Novel inhibitor of pro-HGF activation

Novel Potent and Orally Bioavailable Hypoxia-Inducible Factor 2α (HIF-2α) Agonist

Fluorogenic peptide substrate for a direct fluorometric assay of urokinase, tissue-type plasminogen activator, trypsin and thrombin

Atypical analgesic agent for the amelioration of severe and chronic pain

Growth promotant, acting as a ß-AR (ß-Adrenergic) agonist

The first nonpeptidic inhibitor of ovarian cancer cells growth targeting human thymidylate synthase (hTS)

Novel antagonist for mLST8

Potent VEGFR-2 inhibitor

Novel blocker of AKT1-FAK interaction, reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620 colon cancer cells without affecting basal FAK phosphorylation

Novel Nef Protein Inhibitor; Anti-HIV

Novel TNF-α inhibitor

Novel effective immune checkpoint inhibitor (ICI) against the suppression of T-cell activation, proliferation, and tumor cell eradication.

Novel potent small molecule lligand of miR-21, binding to the major groove of miR-21 hairpin conformation

Novel TNF-α inhibitor

Potent and selective agonist of peroxisome proliferator activated receptors-α (PPAR-α)

Potent and selective agonist of peroxisome proliferator activated receptors-α (PPAR-α)

Novel SIRT1 inhibitor

Novel SIRT1 inhibitor

Novel SIRT1 inhibitor

Novel effective immune check point inhibitor (ICI) against the suppression of T-cell activation, proliferation, and tumor cell eradication.

Potent Ebolavirus (EBOV) Inhibitor

Novel dose-dependent inhibitor of TNF-α-induced NF-κB activation