Tofogliflozin (CSG-452) is a potent, highly selective SGLT2 inhibitor with Ki of 2.9, 14.9, and 6.4 nM against human, rat, and mouse SGLT2, respectively.

Tofogliflozin is an inhibitor of subtype 2 sodium-glucose transport protein (SGLT2).

Tolazamide is a first generation sulfonylurea that inhibits sulfonylurea receptor 1 (SUR1) linked to the inwardly rectifying potassium channel (KIR6.2; IC50 = 4.2 µM in HEK293 cells transfected with the human receptor).

Tolclofos-methyl is a broad-spectrum aromatic hydrocarbon fungicide that is used as a see treatment for protection against soil-borne and seed borne fungal pathogens that caused seed decay and seedling blights.

Tolmetin sodium dihydrate is a non-steroidal anti-inflammatory agent (NSAID) with antioxidant and neuroprotective properties.

Tolrestat(AY-27773) is a potent, orally active aldose reductase inhibitor with IC50 value of 35 nM.

Toltrazuril sulfone is an antiprotozoal agent that acts upon Coccidia parasites.

Tomeglovir (BAY 384766) is a potent, highly selective, nonnucleoside inhibitor of cytomegalovirus (CMV) replication.

Tonabersat (SB220453) is a gap-junction modulator.

Toreforant (JNJ-38518168) is a potent, selective histamine H4 receptor (H4R) antagonist with Ki of 8.4 nM, shows excellent selectivity over other receptors including the other histamine receptors.

Torezolid (TR-701; tedizolid) is a novel oxazolidinone for gram-positive infections.

Torezolid phosphate is a novel oxazolidinone for gram-positive infections, has an IC50 of 8.7 μM and 5.7 μM for monoamine oxidase (MAO)-A and MAO-B, respectively.

Tozadenant (SYN-115) is an adenosine A2A receptor antagonist.

TP003 is a potent, functional selectivity for α3 subunit-containing GABAA receptor agonist with Ki of <1 nM for α1β3γ2, α2β3γ2, α3β3γ2 and α5β3γ2, has no affinity for α4β3γ2 and α6β3γ2 (Ki>1 uM).

TP-004 is a potent, selective METAP2 (Methionine aminopeptidase-2) inhibitor..

TP0427736 is a potent inhibitor of ALK5 kinase activity with an IC50 of 2.72 nM and this effect is 300-fold higher than the inhibitory effect on ALK3 (IC50 = 836 nM for ALK3). It also inhibits Smad2/3 phosphorylation in A549 cells induced by TGF-β1 with a

TP-064 is a potent, selective, and cell-active inhibitor of PRMT4 with IC50 of <10 nM and Kd of 7.1 nM, shows high selectivity (>100-fold) for PRMT4 over other PRMTs.

TP-064N is a negative control chemical of TP-064, which is a potent, selective, and cell-active inhibitor of PRMT4 with IC50 of <10 nM..

TP-238 (TP238) is a CECR2/BPTF bromodomains chemical probe with IC50 of 30nM against CECR2 and 350nM against BPTF in an alphascreen assay, KD of 10nM for CECR2 and 120nM for BPTF in ITC assays.

TP-353,TP353

TP455 (TP-455) is a highly potent, selective A2A adenosine receptor inverse agonist with IC50 of 1.9 nM in cyclic AMP assays in hA2A CHO cells.

TP-472 is a novel BRD9/7 chemical probe that has excellent potency (BRD9 KD=33nM.