Novel low-impact ampakine that can safely activate AMPA receptors without causing excito-neurotoxicity, rapidly crossing the blood-brain barrier (T max = 2 min), protecting against respiratory depression

Novel inhibitor of CXCL8-mediated chemotaxis through selective regulation of CXCR2-mediated signaling

Nonsteroidal dermatologic and anti-inflammatory agent, blocking the MEK1/2-Erk1/2 pathway, inhibiting chronic contact hypersensitivity responses (CHRs) and the rebound phenomenon following withdrawal of corticosteroid therapy without immunosuppression

Novel potent CXCR2 antagonist

Novel CXCR2 selective antagonist with a low CXCR1 antagonism preference

Selective D1 agonist with anti-Parkinsonian activity

Novel ABA receptor agonist, preferentially activating Pyrabactin Resistance 1 (PYR1) with low nanomolar potency

Androgen receptor (AR) antagonist, inhibiting AR function in castrate-resistant prostate cancer (CRPC)

Blue fluorescent amino acid, exhibiting blue fluorescence (λ max ~ 405 nm) with a high quantum yield and long lifetime

Novel Effective Aminoluciferin Derivative for Deep Bioluminescence Imaging

Natural antibacterial peptide, activating the AAA+ protease ClpC/ClpP, causing cell death by uncontrolled protein degradation

Novel PD-1/PD-L1 inhibitor, binding two PD-L1 and efficiently block the PD-1/PD-L1 interaction

Natural irreversible inhibitor of acetylcholinesterase (AChE)

Novel bicyclic peptidyl pan-Ras inhibitor, binding selectively to the GTP-bound forms of wild-type and mutant Ras isoforms (K D = 21 nM for KRasG12V-GppNHp) and being highly cell-permeable and metabolically stable (serum t1/2 > 24 h)

Novel Cyclic Peptide Inhibitor of the p6/UEV Protein-Protein Interaction, disrupting the p6/UEV interaction with an IC50 of 6.17 ± 0.24 μM by binding to UEV with a Kd of 11.9 ± 2.8 μM.

Immunosuppressant

Immunosuppressant

Macrocyclic immunosuppressive peptide, exhibiting a higher plasma concentration than Cyclophilin A

immunosuppressive agent

Cyclic alkylaminoluciferin substrate for firefly luciferase

Cyclic alkylaminoluciferin substrate for firefly luciferase, emitting 4.7-fold more light than aminoluciferin, and 2.6-fold more light than D-luciferin

Non-peptidic, potent, and orally active stromelysin inhibitor;