Novel dual acetylcholinesterase inhibitor (AChEI) and a calcium channel blocker (CCB)

Novel inhibitor of nNOS-PSD-95 interaction, exhibiting neuroprotective activities in NMDA-induced or Oxygen and glucose deprivation (OGD)-induced neuronal damage in primary cortical neurons cultures, and ameliorating focal cerebral ischemic damage in rats

NRTI-drug pair of zidovudine (AZT)-didanosine (ddI), being highly cytotoxic and mutagenic

Novel irriversible selective PDI inhibitor, selectively labeling protein disulfide isomerase and inhibiting its enzymatic activity, showing unique cytotoxicity in cells derived from multiple myeloma

Potent inhibitor of MMP-2, -3, -9, -8, -13, and -14

Selective, surmountable antagonist for 5-HT4 receptors

Novel inhibitor of the Golgi complex (Vrg4); Antifungal

Novel immunostimulatory monosaccharidic lipid A analog, down-regulating TNF-alpha and IL-6 production and priming secretion of G-CSF and IL-1 beta

Selective 5-HT2B/2C receptor antagonist

Novel inhibitor of sterol 14a-demethylases (CYP51)

Potent antiproliferative agent, binding to the “colchicine binding site” on tubulin and inhibiting tubulin polymerization in vitro

Highly selective human tachykinin NK1 receptor antagonist

Natural plant growth inhibitor

Novel open-ring metabolite of rapamycin derivative

Antagonist of gamma-aminobutyric acid A (GABA A ) receptor and cholinergic agent

Novel Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease

Novel potent inhibitor of the enzyme soluble epoxide hydrolase (sEH)

Novel AkaLumine analog, acting asa NIR emission luciferin with the enhanced solubility in water

Novel S100B inhibitor

Novel Wnt inhibitor/Axin stabilizer

Novel potent antagonist of the Hedgehog pathway

Sentrin-specific protease 1 (SENP1) inhibitor