ATP-sensitive potassium channel-blocker; Eukalemic diuretic

Non-steroidal pure antioestrogen

5-Lipoxygenase (5-LO) inhibitor

K-Channel opener (PCO) activating predominantly KATP channels in vitro to relax bladder detrusors

Selective nonpeptide, NK-2 receptor (NK-2R) antagonist

Potassium channel opener

Potent, selective inhibitor of Janus tyrosine kinase 3 (JAK3)

Novel antidiabetic agent for the treatment of type 2 diabetes mellitus (DM)

Inducer of functional angiogenesis through increased H 2 S availability

Potent, selective, and brain penetrating H2 receptor antagonist

Inhibitor of osteoclastogenesis and macrophage recruitment, decreasing bone turnover and stabilizing the bone matrix, exhibiting diverse anti-tumor effects in osteosarcoma

Gastroprotective agent for the treatment of peptic ulcer

Novel zinc sensor with a chloroalkane linker, reacting specifically with the engineered protein HaloTag, binding zinc ions with a threefold fluorescence enhancement

The first potent and selective Mycobacterium tuberculosis Zmp1 inhibitor

Novel potentiator of KCNQ2 potassium channels

Novel COX-2 inhibitor

Antagonist of D1 and D2 dopamine receptors.

Potent, cell-permeable and irreversible caspase-1/5 inhibitor

Natural antibiotic, having diverse biological activities including broad-spectrum antibiosis against Bacteria and lower Eukarya, plant disease suppression, and enhancement of the insecticidal activity of Bacillus thuringiensis toxin against lepidopteran l

Novel multi-target inhibitor, harboring selectivity of inhibiting EGFR T790M sparing wild-type EGFR

Novel Selective Degrader of GSPT1

Novel inhibitor of Cyclophilin J (CyPJ) PPIase, demonstrating remarkable inhibition of tumor cell growth, comparable to CsA but much stronger than 5-fluorouracil