic lantibiotic produced from S. cinnamoneus that contains four unusual amino acids: erythro-β-hydroxyaspartic acid, mesolanthionine, threo-β-methyllanthionine, and lysinoalanine.1 Cinnamycin has demonstrated antiviral activity against herpes simplex virus type 1 KOS strain infection in Vero cells via a cytopathic effect reduction assay. Cinnamycin recognizes the structure of phosphatidylethanolamine and forms an equimolar complex with the phospholipid on biological membranes. This peptide has been used as a probe for analyzing the transbilayer movement of phosphatidylethanolamine.

110655-58-8
DC41853 Lactoferrin (17-41) (acetate)

Lactoferrin 17-41 (Lactoferricin B) acetate, a peptide corresponding to residues 17-41 of bovine lactoferrin, has antimicrobial activity against a wide range of microorganisms, including Gram-positive and Gramnegative bacteria, viruses, protozoa, and fungi. Lactoferrin 17-41 acetate has antitumor activities.

DC41863 Colistin A

Colistin A is a major component of Colistin. Colistin is a polymyxin antibiotic and can be used to combat infections caused by problematic gram-negative bacteria.

7722-44-3
DC41864 Colistin A sulfate hydrate

Colistin A sulfate hydrate is a major component of Colistin. Colistin is a polymyxin antibiotic and can be used to combat infections caused by problematic gram-negative bacteria.

DC41889 Beta-defensin 103 isoform X1, pig

Beta-defensin 103 isoform X1, pig is an antimicrobial peptide found in different living organisms, involved in the first line of defense in their innate immune response against pathogens.

DC41890 Beta-defensin 103 isoform X1, pig TFA

Beta-defensin 103 isoform X1, pig TFA is an antimicrobial peptide found in different living organisms, involved in the first line of defense in their innate immune response against pathogens.

DC41891 Omiganan-FITC TFA

Omiganan-FITC TFA is a peptide-FITC complex composed of Omiganan and a FITC. Omiganan is a bactericidal and fungicidal cationic peptide being developed as a topical gel for prevention of catheter-associated infections.

DC41908 IDR-1

IDR-1 is an antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria. IDR-1 counters infection by selective modulation of innate immunity without obvious toxicities. IDR-1 has anti-inflammatory and anti-infective properties, enhances the levels of monocyte chemokines, and attenuates pro-inflammatory cytokine release.

940291-10-1
DC41912 Lactoferricin B (4-14), bovine TFA

Lactoferricin B (4-14), bovine (TFA), a peptide corresponding to residues 4-14 of bovine lactoferrin, has antimicrobial activity against a wide range of microorganisms.

DC41913 Gramicidin A

Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A induces degradation of hypoxia inducible factor 1 α (HIF-1α).

11029-61-1
DC41915 Gramicidin C

Gramicidin C is a naturally occuring polypeptide antibiotic isolated from B. brevis var. G.B.

9062-61-7
DC41916 Lysostaphin

Lysostaphin is an antistaphylococcal agent. Lysostaphin has activities of three enzymes namely, glycylglycine endopeptidase, endo-β-N-acetyl glucosamidase and N-acteyl muramyl-L-alanine amidase.

9011-93-2
DC41966 CSP1

CSP1 is a potent and selective ComD1 receptor agonist, with an IC50 of 10.3 nM. CSP1 is a major variants of competence-stimulating peptide (CSP), and it can regulate genetic transformation of S. pneumonia by modulating quorum sensing (QS). CSP1 can act as an antibacterial agent.

172889-49-5
DC41969 rCRAMP (rat)

rCRAMP (rat) is the rat cathelin-related antimicrobial peptide. rCRAMP (rat) contributes to the antibacterial activity in rat brain peptide/protein extracts. rCRAMP (rat) is a potential key player in the innate immune system of rat CNS.

376364-38-4
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