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Cat. No. Product name CAS No.
DC66306 WAY-328182 Featured

restore E-cadherin expression in the SW620 colon adenocarcinoma cell line

912787-60-1
DC66307 WAY-328168 Featured

antagonist of the NK3 receptor; altering the lifespan of a eukaryotic organism;

909856-46-8
DC66308 WAY-299775 Featured

potential leads for chaperone therapy for Gaucher disease

333441-43-3
DC66309 NFATc1-IN-1 Featured

NFATc1-IN-1 (compound A04) is a potent inhibitor of RANKL-induced osteoclast formation, with an IC50 of 1.57 μM. NFATc1-IN-1 shows anti-osteoclastogenic effects through reducing the RANKL-induced nuclear translocation of NFATc1. NFATc1-IN-1 can be used for osteoclastic diseases research.

1912422-56-0
DC66310 WAY-388798 Featured

63417-81-2
DC66311 BRD4 Inhibitor-24 Featured

BRD4 Inhibitor-24 (compound 3U) is a potent BRD4 inhibitor, BRD4 Inhibitor-24 shows antitumor activity against MCF7 and K652 cells, with IC50 values of 33.7 and 45.9 μM, respectively.

309951-18-6
DC66312 DB2313 HCl Featured

DB2313 is a first-in-class potent small-molecule inhibitor of PU.1. DB2313 disrupts the interaction of PU.1 with target gene promoters and leads to down-regulation of canonical PU.1 transcriptional targets.

2170606-75-2
DC66313 WAY-301158 Featured

antitubercular activity; fungicidal activity;

71134-64-0
DC66314 WAY-310301 Featured

anti-inflammatory, COX inhibitory activities and ulcerogenic liability

332921-97-8
DC66315 WAY-326101 Featured

glucocerebrosidase activator;

869714-27-2
DC66316 BMS-P5 HCl Featured

BMS-P5 is a Novel Peptidylarginine Deiminase 4 (PAD4) Inhibitor with pIC50 values in the range of 5-​7.5. BMS-P5 Blocks Formation of Neutrophil Extracellular Traps and Delays Progression of Multiple Myeloma. Administration of BMS-P5 to multiple myeloma-bearing mice delays appearance of symptoms and disease progression Targeting PAD4 may be beneficial for treatment of multiple myeloma.

1549811-36-0
DC66318 WAY-301522 Featured

68380-53-0
DC66319 WYE-176249 Featured

VEGF inhibitor

304881-10-5
DC66320 WAY-301122 Featured

cytotoxity (targeted to DNA topoisomerase II); anti-cancer activity; fungicides;

76111-24-5
DC66321 WAY-328141 Featured

useful for the treatment of cystic fibrosis; modulating CFTR activity; altering the lifespan of a eukaryotic organism;

688050-36-4
DC66322 WAY-327512 Featured

activate TLR8-dependent NF-kB signaling

252725-86-3
DC66323 WAY-270252 Featured

IGF-1R/SRC inhibitor

61-38-1
DC66324 WAY-358024 Featured

GSK-3b inhibitors; GSK-3b inhibitors;

70169-39-0
DC66325 CB2R PAM Featured

CB2R PAM is an orally active cannabinoid type-2 receptors (CB2Rs) positive allosteric modulator. CB2R PAM displays antinociceptive activity in vivo in an experimental mouse model of neuropathic pain.

2244579-87-9
DC66326 Ropidoxuridine Featured

Ropidoxuridine (IPdR) is a novel orally available, halogenated thymidine analog and is a potential radiosensitizer for use in human tumors.

93265-81-7
DC66327 Antibacterial agent 125 Featured

Antibacterial agent 125 is an antibacterial agent. Antibacterial agent 125 has a potent antimicrobial activity against clinically relevant Gram-positive pathogens with MIC50 values range from 0.25 - 8 μM. Antibacterial agent 125 can be used for the research of antimicrobial resistance.

1274611-43-6
DC66328 OTS514 hydrochloride Featured

OTS514 hydrochloride is a highly potent TOPK inhibitor, which inhibits TOPK kinase activity with a median inhibitory concentration (IC50) value of 2.6 nM. OTS514 hydrochloride strongly suppresses the growth of TOPK-positive cancer cells. OTS514 hydrochloride induces cell cycle arrest and apoptosis.

2319647-76-0
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