Novel cell-permeable, potent, reversible, and substrate competitive LSD1 inhibitor, promoting the adipogenic differentiation of hESCs

Novel inhibitor of viral transcriptional elongation, blocking both HIV-1 replication and reactivation

NF-kappa B (NF-kB) inhibitor and p53 activator

Novel selective inhibitor of KDM4s, inhibiting all members of the KDM4(A-E) subfamily

Novel KDM4 inhibitor, inhibiting equally all members of the KDM4 family and exhibiting modest selectivity over other JmjC-KDMs including KDM2A and PHF8

Novel Dual p38α MAPK/PDE-4 Inhibitor with Activity against TNFα -related Diseases

The first Gatekeeper RXR antagonist that does not show allosteric inhibition in permissive RXR heterodimers, binding domain (LBD) at the entrance of the ligand binding pocket (LBP), blocking access to the LBP and thus serving as a gatekeeper

FTY720 derivative

Novel inhibitor of the E2 ubiquitin-conjugating enzyme Cdc34A

Novel Cereblon modulator, promoting ZBTB16 degradation by primarily engaging distinct structural degrons on CRBN-ZnF1 zinc finger domains

PqsE inhibitor, binding to the active center inhibiting PqsE's thioesterase activity in cell-based and in vitro assays

PqsE inhibitor, binding to the active center inhibiting PqsE's thioesterase activity in cell-based and in vitro assays

Novel potent orally bioavailable Syk kinase inhibitor

Novel Cereblon modulator, promoting ZBTB16 degradation by primarily engaging distinct structural degrons on CRBN-ZnF3 zinc finger domains

Novel Indigoid Anti-tuberculosis Agent; Antimicrobial

Novel coupleable ceritinib analog with a linker, also binding multiple other kinases, including FAK1, RSK1/2, ERK1/2, CAMKK2 and FER

Novel Inhibitor of TonB Function

Novel Inhibitor of TonB Function

Potent photoprobe as Rho/MKL1/SRF transcription inhibitor

Novel inhibitor of G Protein-Coupled Receptor Kinase

Novel covalent selective GRK inhibitor, interacting with a nonconserved cysteine (Cys474)

Novel sialyltransferase inhibitor (IC 50 : 2 µM)