Cat. No. | Product name | CAS No. |
DCC5572 |
Ylt192
Novel, Orally Active Bioavailable Inhibitor of VEGFR2 Signaling with Potent Antiangiogenic Activity and Antitumor Efficacy |
1246566-47-1 |
DCC5573 |
Ylt205
Novel Inducer of Apoptosis in Human Colorectal Cells via Mitochondrial Apoptosis Pathway, Inhibiting Tumor Growth |
1316196-63-0 |
DCC5574 |
Ym-17690
Novel non-analogous leukotriene agonist |
108806-41-3 |
DCC5575 |
ym-201627
Selective growth inhibitor of endothelial cells |
326851-54-1 |
DCC5576 |
Ym-244769
Featured
YM-244769 is a potent, selective and orally active Na+/Ca2+ exchanger (NCX) inhibitor. YM-244769 preferentially inhibits NCX3 and suppresses the unidirectional outward NCX current (Ca2+ entry mode), with IC50s of 18 nM and 50 nM, respectively. YM-244769 efficiently protects against hypoxia/reoxygenation-induced SH-SY5Y neuronal cell damage. YM-244769 can also increase urine volume and urinary excretion of electrolytes in mice. |
838819-70-8 |
DCC5577 |
ym-298198 Dihydrochloride
Potent and selective mGLu1 antagonist |
299901-50-1 |
DCC5578 |
Ym-90k
Novel AMPA receptor antagonist |
143151-35-3 |
DCC5579 |
Yml220
Potent and selective microbicidal agent against wild type (wt) HIV-1, NNRTI-, NRTI-, PRI-resistant mutants |
|
DCC5580 |
Ynt-1310
Water-soluble analog of YNT-707, acting as a potent orexin 1 receptor (OX1R) antagonist |
|
DCC5581 |
Ynt-707
Novel potent orexin 1 receptor (OX1R) antagonist |
|
DCC5582 |
Yoyo-1
DNA-intercalating dye as sensitive amyloid probe |
143413-85-8 |
DCC5583 |
Ysy01a
Novel Proteasome Inhibitor, Enhancing Cisplatin Cytotoxicity in Cisplatin-Resistant Human Ovarian Cancer Cells, inducing cell cycle arrest on G2 phase in MCF-7 cells via ERα and PI3K/Akt pathways |
|
DCC5584 |
Yt-146
Selective A 2A receptor agonist |
90596-75-1 |
DCC5585 |
Yu2534342249
Novel γ-lactam pyrazolidinone, targeting penicillin-binding proteins (PBPs) and incorporating a siderophore moiety to facilitate uptake into the periplasm, being effective against multidrug-resistant gram-negative Bacilli |
|
DCC5586 |
Yw2065
Novel inhibitor of Wnt signaling by stabilizing Axin-1, a scaffolding protein that regulates proteasome degradation of β-catenin |
2131223-85-1 |
DCC5587 |
Yycg Inhibitor 16
Novel YycG inhibitor, inhibiting planktonic cells of E. faecalis, including the vancomycin- or linezolid-resistant strains |
506429-34-1 |
DCC5588 |
Yycg Inhibitor 62
Novel YycG inhibitor, significantly inhibited biofilm formation in static and dynamic conditions |
|
DCC5589 |
Yz-2-90
Novel activator of JNK, binding directly to microtubules, inducing ERK-mediated mitotic arrest and subsequent apoptosis |
1159013-10-1 |
DCC5590 |
Z118332870
Novel first-in-class inhibitor of BRD4 and EGFR kinase |
1223377-83-0 |
DCC5591 |
Z1241145220
Novel potent ligand of σ2 receptor (K i =7nM) |
|
DCC5592 |
Z1913661252
Novel riboswitch activator, binding ZTP riboswitches, and activating transcription more strongly than ZMP in vitro |
1798713-75-3 |
DCC5593 |
Z4446724338
Novel potent dual σ1/2 ligand (σ1 K i =5nM, σ2 K i =3nM), showing anti-allodynic in a model of neuropathic pain |
2445793-01-9 |