Novel Inhibitor for RNA-Dependent RNA Polymerase of Norovirus

Novel Potent Inhibitor of the HIV-1 Nucleocapsid Protein

Novel Zika virus (ZIKV) NS2B-NS3pro protease inhibitor

Novel blocker of binding of CXCL12 to CXCR4

Novel partial blocker of GluK1, with GluK2 being unaffected

Novel potent and selective blocker of the calcineurin-NFAT interaction (KD=16nM), preventing acute lung injury, being a promising novel treatment for ARDS and other inflammatory diseases

N-methyl-D-aspartate (NMDA) receptor ligand, selectivity targeting the intrachannel PCP/ketamine/MK-801 site of NMDA receptor

Novel and selective noncompetitive antagonist of the NMDA

Novel potent RIPK1/necroptosis ligand, penetrate the blood-brain barrier

Novel inhibitor of mitogen-activated protein kinase (MAPK)

Bioluminescent probe

Natural lariat depsipeptide, inhibiting VEGFA/VEGFR2 expression and suppressing tumor growth in glioblastoma xenografts, targeting Sec61 to prevent biogenesis of secretory and membrane proteins

Novel potent and selective inhibitor of the interaction between Hsp47 and collagen

Novel potent and selective inhibitor of the interaction between Hsp47 and collagen

Novel potent and selective inhibitor of the interaction between Hsp47 and collagen

Natural differentiation inducer of human promyelocytic leukemia cells

Inhibitor of tubulin polymerization, preventing cancer cells from producing microtubules

Inhibitor of tubulin polymerization; vascular disrupting agent (VDA)

Inducer of G2/M-phase cell cycle arrest and cell death in cancer cell lines

Dual inhibitor of phospholipid transfer protein and microsomal triglyceride transfer protein

Novel inducer of Klotho (KL) expression

Natural triketide pyrone, functioning as a sulfate shuttle and its sulfated derivative being accepted as donor molecules by the PAPS-independent arylsulfate sulfotransferase (ASST) Cpz4 to yield sulfated caprazamycin intermediate