Novel potent inhibitor of the recombinant FLT3 kinase and its mutant forms, blocking the proliferation of AML cell lines, harboring oncogenic FLT3-ITD mutations with remarkable IC50 values, which were comparable to the approved FLT3 inhibitor quizartinib,

Novel inhibitor of lipoteichoic acid (LTA) biosynthesis, potently inhibiting S. aureus and E. faecalis growth and biofilm formation

Novel Peripherally-Restricted Kappa Opioid Receptor (KOR) Agonist with Antinociceptive and Antipruritic Effects

Novel inhibitor of heat shock 27 kDa protein (HSP27), significantly inducing AR degradation in GBM cells via the proteasomal pathway, selectively inhibiting AR-overexpressed GBM cell growth with IC 50 values around 5 nM

Novel Hsp90-Aha1 chaperone complex formation inhibitor, enhancing F508del-CFTR channel activity

Novel potent inhibitor of heat shock protein 90 (Hsp90), effectively reducing the expression levels of Hsp90 client proteins including Her2, EGFR, Met, Akt, and c-Raf

Novel heat shock protein 90 (Hsp90) inhibitor

Novel heat shock protein 90 (Hsp90), more potent enantiomer

Novel macrocyclic calcitonin gene-related peptide (CGRP) receptor antagonist

Novel macrocyclic calcitonin gene-related peptide (CGRP) receptor antagonist

Novel allosteric antagonist of the glucagon-like peptide-1 receptor (GLP-1R)

Novel, potent, selective, and orally efficacious dual antagonist of the orexin receptors

Novel activator of PC2

Novel analgesic agent, activating TRPA1 and subsequently desensitizing the channel, exhibiting higher inhibitory activity than resveratrol

Adhesive peptide (sequence 351-359 mapped on the Human Vitronectin Protein), covalent and selective functionalizing on glass and titanium surfaces, increasng osteoblast attachment and adhesion strength and to promoting osseointegration

Novel human antigen R (HuR) ligand, acting as a HuR-RNA interferer

Novel CK2-Specific Pt(II) Compound, Reversing Cisplatin-Induced Resistance by Inhibiting Cancer Cell Stemness and Suppressing DNA Damage Repair in Non-small Cell Lung Cancer Treatments

Inhibitor of apurinic endonuclease-1 (APE1) by direct protein binding

Activable Probe for Noninvasive Hydroxyl Radical Imaging, emitted in 1000-1400 nm after responding to ·OH

Novel multitarget Fasudil derivative, inducing the NRF2 signature, promoting the expression of the antioxidant response enzymes HO-1 and NQO1, via a KEAP1-dependent mechanism

Novel potent and selective inhibitor of Schistosoma mansoni dihydroorotate dehydrogenase (SmDHODH)

Novel selective r(CGG)exp probe, improving pre-mRNA splicing defects, inhibiting formation of nuclear inclusions and RANT in a FXTAS cellular model