Cat. No. | Product name | CAS No. |
DC72119 |
Deruxtecan analog 2
Deruxtecan analog 2 (example 9 P3) is a Deruxtecan analog. Deruxtecan analog 2 is a drug-linker conjugate composed of Camptothecin and a linker. Camptothecin (CPT) is a Topo I inhibitor with antineoplastic activity against colorectal, breast, lung and ovarian cancers. Deruxtecan analog 2 can be used for the preparation anti-FGFR2 ADC. |
1599440-10-4 |
DC72257 |
TAM558
TAM558 is a payload molecule used for the synthesis of OMTX705. OMTX705 is a humanized anti-fibroblast-activating protein (FAP) antibody conjugated to the cytolysin TAM470, with antitumor activity. |
1802499-21-3 |
DC72509 |
Sulfo-SPP sodium
Sulfo-SPP sodium a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker. |
452072-24-1 |
DC72510 |
SC239
SC239 is a cleavable 2-aminophenyl hemiasterlin drug-linker. SC239 can be as the drug-linker for ADC. |
1977557-97-3 |
DC72511 |
Mal-VC-PAB-PNP-CDN-A
Mal-VC-PAB-PNP-CDN-A is a drug-linker conjugate for ADC. |
2640880-35-7 |
DC72512 |
Mal-Val-Ala-PABA-cGAMP
Mal-Val-Ala-PABA-cGAMP is a ADC linker that can be connected to a STING agonist. Mal-Val-Ala-PABA-cGAMP can be used for the synthesis of antibody-drug conjugates (ADCs). |
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DC72513 |
Fmoc-Ala-Ala-PAB
Fmoc-Ala-Ala-PAB is a cleavable ADC Linker (ADC Linker). Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs). |
1384263-83-5 |
DC72514 |
Mal-VC-PAB-PNP
Mal-VC-PAB-PNP is a cleavable ADC Linker (ADC Linker). Mal-VC-PAB-PNP can be used in the synthesis of antibody-drug conjugates (ADCs). |
1096584-62-1 |
DC72515 |
MC-Ala-Ala-PAB
MC-Ala-Ala-PAB is a cleavable ADC Linker (ADC Linker). Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs). |
1949793-44-5 |
DC72516 |
MP-Ala-Ala-PAB
MP-Ala-Ala-PAB is a cleavable ADC Linker (ADC Linker). Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs). |
1949793-47-8 |
DC72532 |
Fmoc-VAP-MMAE
Fmoc-VAP-MMAE is a drug-linker conjugates for ADC. Fmoc-VAP-MMAE consists of an ADC linker and a tubulin inhibitor MMAE, with a protective Fmoc group. |
1912408-91-3 |
DC72533 |
ATAC21
ATAC21, a linker-immune-stimulatory compound that can be formed by conjugating a noncleavable maleimide-PEG4 linker containing a succinimide group with an immune- stimulatory compound. ATAC21 can be combined with SBT-040 (anti-CD40 antibody) to form a conjugate. |
2101204-23-1 |
DC72753 |
Gly-Cyclopropane-Exatecan
Gly-Cyclopropane-Exatecan involves in the synthesis of anti-B7-H4 ADC, containing Exatecan, a DNA Topoisomerase I inhibitor. Gly-Cyclopropane-Exatecan participated in the formation of the ADC hu2F7-Exatecan (compound 34), which showed antitumor activity in vivo and in vitro. |
2414254-49-0 |
DC72757 |
MC-Gly-Gly-Phe-Boc
MC-Gly-Gly-Phe-Boc is involved in the synthesis of Antibody-Drug Conjugates (ADCs) to Trastuzumab. MC-Gly-Gly-Phe-Boc can participate in cancer research. |
1599440-14-8 |
DC72886 |
Dox-btn2
Dox-btn2 is a biotinylated derivative of Doxorubicin, with a biotin label at the point of conjugation to doxorubicin at 3'-NH2. Dox-btn2 can be used for cell imaging. While Doxorubicin is mainly accumulated in the nucleus, while Dox-btn2 is mainly located in the cytoplasm. |
|
DC65699 |
Mal-propyl-Ala-Ala-Asn-PAB
Featured
Mal-propyl-Ala-Ala-Asn(Trt)-PAB is a hetero bifunctional cross-linker, useful in antibody drug conjugation (ADC). |
2922956-69-0 |
DC74469 |
ZD06519
ZD06519 is a novel camptothecin payload for antibody drug conjugates (ADCs) with highp ayload potency (~1 nM). |
2873460-17-2 |
DC74470 |
SuO-Val-Cit-PAB-MMAE
Featured
A drug-linker conjugate for antibody-drug conjugate by using the anti-mitotic agent, monomethyl auristatin E (MMAE), linked via the cleavable peptide SuO-Val-Cit-PAB.. |
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DC74471 |
EN106 derivative 1
EN106 derivative 1 is a EN106 derivative used for PROTAC design, EN106 is a covalent ligand and recruiter for FEM1B E3 ligase for targeted protein degradation. |
2709040-07-1 |
DC74472 |
EN106 derivative 2
EN106 derivative 2 is a EN106 derivative used for PROTAC design, EN106 is a covalent ligand and recruiter for FEM1B E3 ligase for targeted protein degradation. |
2709040-09-3 |