Novel CK2 inhibitor, targeting an allosteric pocket, exhibiting an IC50 of 3.4 μM against purified CK2α in combination with a favorable selectivity profile

Novel potent and selective inhibitor of CK2. modulating the aforementioned signaling cascades and counteracting 17-AAG-mediated up-regulation of HSP70 in brain cancer cells

Novel cell-permeable and selective inhibitor of human protein kinase CK2, inducing apoptosis in the prostate cancer cell line LNCaP

Novel inhibitor of CK2α, binding in the ATP pocket

Inhibitor of vascular adhesion molecule-1 (VCAM-1), HMGB1 phosphorylation, iNOS expression, NFkB activation; Antiinflammatory

Natural Dual Inhibitor for Wild Type and D816V Mutant of c-KIT Kinase

Negative control for CK156

Inhibitor of H5N1 avian influenza A virus infection

Inhibitor of respiratory syncytial virus (RSV)

Novel potent inhibutor of HIV-1 integrase

Novel protein tyrosine phosphatase-1B (PTP1B) inhibitor, neutralizing the toxicity of α-hemolysin, inhibiting β-secretase 1 (BACE1)-mediated insulin receptor cleavage

The most potent clathrin terminal domain-amphiphysin inhibitor reported to date

Natural modulator of voltage-gated sodium (NaV) channels

Novel two-photon polarity-sensitive lipid membrane probe

Antibiotic, acting as a mechanism-based β-lactamase inhibitor

Novel hypoxia-inducible factor (HIF)-1 inhibitor

Prostaglandin I2 analogue, dose-dependently inhibiting human and rabbit platelet aggregation and human platelet adhesion in vitro

Potent CLK1 and CLK2 inhibitor, also inhibiting SRPK1 and SRPK2

Potent and selective CLK1 and CLK2 inhibitor

Novel inhibitor of the human enzyme dimethylarginine dimethylaminohydrolase-1 (DDAH-1)

Corticosteroid Hormone Receptor Agonist

Hypolipaemic agent, reducing hypertriglyceridemia and hypercholesterolemia