Cyclic alkylaminoluciferin substrate for firefly luciferase

Novel S1PR4 antagonist

Novel non-peptidic NPBWR1 (GPR7) antagonist

Novel short-acting KOR antagonist

Potent and selective human CYP11B1 inhibitor

Novel potent and selective CYP1A1 inhibitor, antagonizing B[a]P mediated activation of aromatic hydrocarbon receptor (AhR) in yeast cells, and protecting human cells from CYP1A1-mediated B[a]P toxicity in human cells

Novel covalent allosteric CYP3A4-effector

Novel fungal lanosterol 14α-demethylase (CYP51)/histone deacetylase dual inhibitor, blocking ergosterol biosynthesis and HDAC catalytic activity in fungus, suppressing the function of efflux pump, yeast-to-hypha morphological transition, and biofilm forma

Novel CypD inhibitor, binding strongly to CypD and attenuating mitochondrial and cellular perturbation insulted by Aß and calcium stress

Novel non-peptidic inhibitor of cyclophilin D as neuroprotective agents in Aβ-induced mitochondrial dysfunction

Novel potent tri-vector cyclophilin inhibitor

Inhibitor of Pentaglycine Interpeptide Bridge Synthesis

NRAS inhibitor, targeting the post-translational S-palmitoyl modification of NRAS, causing a dose-dependent decrease in NRAS palmitoylation and inhibiting downstream signaling in melanoma cells with an activating mutation in NRAS

Inhibitor of cholinesterase activity, β-amyloid aggregation and Ca overload; Novel multi-target-directed ligand (MTDL); Activator of kinase 1 and 2 (ERK1/2) and Akt/protein kinase B (PKB) pathways

Inhibitor of cysteine protease

Unique first-in-class antibiotic, being more effective at killing pathogenic methicillin resistant Staphylococcus aureus (MRSA) bacteria than two clinical gold-standard antibiotics-vancomycin and gentamicin

Unique first-in-class antibiofilm antibiotic for biofilm-related wound infections caused by Acinetobacter baumannii

Highly potent and selective H4R antagonist

Novel potent, selective and metabolically stable LRRK2 inhibitor

Novel antiviral agent, blocking microtubule polymerization, disrupting the Golgi complex and inhibiting viral trafficking to the plasma membrane during virus egress

Promoter of spinal muscular atrophy (SMA)

Novel ERK2 inhibitor