A benzofuran class inhibitor of M. tuberculosis Pks13 (Polyketide Synthase 13).

A novel anti-TB agent that has an MIC range of 0.06-0.5 ug/mL..

A novel anti-TB agent that has an MIC range of 0.06-0.5 ug/mL..

AFN-1252(Debio 1452) is a potent inhibitor of enoyl-acyl carrier protein reductase (FabI), inhibited all clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis at concentrations of ≤0.12 μg/ml.

AN3365 is a first-in-class antibiotic that demonstrates potent activity across a wide spectrum of Gram-negative bacteria, including those resistant to many other antibiotics.

AU1235 is an adamantyl urea inhibitor of Mycobacterium tuberculosis.

Azithromycin (Zithromax)

Bedaquiline fumarate(TMC207; R207910) is an anti-tuberculosis drug which selectively inhibit the mycobacterial energy metabolism i.e. ATP synthesis and found to be effective against all states of Mycobacterium tuberculosis.

Besifloxacin HCl is a fourth-generation fluoroquinolone antibiotic.

Bicyclomycin benzoate is an antibiotic exhibiting activity against a broad spectrum of Gram-negative bacteria and against the Gram-positive bacterium.

BM-212 is a potent antimycobacterial agent and MmpL3 inhibitor.

Cefditoren pivoxil

Clarithromycin is a macrolide antibiotic and a CYP3A4 inhibitor.

ClpP inhibitor M21 is a noncompetitive inhibitor of ClpP with IC50 of 41.42 uM, inhibits ClpP cleavage of SUc-LY-AMC substrate in a peptidase assay.

Dalbavancin, a semisynthetic lipoglycopeptide being developed for the treatment of skin and skin structure infections (SSSIs), has a half-life of 5 to 7 days in humans and offers promise for a convenient weekly dosing regimen.

Delamanid (OPC-67683) is an experimental drug for the treatment of multi-drug-resistant tuberculosis.

Delpazolid (LCB01-0371) is a new oxazolidinone with cyclic amidrazone.

DprE1-IN-2 is a potent DprE1 inhibitor.

Erythromycin Cyclocarbonate, derivative of Erythromycin, inhibits protein synthesis of bacteria by binding to the 50S ribosome.

Faropenem daloxate is the first oral penem in a new class of beta-lactam antibiotics.

Fidaxomicin, is an antibiotic that belongs to the class of macrocylic antibiotics.

Finafloxacin is a fluoroquinolone antimicrobial agent that exhibits optimum efficacy in slightly acidic environments.