Cat. No. | Product name | CAS No. |
DC74112 |
OV329
OV329 (OV 329) is a highly potent inactivator of gamma-aminobutyric acid aminotransferase (GABA-AT) with Ki of 9.69 uM. |
|
DC74113 |
PAANIB-1
PAANIB-1 is a brain-penetrant PAAN/MIF nuclease inhibitor that prevents neurodegeneration that prevents neurodegeneration induced by α-syn PFF, AAV-α-syn overexpression, or MPTP intoxication in vivo. |
2634726-71-7 |
DC74114 |
Panx-1 blocker 15b
Panx-1 blocker 15b is a large-pore channel pannexin 1 (Panx1) inhibitor with IC50 of 0.8 uM. |
|
DC74115 |
PAT1inh-A0030
Featured
PAT1inh-A0030 is a potent and selective SLC26A6 (putative anion transporter 1, PAT1) inhibitor with IC50 of 1.0 uM, shows no activity on relevant ion transporters/channels (SLC26A3, SLC26A4, SLC26A9, CFTR, TMEM16A). |
1030097-65-4 |
DC74116 |
PAT1inh-B01
Featured
PAT1inh-B01 is a small-molecule, selective SLC26A6 (putative anion transporter 1, PAT1) inhibitor, could fully inhibit PAT1-mediated anion exchange with IC50 of 350 nM. |
1775330-54-5 |
DC74117 |
PCC0105003
PCC0105003 is a small molecule microtubule affinity-regulating kinases (MARKs) inhibitor with IC50 of 3.0, 2.0, 2.67 and 2.67 nM for MARK1, 2, 3 and 4 repectively. |
|
DC74118 |
PCiB-1
PCiB-1 is a small molecule inhibitor capable of inhibiting phosphatidylcholine (PC) biogenesis with IC50 of 7.0 uM, inhibits phosphatidylethanolamine (PE) transport from mitochondria to the endoplasmic reticulum (ER), induces mitochondrial division. |
626219-17-8 |
DC74119 |
PCiB-2
PCiB-2 is a small molecule inhibitor capable of inhibiting phosphatidylcholine (PC) biogenesis with IC50 of 2.0 uM, inhibits the phosphatidylethanolamine (PE) methyltransferase activity of Cho2, induces mitochondrial division. |
731816-59-4 |
DC74120 |
PCiB-3
PCiB-3 is a small molecule inhibitor capable of inhibiting phosphatidylcholine (PC) biogenesis with IC50 of 0.4 uM, inhibits the phosphatidylethanolamine (PE) methyltransferase activity of Cho2. |
298190-18-8 |
DC74121 |
PDDC
PDDC is the first potent, selective, orally-available, and brain-penetrable nSMase2 (neutral sphingomyelinase 2) inhibitor with pIC50 of 6.57. |
2232878-43-0 |
DC74122 |
PEPCKi
PEPCKi is a small molecule inhibitor of hosphoenolpyruvate carboxykinase (PEPCK), blocks lactate utilization and impairs tumor growth in colorectal cancer. |
628279-07-2 |
DC74123 |
PF-07208254
PF-07208254 (PF 07208254) is a potent, allosteric branched-chain ketoacid dehydrogenase kinase (BDK) inhibitor with in vitro IC50 of 110 nM and Ki of 54 nM. |
2573122-40-2 |
DC74124 |
PF-07247685
PF-07247685 (PF-07247685) is a potent, allosteric branched-chain ketoacid dehydrogenase kinase (BDK) inhibitor with in vitro IC50 of 0.86 nM, and SPR Kd of 0.68 nM. |
|
DC74125 |
PFKL activator NA-11
PFKL activator NA-11 is a small-molecule, selective PFKL activator, inhibits the NOX2-dependent oxidative burst in neutrophils by activating the glycolytic enzyme phosphofructokinase-1 liver type (PFKL). |
2785323-65-9 |
DC74126 |
Pixatimod
Pixatimod (PG545) is a heparan sulfate (HS) mimetic and anticancer agent and a potent inhibitor of heparanase. |
|
DC74127 |
PPA904
PPA-904 is a specific phenothiazine photosensitizer in photodynamic therapy (PDT) research, especially topical application for cutaneous leishmaniasis in vivo. |
30189-85-6 |
DC74128 |
PQ912
Featured
Varoglutamstat (PQ912) is a potent glutaminyl cyclase (QC) inhibitor with Ki values of 20-65 nM for human, rat, and mouse QC activity. |
1276021-65-8 |
DC74129 |
PRG-A01
PRG-A01 is a chemical inhibitor against SOD1 misfolding and aggregation, inhibits the neuronal cell death caused by mutant-SOD1 overexpression. |
1848971-22-1 |
DC74130 |
PSB-22034
PSB-22034 is a potent, selective agonist of MAS-related Gq protein-coupled receptor X4 (MRGPRX4) with EC50 of 11.2 nM/32.0 nM in Ca2+ assay/β-arrestin assays (variant 83S), respectively. |
2768131-22-0 |
DC74131 |
PSB-22040
PSB-22040 is a potent, selective agonist of MAS-related Gq protein-coupled receptor X4 (MRGPRX4) with EC50 of 19.2 nM/30.0 nM in Ca2+ assay/β-arrestin assays (variant 83S), respectively. |
2768131-35-5 |
DC74132 |
PSB-CB-148
PSB-CB-148 is a potent, selective antagonist of GPR18. |
|
DC74133 |
PSB-CB-27
Featured
PSB-CB-27 is a potent, selective antagonist of GPR18 with IC50 of 650 nM, shows no inhibition on GPR55 and low affinity for CB1/CB2 receptors. |
2237222-16-9 |