Novel fluorescent activity-based probe (ABP), being intrinsically dark and only emitting fluorescence after reaction with the target protease, are ideally suited for imaging techniques such as small animal noninvasive fluorescence imaging and live cell fl

Potent long-acting H2-receptor antagonist

Novel CD4 mimic, inhibiting HIV-1 entry into target cells with both significantly higher potency and neutralization breadth than previous congeners, while maintaining high selectivity for the target virus

Solvatochromic Nile Red Probe with FRET Quencher Reveal Lipid Order Heterogeneity in Living and Apoptotic Cells

Selective delta 1 opioid receptor antagonist

Inhibitor of topoisomerase I/II, inducing DNA cross-linking and significantly suppressing the growth of various NSCLC cell lines with or without mutations in epidermal growth factor receptor (EGFR)

Novel covalent substrate-competitive inactivator of AKT kinase

Novel Fluorescent, Highly Affine Histamine H3 Receptor Ligand

Fluorogenic dye for Live-Cell Fluorescence Microscopy

Novel fluorogenic dye for Live-Cell Fluorescence Microscopy

Natural inhibitor of protein tyrosine phosphatase 1B (PTP1B)

Potent Botulinum Neurotoxin A Light-Chain Inhibitor

Novel potent inhibitor of Botulinum neurotoxin/A light chain (BoNT/A LC)

Novel BOP-conjufated fluorescent dual α9β1/α4β1 integrin inhibitor

Novel. highly potent, selective, cell-permeable furin inhibitor, rescuing key features of cystic fibrosis airway disease

Proteolysis targeting chimeras (PROTAC), acting as a degrader of oncogenic BCR-ABL

Novel IKK-2 inhibitor, targeting the Ser177 and/or Ser181 residues in the kinase's activation loop domain.

Novel and highly potent histamine H3 receptor ligand

Potent and selective STAT5 inhibitor

Novel, Potential Dengue Virus NS2B/NS3 Protease Inhibitor

Histamine H3 receptor agonist prodrug

Novel modulator of TTD-PHD histone reader module, binding to the TTD groove, competing with linker binding and promoting open TTD-PHD conformations