Novel potent PPARγ antagonist with much improved drug-like properties and promising pharmacokinetic profile

Selective class B inhibitor of the Ca -activated Cl- Channel, Ano1(TMEM16A)

Selective class D inhibitor of the Ca -activated Cl- Channel, Ano1(TMEM16A)

Type-A trichothecene mycotoxin

Novel inhibitor of the type III secretion system (T3SS), acting as a anti-microbial agent against Xanthomonas oryzae pv. oryzae (Xoo)

Novel Inhibitor of Adenovirus Gene Transfer

Novel Inhibitor of Adenovirus Gene Transfer

Inhibitor of HIV-1 Assembly that Targets the Phosphatidylinositol (4,5)-bisphosphate Binding Site of the HIV-1 Matrix Protein

Novel inhibitor of the catalytic functions of peroxiredoxin (Prx) and thioredoxin (Trx) systems

Natural radical scavenger on ABTS

Novel Inhibitor of Parasite Motility and Invasion

Novel Inhibitor of Parasite Motility and Invasion

Novel Irriversible Inhibitor of Parasite Motility and Invasion

Novel Potent Dual AChE/GSK-3 Inhibitor for the Treatment of Alzheimers Disease

Novel potent p53-MDM2/X antagonist, inhibiting MDM2 potently with a Ki value of 58 nmol/L, inducing accumulation of p53, p21 and MDM2, inhibiting cell cycle progression of U-2 OS cells at G1 phase in a p53-dependent manner

Novel inhibitor of the Klebsiella pneumoniae VapBC toxin-antitoxin (TA) system, acting as antimicrobial agents by disrupting the VapBC complex and activating VapC

Novel AMPA receptor potentiator with little agonistic effect, producing antidepressant-like effect without causing psychotomimetic effects

Long-lasting ergosterol biosynthesis inhibitor

Potent FAAH Inhibitor

Novel anti-HIV CCR5 antagonist

Novel selective 5-hydroxytryptamine type 2C (5-HT2C) receptor agonist

Novel inhibitor of the epigenetic modulator lysine-specific demethylase 1A (LSD1)