Cat. No. | Product name | CAS No. |
DC5027 |
ABC294640(Opaganib)
Featured
ABC294640 is an orally available, aryladamantane compound and selective inhibitor of sphingosine kinase-2 (SK2) with potential antineoplastic activity. |
915385-81-8 |
DC24211 |
Abiraterone (D4A)
Featured
Abiraterone (D4A) is an active metabolite of the CYP17A1 inhibitor abiraterone. |
154229-21-7 |
DC20619 |
ABL127
Featured
ABL127 (ML174) is a potent, selective, covalent inhibitor of protein methylesterase 1 (PME-1) with IC50 of 10 nM. |
1073529-41-5 |
DC8667 |
AB-MECA
Featured
AB-MECA is a high affinity A3 adenosine receptor agonist, has high affinity for recombinant A1 and A3 receptors. |
152918-26-8 |
DC2002 |
Venetoclax(ABT-199)
Featured
ABT-199 is a Bcl-2-selective inhibitor with Ki < 0.010 nM. |
1257044-40-8 |
DC4127 |
ABT-263 (Navitoclax)
Featured
ABT-263 (Navitoclax) is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of ≤ 0.5 nM, ≤1 nM and ≤ 1 nM, respectively. |
923564-51-6 |
DC7352 |
ABT-333
Featured
ABT-333 is an NS5B non-nucleoside polymerase inhibitor. |
1132935-63-7 |
DC10049 |
Tebanicline(ABT-594)
Featured
ABT-594 represents a novel class of broad-spectrum analgesics whose primary mechanism of action is activation of the neuronal nicotinic acetylcholine receptors. |
198283-73-7 |
DC9706 |
ABT-639
Featured
ABT-639 is a novel, peripherally acting, selective T-type Ca2+ channel blocker. ABT-639 blocks recombinant human T-type (Cav3.2) Ca2+ channels in a voltage-dependent fashion (IC50 = 2 μM) and attenuates LVA currents in rat DRG neurons (IC50 = 8 μM). |
1235560-28-7 |
DC10723 |
ABT-702
Featured
ABT-702 is a potent non-nucleoside adenosine kinase inhibitor (IC50 = 1.7 nM), selective over other sites of adenosine interaction (A1, A2A and A3 receptors, adenosine transporter and adenosine deaminase). |
1188890-28-9 |
DC9262 |
ABT-719
Featured
ABT-719 is a potent bacterial DNA gyrase inhibitor. |
162829-90-5 |
DC9261 |
ABT-719 HCl
Featured
ABT-719 is a potent bacterial DNA gyrase inhibitor. |
162763-53-3 |
DC1022 |
ABT-737
Featured
ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w with EC50 of 78.7 nM, 30.3 nM and 197.8 nM, respectively. |
852808-04-9 |
DC7353 |
ABT-751(E 7010)
Featured
ABT-751(E 7010) is a novel bioavailable tubulin-binding and antimitotic sulfonamide agent with IC50 of about 1.5 and 3.4 μM in neuroblastoma and non-neuroblastoma cell lines, respectively. |
141430-65-1 |
DC4231 |
Linifanib (ABT-869)
Featured
ABT-869 is an ATP-competitive, multi-targeted RTK inhibitor that is completely effective against all members of the vascular endothelial growth factor (VEGF) and platelet derived growth factor (PDGF) receptor families. |
796967-16-3 |
DC11155 |
ABX-1431
Featured
ABX-1431 (ABX1431) is a highly potent, selective, orally available, CNS-penetrant monoacylglycerol lipase (MGLL) with IC50 of 14 nM (hMGLL). |
1446817-84-0 |
DC11183 |
ABX-1431 hydrochloride
Featured
ABX-1431 (ABX1431) is a highly potent, selective, orally available, CNS-penetrant monoacylglycerol lipase (MGLL) with IC50 of 14 nM (hMGLL). |
2043074-64-0 |
DC23182 |
ABX464
Featured
ABX464 (ABX-464, ABX 464) is a novel class of anti-HIV small molecule targeting Rev-mediated viral RNA biogenesis, shows dose dependent inhibition of HIV-1 replication in stimulated PBMCs with IC50 of 0.1-0.5 uM. |
1258453-75-6 |
DC7698 |
AC 55541
Featured
AC 55541 is a potent and selective protease-activated receptor 2 (PAR2) agonist (pEC50 = 6.7) that displays no activity at other PAR subtypes or at over 30 other receptors involved in nociception and inflammation. |
916170-19-9 |
DC11508 |
AC1903
Featured
AC1903 is a specific and selective inhibitor of TRPC5 and has podocyte-protective properties. AC1903 does no effects on TRPC4 or TRPC6 currents and shows no off-target effects in kinase profiling assays. AC1903 suppresses severe proteinuria and prevents podocyte loss in focal segmental glomerulosclerosis (FSGS) rat model. |
831234-13-0 |
DC12577 |
AC-263093
Featured
AC-263093 (AC263093) is a potent, functionally selective neuropeptide FF receptor type 2 (NPFFR2) agonist with pKi of 6.9. |
849459-86-5 |
DC10117 |
AC264613
Featured
AC264613 is a potent and selective protease-activated receptor 2 (PAR2) agonist (pEC50 = 7.5). Displays no activity at other PAR subtypes and exhibits no significant activity at over 30 other receptors implicated in nociception and inflammation. |
1051487-82-1 |