Cat. No. | Product name | CAS No. |
DC60227 |
Cadralazine
Featured
Cadralazine is a peripheral arteriolar vasodilator and an antihypertensive drug. |
64241-34-5 |
DC60228 | KCNQ1 activator-1 Featured | 1008671-38-2 |
DC60229 |
VU0360172
Featured
VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM). VU0360172 is selective for mGlu5 and it displays no significant activity at mGlu1, mGlu2 or mGlu4 receptors. |
1310012-12-4 |
DC60230 |
RUVBL1/2 ATPase-IN-1
Featured
RUVBL1/2 ATPase-IN-1 (compound 18) is a potent and selective inhibitor of RUVBL1/2 ATPase with IC50 values of 6.0 and 7.7 μM, respectively. RUVBL1 and RUVBL2 are highly conserved AAA ATPases (ATPases Associated with various cellular Activities) and highly relevant to the progression of cancer. RUVBL1/2 ATPase-IN-1 has the potential for the research of cancer diseases. |
423128-55-6 |
DC60232 | CL-418030 Featured | 1093748-54-9 |
DC60233 | WYE-176092 Featured | 121746-06-3 |
DC60234 |
PF-06821497
Featured
PF-06821497 (compound 23a) is a potent, selective and orally active Enhancer of Zeste Homolog 2 (EZH2) inhibitor, with a Ki value <0.1 nM against mutant Y641N EZH2. Exhibits robust tumor growth inhibition. |
1844849-10-0 |
DC60235 | Hydrazinium hydroxide Featured | 1805818-57-8 |
DC60236 | Imiquimod hydrochloride Featured | 99011-78-6 |
DC60237 | 7-Chlorokynurenic acid sodium salt Featured | 1263094-00-3 |
DC60238 |
AM103
Featured
AM 103 is a potent and selective FLAP inhibitor, with an IC50 value of 4.2 nM. |
1147872-22-7 |
DC60239 | Uridine 5′-diphosphoglucose Featured | 28053-08-9 |
DC60240 | (S)-PF-06873600 Featured | 2185859-59-8 |
DC60241 | FluvoxaMine Featured | 54739-18-3 |
DC71588 |
SRI-37330 hydrochloride
Featured
SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. SRI-37330 hydrochloride inhibits glucagon secretion and function, reduces hepatic glucose production and reverses hepatic steatosis. SRI-37330 hydrochloride can be used for type 2 diabetes research. |
2322245-49-6 |
DC71590 |
(Rac)-CFT7455
Featured
(Rac)-CFT7455 is a zinc finger transcription factors Ikaros (IKZF1) and Aiolos (IKZF3) degrader, acting via the ubiquitin proteasome pathway, with a GI50 of 0.05 nM for NCIH929.1 cells. (Rac)-CFT7455 is the racemic isomer of CFT7455 which is a IKZF1/IKZF3 degrader with anticancer activity. |
2504233-68-3 |
DC71608 |
Euquinine
Featured
Euquinine is generally used as a febrifuge, antimalarial, and tonic. |
83-75-0 |
DC71612 |
NTQ1062
Featured
NTQ1062 (compound 22b) is a potent and orally active Akt inhibitor with IC50s of 0.4 nM, 6.3 nM and 0.1 nM for Akt1, Akt2 and Akt3, respectively. NTQ1062 induces cell apoptosis and arrests the cell cycle at G0/G1 phase. |
2459489-66-6 |
DC71625 |
Tivozanib hydrochloride hydrate
Featured
Tivozanib hydrochloride hydrate is a potent and selective and orally active VEGFR tyrosine kinase inhibitor with IC50是of 0.21, 0.16, 0.24 nM for VEGFR-1, VEGFR-2, VEGFR-3, respectively. Tivozanib hydrochloride hydrate inhibits angiogenesis and vascular permeability in tumor tissues and shows antitumor activity. Tivozanib hydrochloride hydrate has the potential for the research of metastatic renal cell carcinoma (RCC) . |
682745-41-1 |
DC71627 |
Ansornitinib
Featured
Ansornitinib is an orally active dual kinase inhibitor that inhibits platelet-derived growth factor receptor (PDGFR) and vascular endothelial growth factor receptor (VEGFR2). Ansornitinib can be used as an antifibrotic agent in lung, liver, kidney, and gastrointestinal fibrotic diseases. |
1448874-96-1 |
DC71628 |
WAY-340935
Featured
WAY-340935 (VEGFR2-IN-2) can inhibit the function of VEGFR2 and the anti-proliferative activity against the H460 cell line is produced partly by interaction of VEGFR protein. |
737818-56-3 |
DC71650 |
BVDV IN-1
Featured
BVDV IN-1 is a non-nucleoside inhibitor of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. |
345651-04-9 |