Cat. No. | Product name | CAS No. |
DC74001 |
GE1111
GE1111 is a novel potent small molecule Mas-related G protein-coupled receptor X2 (MRGPRX2) antagonist, significantly inhibits mast cells degranulation and MRGPRX2 activation with IC50 of 5 uM. |
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DC74002 |
GMFBI.1
GMFBI.1 is a small molecule that specifically block Ser83 phosphorylation site on Glia maturation factor-β (GMF-β), directly binds to hGMF-β protein with Kd of 19.9 uM. |
709608-85-5 |
DC74003 |
GNE-1858
GNE-1858 (GNE1858) is a potent, selective, ATP-competitive inhibitor of HPK1 with IC50 of 1.9 nM in the SLP76 phosphorylation assay. |
2680616-96-8 |
DC74004 |
GNF362
GNF362 (GNF-362) is a highly potent, selective inhibitor of inositol 1,4,5-trisphosphate 3-kinase B (Itpkb) with IC50 of 9 nM. |
1003019-41-7 |
DC74005 |
GNF-9228
GNF-9228 is a small molecule that stimulates human β-cell proliferation, selectively activates human β-cell relative to α- or δ-cell proliferation. |
313234-20-7 |
DC74006 |
GO-203
GO-203 (GO203) is a cell-penetrating peptide inhibitor of mucin-1-cycloplasmic C-terminal subunit (MUC1-C), blocks homodimerization of the MUC1-C subunit required for nuclear translocation and downstream signaling. |
1222186-26-6 |
DC74007 |
GQ352
GQ352 is a small molecule Gαq/11 inhibitor, directly binds to the Gαq and inhibits the dissociation of Gαβγ heterotrimers with IC50 value of 8.9 uM. |
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DC74008 |
GSK898
GSK898 is a potent, highly selective kynurenine monooxygenase (KMO) inhibitor with pIC50 of 8.8. |
1953156-92-7 |
DC74009 |
H3B-616
H3B-616 (H3B 616) is a potent, selective allosteric inhibitor of CPS1 with IC50 of 66 nM, demonstrates no appreciable inhibition of CPS2 (IC50>100 uM). |
2468199-06-4 |
DC74010 |
HB-MIX1902 Supplement (10X)
HB-MIX1902 Supplement (10X) is an optimized serum-free supplement used to promote and maintain the growth, maturity and viability of iPS-derived hepatic and biliary cells. MIX1902 is provided as a 10X liquid and is intended to be used with Hepatocyte Cult |
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DC74011 |
HJ445A
HJ445A is a highly potent, selective myoferlin (MYOF) inhibitor, binds to MYOF-C2D domain with KD value of 0.17 uM. |
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DC74012 |
HP661
HP661 is a potent, and selective oral complex I OXPHOS inhibitor with 76% inhibition at 1u M in H460 cells using electron flow assays, inhibits high-OXPHOS H460 cell viability with IC50 of 5 nM. |
2938220-60-9 |
DC74013 |
HPK1 PROTAC SS44
HPK1 PROTAC SS44 is a heterobifunctional small molecule based on ZYF0033 that simultaneously binds HPK1 and E3 ligase Cereblon (CRBN), induces degradation of HPK1. |
2636072-58-5 |
DC74014 |
HQY426
HQY426 is a specific, orally bioavailable inhibitor of pre-messenger RNA endonuclease cleavage and polyadenylation specificity factor 3 (CPSF3) with binding IC50 of 0.32 uM, exhibits potent antitumor activity. |
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DC74015 |
HQY436
HQY436 is a specific, orally bioavailable inhibitor of pre-messenger RNA endonuclease cleavage and polyadenylation specificity factor 3 (CPSF3) with binding IC50 of 0.15 uM, exhibits potent antitumor activity. |
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DC74016 |
HsClpP activator ZK53
HsClpP activator ZK53 is a potent, selective activator of mitochondrial caseinolytic protease P (HsClpP) with EC50 of 0.22 uM in FI-based protease activity assays, inactive toward bacterial ClpP proteins. |
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DC74017 |
HTL0041178
HTL0041178 is a potent GPR52 agonist with EC50 of 27.5 nM (human or rat GPR52). |
2642079-89-6 |
DC74018 |
HTS13286
HTS13286 is a selective AQP9 inhibitor with IC50 of 1.5 uM (inhibition of CHO-AQP9 cell water permeability). |
727359-12-8 |
DC74019 |
HYGIC
HYGIC is a small molecule that simultaneously induces hypocotyl elongation and thickening via the ethylene signaling pathway activated by endogenous ethylene. |
923742-91-0 |
DC74020 |
I194496
I194496 (I 194496) is a novel potent, selective inhibitor of cystathionine γ-lyase (CSE) inhibitor with IC50 of 0.79 uM. |
445238-07-3 |
DC74021 |
IBS007125
IBS007125 is a small molecule inhibitor of c-Maf, inhibits multiple myeloma proliferation by targeting cMaf transcriptional activity. |
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DC74022 |
IDE-397
IDE-397 (GSK-4362676, GSK-676) is a potent, selective small molecule methionine adenosyltransferase 2a (MAT2A) inhibitor, displays broad anti-tumor activity across a panel of MTAP-deleted patient-derived xenografts. |
2439277-80-0 |