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(Rac)-CFT7455

Cat. No.: DC71590 Featured

Chemical Structure

2504233-68-3

For research use only. We do not sell to patients.

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Field of application

(Rac)-CFT7455 is a potent, racemic small-molecule degrader of the zinc finger transcription factors IKZF1 (Ikaros) and IKZF3 (Aiolos), operating through ubiquitin-proteasome-mediated degradation. It demonstrates exceptional cellular potency, with a GI50 of 0.05 nM in NCI-H929.1 cells. As the racemic form of CFT7455, it retains the same anticancer activity by selectively targeting IKZF1/3 for proteasomal destruction.

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:	2504233-68-3
Chemical Name:	(Rac)-Cemsidomide
Synonyms:	2,6-Piperidinedione, 3-[6-[[4-(4-morpholinylmethyl)phenyl]methyl]-2-oxobenz[cd]indol-1(2H)-yl]-;(Rac)-Cemsidomide
SMILES:	N1C(=O)CCC(N2C3=C4C(C=CC=C4C2=O)=C(CC2=CC=C(CN4CCOCC4)C=C2)C=C3)C1=O
Formula:	C₂₈H₂₇N₃O₄
M.Wt:	469.53
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC68076	BG-BRD4-P07
DC68075	BRU-SHP2-P06
DC68074	LLY-ESR1-P05
DC68073	AST-AR-P04
DC68072	NOV-EP001
DC68071	JHU-MDM2-P03
DC68070	CAS-FAK-P02
DC68069	MDA-S24-P01
DC68068	TB-008
DC68067	ARV-863

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.