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Cat. No. Product name CAS No.
DC60576 AZD8421 Featured

AZD8421 is a highly selective CDK2 inhibitor with IC50 of 9 nM and shows selectivity over CDK1, CDK4 and CDK6. AZD8421 shows robust monotherapy activity in a CCNE1 amplified ovarian model OVCAR3 with regressions seen with monotherapy and in combination with palbociclib.

DC65967 DBCO-PEG4-acid Featured

DBCO-PEG4-acid is a PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.

1537170-85-6
DC60577 HC-7366 Featured

HC-7366 is an orally bioavailable and efficacious GCN2 (general control nonderepressible 2) kinase activator with IC50 of 12 nM.

DC65968 Bz-(Me)Tz-NHS Featured

Bz-(Me)Tz-NHS is a click chemistry reagent containing an methyltetrazine group. Bz-(Me)Tz-NHS is 3rd generation Click-Linker for Cu-free click conjugation.

1454558-58-7
DC60578 TE-EP8-S Featured

Lipid TE-EP8-S is a one-component ionizable cationic lipid for mRNA delivery to splenic T cells.

DC60579 Lipid B3 Featured

Lipid B3 is a biodegradable ionizable lipid for liver targeted delivery. Lipid B3-LNP shows high delivery efficacy and low toxicity in delivering RNA to liver cells.

DC65969 SUN 75856 Featured

SUN 75856, also known as N-trifluoroacetyl (TFA) protected aminolink C6 phosphoramidite for the synthesis of 5'-amino-modified oligonucleotides. TFA protection is smoothly removed during ammonia deprotection, and does not require any additional steps. If necessary, the resulting oligonucleotides can be purified by ion exchange chromatography, or gel electrophoresis. This product has no formal name at the moment.

133975-85-6
DC60580 Endosidin5(ES5) Featured

Endosidine 5 (ES5), is one of the most potent small molecules interferes with recycling endosomes through Annexin A6, thereby promoting the release and expression of mRNA into the cytoplasm. The delivered mRNAs is greatly enhanced via inhibition of endocytic recycling in cells and in live mice. NAV2729 (NAV) and endosidin 5 (ES5), resulted in significant enhancement (1.5–2 folds) of LNP-mediated delivery of Fluc mRNAs. Incubation of NAV and ES5 together caused modest further increases in Fluc expression in comparison to the sole application of either compound.

DC65971 (S)-5-(3-(heptyloxy)-5-(octan-2-yloxy)benzyloxy)isophthalic acid Featured

DC65972 (R)-5-(3-(heptyloxy)-5-(octan-2-yloxy)benzyloxy)isophthalic acid Featured

DC65973 5-(3-((R)-octan-2-yloxy)-5-((S)-octan-2-yloxy)benzyloxy)isophthalic acid Featured

DC65974 5-(3,5-bis((S)-octan-2-yloxy)benzyloxy)isophthalic acid Featured

DC65975 5-(3,5-bis((R)-octan-2-yloxy)benzyloxy)isophthalic acid Featured

DC65976 5-(3-(heptan-2-yloxy)-5-(hexyloxy)benzyloxy)isophthalic acid Featured

DC65977 5-(3,5-bis(heptan-2-yloxy)benzyloxy)isophthalic acid Featured

DC65978 1-[1-Phenyl-3,4-dihydro-1h-pyrido[3,4-b]indol-2(9h)-yl]pentan-1-one Featured

334939-35-4
DC65979 HT-2157 Featured

303149-14-8
DC65980 NSC 102533 Featured

NSC 102533 (Compound N3) is a potent inhibitor of mitochondrial electron transport. Antimalarial agent 14 can serve as an anti-malarial agent.

1150-59-0
DC65981 (S)-2-acetamido-3-(4-methylbenzoylthio)propanoic acid Featured

1695562-36-7
DC65982 10-METHYL-9-(PHENOXYCARBONYL)ACRIDINIUM FLUOROSULFONATE Featured

10-Methyl-9-(phenoxycarbonyl)acridinium fluorosulfonate, a phenyl ester of acridinium esters, is a fluorescent dye that produces chemiluminescent under neutral conditions. 10-Methyl-9-(phenoxycarbonyl)acridinium fluorosulfonate can be used for the measurement of hydrogen peroxide.

149300-54-9
DC65983 10-Methyl-9-(phenoxycarbonyl) Acridinium (trifluoromethylsulfonate) Featured

161006-14-0
DC65984 Indole-3-acetyl-L-tryptophan Featured

57105-53-0
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